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HELIKIT TAB CAP.KIT 20MG/500MG/750MG TABLET

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Composition FOR HELIKIT TAB CAP.KIT

Omeprazole(20 mg),Tinidazole(500 mg),Amoxicillin(750 mg)

food interaction for HELIKIT TAB CAP.KIT

alcohol interaction for HELIKIT TAB CAP.KIT

pregnancy interaction for HELIKIT TAB CAP.KIT

lactation interaction for HELIKIT TAB CAP.KIT

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Helikit tab cap.kit 20mg/500mg/750mg tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.
UNSAFE
Helikit tab cap.kit 20mg/500mg/750mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR HELIKIT TAB CAP.KIT

Omeprazole(20 mg)

Uses

Omeprazole is used in the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers.

How it works

Omeprazole lowers the acid production in the stomach.

Common side effects

Nausea, Abdominal pain, Diarrhoea, Constipation, Flatulence
Tinidazole(500 mg)

Uses

Tinidazole is used in the treatment of bacterial infections
It is used in infections of the brain, reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body.

How it works

Tinidazole is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging the DNA.

Common side effects

Nausea, Headache, Dry mouth, Metallic taste
Amoxicillin(750 mg)

Uses

Amoxicillin is used in the treatment of bacterial infections

How it works

Amoxicillin is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Nausea, Allergic reaction, Vomiting, Diarrhoea

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Expert advice FOR HELIKIT TAB CAP.KIT

  • Take Omeprazole immediately before a meal, preferably in the morning.
  • Take Omeprazole for the entire duration of the treatment, even if you begin to feel better.
  • Get a blood test done to know the magnesium level in your body once a year; you may need a magnesium supplement while using the Omeprazole,as a long-term treatment.
  • Long-term use of the Omeprazole can cause weak or broken bones.
  • Avoid using clopidogrel (blood thinner) with Omeprazole.

Frequently asked questions FOR HELIKIT TAB CAP.KIT

Omeprazole

Q.

What is omeprazole?
Omeprazole belongs to the group of medicines known as proton pump inhibitors (PPIs). This drug decreases the acid production in your stomach and is indicated for the treatment of conditions caused by excess acid secretion in the stomach.

Q.

What is omeprazole used for?
Omeprazole is used to treat and prevent duodenal ulcers, stomach ulcers and ulcers caused by the non-steroidal anti-inflammatory drug (NSAIDs; pain killers) and along with antibiotics for the treatment of stomach ulcers infected with a bacteria known as Helicobacter pylori. Omeprazole is also indicated for the treatment of reflux oesophagitis, symptomatic gastro-oesophageal reflux disease (GERD) and Zollinger-Ellison syndrome.

Q.

How does omeprazole work?
Proton (acid) pumps are found on the stomach mucosa and they are responsible for secreting acid in the stomach. Omeprazole works by blocking this gastric acid pump and this unique mechanism of action helps in decreasing the acid secretion in the stomach.

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Q.

Is omeprazole available without a prescription as an over the counter product?
Omeprazole is a prescription medicine and you can buy this drug by providing a doctor's prescription. Omeprazole is not available as an over the counter (OTC) product.

Q.

Who can take omeprazole?
Adults and children more than 1 year of age and more than 10 kg in weight can take omeprazole.

Q.

When and how should I take omeprazole?
Omeprazole capsules or tablets should be taken once a day in the morning preferably empty stomach at least half to one hour before breakfast. Swallow your medicine whole with minimum half a glass of water. Do not chew or crush the tablets or capsules.

Q.

What foods should be avoided while taking omeprazole?
You should preferably avoid taking foods that cause acidity and heartburn when you are taking omeprazole as these foods would aggravate your disease condition, for example: foods that are fried, prepared in butter or oil, fat rich foods, tomato-based foods and juices, caffeinated drinks like cola, tea, drinks from citrus fruits like lemon water or orange juice and alcohol-containing drinks.

Q.

How long does it take for omeprazole to start working?
Omeprazole may start to work on the first day of taking it, however, it may take 3 to 4 days to achieve its full effect. You may need to add another acid-lowering drug for relief in the initial few days.

Q.

For how long can omeprazole be taken?
Take omeprazole for as long as advised by your doctor. The duration of taking omeprazole would vary depending on your condition. You may be asked to take this drug for 2 weeks for healing of your duodenal ulcers, 4 weeks for stomach ulcers and 4 to 8 weeks for GERD symptoms and for ulcers caused by NSAIDs. Do not stop taking this medicine without talking to your doctor.

