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MD (Pharmacology), MBBS
Last updated:
27 Dec 2019 | 01:08 PM (IST)
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Holoxan 1gm Injection

Prescription Required

Overview

Introduction

Holoxan 1gm Injection is used in the treatment of different kinds of cancers. It is given alone or in combination with other chemotherapy medicines, radiotherapy and surgery to treat cancer of blood, breast, lung, ovaries, pancreas, testes, and lymph nodes.

Holoxan 1gm Injection is usually given as a slow infusion (drip) into a vein (intravenously) over several hours. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cells count.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped.

Side effects of Holoxan Injection

Common
  • Nausea
  • Vomiting
  • Anemia (low number of red blood cells)
  • Hair loss
  • Decreased white blood cell count
  • Infection
  • Blood in urine
  • Cns toxicity

How to use Holoxan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Holoxan Injection works

Holoxan 1gm Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Holoxan 1gm Injection.
Pregnancy
CONSULT YOUR DOCTOR
Holoxan 1gm Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Holoxan 1gm Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Holoxan 1gm Injection may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Holoxan 1gm Injection should be used with caution in patients with kidney disease. Dose adjustment of Holoxan 1gm Injection may be needed. Please consult your doctor.
Liver
CAUTION
Holoxan 1gm Injection should be used with caution in patients with liver disease. Dose adjustment of Holoxan 1gm Injection may be needed. Please consult your doctor.

What if you forget to take Holoxan Injection?

If you miss a dose of Holoxan 1gm Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Holoxan 1gm Injection
₹393.89/Injection
Celofos 1gm Injection
Celon Laboratories Ltd
₹885/ml of Injection
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Isoxan 1gm Injection
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₹425/Injection
8% costlier
Ifopar 1gm Injection
Parenteral Drugs India Ltd
₹470/Injection
19% costlier
Fosfa 1gm Injection
Getwell Oncology Pvt Ltd
₹485/Injection
23% costlier
Ifoneon 1gm Injection
Neon Laboratories Ltd
₹238.09/Injection
save 40%

Quick Tips

  • Holoxan 1gm Injection is used in combination with other chemotherapy medicines, radiotherapy and surgery to treat cancer of blood, breast, lung, ovaries, pancreas, testes, and lymph nodes.
  • It is usually given as a slow infusion (drip) into a vein (intravenously) over several hours.
  • Drink plenty of fluids while taking this  medication to minimise damage to your bladder and kidneys.
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Use effective measures to avoid pregnancy during treatment with this medicine and for at least 6 months after your last dose as it can be harmful to an unborn baby. 
  • Your doctor may have your blood tested regularly to monitor your kidney, liver function and levels of blood cells in your blood.

Patient Concerns

arrow
I want to know the symptoms of cancer as I am a smoker
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
arrow
Do you have any questions related to Holoxan 1gm Injection ?

FAQs

Q. What is ifosfamide with mesna?

Ifosfamide may cause damage to urinary bladder therefore it is used in combination with mesna to prevent bleeding and inflammation of the urinary bladder (hemorrhagic cystitis).

Q. Does Holoxan cause hair loss or a vesicant?

Yes, Holoxan may cause hair loss and it may act as vesicant

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1683-84.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 688-90.
  3. Ifosfamide. Deerfield, Illinois: Baxter Healthcare Corporation; 1988 [revised Mar. 2012]. [Accessed 29 Jan. 2019] (online) Available from:External Link
  4. Drugs.com. Ifosfamide Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Ifosfamide. Deerfield, Illinois: Baxter Healthcare Corporation. [Accessed 26 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
A licensed pharmacy from your nearest location will deliver Holoxan 1gm Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹315.11
MRP393.89  Get 20% OFF
This price is valid only on the orders above ₹500
1 Injection in 1 vial
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