food interaction for HOLOXAN

alcohol interaction for HOLOXAN

pregnancy interaction for HOLOXAN

lactation interaction for HOLOXAN

There is no data available. Please consult doctor before consuming the drug.
Holoxan 100mg/2gm injection may cause excessive drowsiness and calmness with alcohol.
Holoxan 100mg/2gm injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Holoxan 100mg/2gm injection is probably unsafe to use during breastfeeding. Please consult your doctor.




Mesna is used to prevent ifosfamide-induced hemorrhagic cystitis
It is not for use to reduce the risk of blood in the urine due to other medical conditions.

How it works

Mesna helps to reduce the risk of inflammation and bleeding in the bladder, who receive ifosfamide (a medicine used to treat cancer).

Common side effects

Nausea, Headache, Lightheadedness, Lethargy, Abdominal pain, Flushing (sense of warmth in the face, ears, neck and trunk), Diarrhoea, Rash, Fever, Flu-like symptoms.


Ifosfamide is used in the treatment of blood cancer, breast cancer, non-small cell lung cancer and ovarian cancer.

How it works

Ifosfamide works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Common side effects

Nausea, Vomiting, Anemia, Hair loss, Decreased white blood cell count, Infection, Blood in urine, Cns toxicity.


No substitutes found

Top Medical Oncologists

Expert advice FOR HOLOXAN

  • Drink at least 1 litre of fluid daily while you are receiving mesna.
  • Seek immediate medical attention if you experience severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking mesna.
  • Do not drive or operate machinery as mesna may cause drowsiness, dizziness, blurred vision, or light headedness.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • You will be monitored for blood or protein in urine during the treatment of mesna.
  • Do not take if allergic to mesna or any of its ingredients (thiol containing compound)

Frequently asked questions FOR HOLOXAN


Q. Why it is given with ifosamide or cyclophosphamise (Cytoxan)?
It is given along with the chemotherapy drug ifosfamide or cyclophosphamide to reduce the side effects of these drugs
Q. Is mesna compatible with potassium chloride and doxorubicin?
Yes, Mesna is compatible with potassium chloride and doxorubicin
Q. Is mesna a chemotherapy drug?
Mesna is not a chemotherapy drug
Show More
Q. Is mesna cytotoxic?
No. Mesna is not cytotoxic drug. It is cytoprotective drug
Q. Is mesna a vesicant?
No, mesna is not a vesicant.


Q. What is ifosfamide with mesna?
Ifosfamide may cause damage to urinary bladder therefore it is used in combination with mesna to prevent bleeding and inflammation of the urinary bladder (hemorrhagic cystitis).
Q. Does ifosfamide cause hair loss or a vesicant?
Yes, ifosfamide may cause hair loss and it may act as vesicant


Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)