Q.

Where does omeprazole gets absorbed in the body?
Omeprazole gets absorbed in the small intestine.

Q.

How is omeprazole metabolised in the body?
Omeprazole is metabolized in the liver by the cytochrome P450 enzymes mainly CYP2C19. There could be an increase in the level of omeprazole in patients with underlying liver disease because of a decrease in its metabolism. However, the amount of drug does not increase if given once a day.

Q.

How long does omeprazole stay in the body?
Omeprazole stays in the body for almost 72 hours after stopping the medicine. Omeprazole is removed from the body through the urine.

Q.

What are the various conditions in which the use of omeprazole is contraindicated?
Use of omeprazole is contraindicated if you are allergic to this medicine or any other medicine belonging to the same class of drugs. Also, do not take omeprazole if you are already taking a medicine containing nelfinavir (used for the treatment of HIV infection).

Q.

Can omeprazole cause calcium deficiency and osteoporosis?
Omeprazole can cause calcium deficiency and hence an increased risk of bone fractures on long term use. Normally the acidic environment of the stomach helps in the release of ionized calcium from insoluble calcium salts, which is important for calcium absorption. As omeprazole causes a decrease in the gastric acid levels, so it can decrease calcium absorption and increase the risk of bone fractures.

Q.

Can omeprazole cause magnesium deficiency?
Omeprazole can cause magnesium deficiency in the blood. Low magnesium levels is a rare side effect seen in patients treated with omeprazole for at least three months and in most cases after a year of therapy. The patient may have symptoms like tetany, arrhythmias, and seizures and may need to stop this medicine and take magnesium from outside. Magnesium levels should be tested at regular intervals in the patients taking omeprazole for a long duration.

Q.

Does omeprazole cause iron deficiency?
Use of omeprazole can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking omeprazole.

Q.

Does omeprazole cause vitamin deficiencies?
Omeprazole may cause vitamin B12 and vitamin C deficiency. When taken orally, vitamin B12 requires an acidic environment for its absorption from the stomach while omeprazole causes a decrease the gastric acid secretion. You may need to take vitamin B12 supplements from outside. The clinical significance of the decrease in vitamin C levels is not known, so vitamin C supplementation is not recommended.

Q.

Can omeprazole cause lactose intolerance?
Lactose intolerance has been reported with the use of omeprazole in some patients. Many omeprazole preparations contain lactose as an ingredient. This is a digestive problem in which the patient cannot digest lactose, a type of sugar mainly found in milk and dairy products. The patient may complain of symptoms like flatulence (gas), diarrhea, bloating, stomach pain and feeling of being sick (nausea). Read the ingredients mentioned on the pack before taking the medicine.

Q.

Does omeprazole contain gelatin?
Omeprazole does not contain gelatin as one of its constituent. However, in the capsule dosage form of omeprazole, the outer capsule that contains the medicine is made up of gelatin.

Q.

Can I take omeprazole with alcohol?
Omeprazole can be taken with alcohol as no harmful effects have been reported. However, alcohol intake can cause higher acid secretion, hence decreasing the acid lowering effect of omeprazole. Also, omeprazole can make some people feel dizzy or sleepy, adding to the sedative effects of alcohol and they may find it difficult to drive or operate a machine.

Q.

Can I take omeprazole during pregnancy?
Omeprazole may be unsafe to take during pregnancy. There is limited data available from humans, however, animal studies have shown harmful effects of omeprazole use on the foetus (unborn baby). Talk to your doctor if you are pregnant or planning to have a baby before taking omeprazole as your doctor would be able to advise you better on the basis of your underlying health condition.

Q.

Can I take omeprazole during lactation?
Omeprazole passes (excreted) into the breast milk but is not likely to cause any harmful effects to the child when taken in doses as advised. Your doctor can help you decide whether you should take omeprazole during breastfeeding (lactation) or not.

Q.

What if I miss my dose of omeprazole?
If you miss a dose of omeprazole, take it as soon as you remember and the next dose as scheduled. However, if it is almost the time for your next dose, skip the missed dose and take your next dose and then follow the regular schedule. Do not take double the dose.

Q.

Can omeprazole affect my driving?
Omeprazole is not likely to affect your ability to drive or use machines. However, omeprazole can cause dizziness and visual disturbances, so, you may need to be careful while driving or operating any machinery if you experience these symptoms.

Q.

How do I store omeprazole?
Store omeprazole below 25°C (between 15°C and 30°C). Keep in a cool and dark place in the original pack.

Q.

Does omeprazole have an expiry date?
Yes, omeprazole does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use omeprazole after the expiry date.

Q.

Is omeprazole a narcotic substance?
Omeprazole is a not a narcotic substance and has not been reported to have any abuse potential. Omeprazole does not get you high and does not cause any addiction as no withdrawal symptoms have been reported when you stop taking this drug.

Q.

Is omeprazole a controlled substance?
Omeprazole is not a controlled substance. It is available when prescribed by a doctor.

Q.

What are the side effects of using omeprazole?
The most common side effects seen with the use of omeprazole are a headache, diarrhea, constipation, flatulence (gas), bloating, stomach pain (abdominal pain), feeling sick (nausea) or being sick (vomiting), non-cancerous (benign) growths in the stomach. A few uncommon side effects are skin rash, lumpy rash (hives), itchy skin, generally feeling unwell and lacking energy, swelling of the feet and ankles, disturbed sleep (insomnia), dizziness, tingling feelings such as “pins and needles”, feeling sleepy, spinning feeling (vertigo), changes in liver function tests.

Q.

What are the rare side effects of omeprazole?
Rare side effects seen with the use of omeprazole are decrease in white cells or platelets causing weakness, bruising or infections more common. Allergic reactions with swelling of the lips, tongue and throat, fever, wheezing, low levels of sodium in the blood, agitation, confusion or depression, taste changes, eyesight problems like blurred vision, wheezing, shortness of breath (bronchospasm), dry mouth, thrush, liver problems like jaundice, hair loss (alopecia), skin rash on exposure to sunshine, joint pains (arthralgia) or muscle pains (myalgia), severe kidney problems (interstitial nephritis), increased sweating, inflammation of the gut causing diarrhoea

Q.

Does omeprazole cause hepatitis B and can a patient of hepatitis take omeprazole?
Omeprazole can rarely cause hepatitis with or without jaundice and very rarely it can lead to hepatic failure and encephalopathy in patients with the underlying liver disease. Omeprazole does not cause hepatitis B or any other viral hepatitis. However, there are studies showing an increased occurrence of hepatic encephalopathy in hepatitis B patients using PPIs. These medicines should be used with caution in patients with the underlying liver disease.

Q.

Does omeprazole use increase the risk of clostridium difficile infection?
Use of proton pump inhibitors (PPIs) like omeprazole may be associated with an increased risk of Clostridium difficile–associated diarrhea (CDAD) as reported in few studies and informed by the US FDA as well. A possibility of CDAD can be there in patients taking PPIs and developed diarrhea that does not improve.

Q.

Can I take omeprazole along with oral contraceptive pills (birth control pills)?
Omeprazole can be safely taken with oral contraceptive pills (birth control). They do not affect each other's action and no harmful effects have been seen when they are used together.

Q.

Can I take omeprazole with Vitamin E?
Omeprazole can be taken with vitamin E. The combinations seems to have a beneficial effect in terms of better maintenance of moderate to severe esophagitis. However, there are not many studies or reports on this subject. Talk to your doctor for more information on this.

Q.

Can omeprazole cause subacute cutaneous lupus erythematosus?
Omeprazole has been reported to cause subacute cutaneous lupus erythematosus in many studies. Common signs and symptoms of this disease include painful joints, tiredness, weakness, rash, fever, anemia, mouth ulcers, hair loss, and many others and these may get aggravated again and again. Talk to your doctor if you experience these side effects as you may need to discontinue this medicine.

Q.

Does omeprazole increase chromogranin levels?
Use of proton pump inhibitors like omeprazole has been seen to be associated with an increase in chromogranin levels. This increase in chromogranin levels can be due to the effect of these drugs on enterochromaffin cells and this could also falsely increase the levels in patients with neuroendocrine tumours.

Q.

Does omeprazole cause dementia?
Use of proton pump inhibitors like omeprazole has been recently linked with the development of dementia in elderly patients. As this risk of developing dementia is not confirmed, talk to your doctor for more information on this effect.

Tinidazole

Q.

Is tinidazole or Fasigyn an antibiotic/sulfa drug?
Tinidazole is an antibiotic/anti-protozoal/anti-amoebic drug. It is not a sulfa drug

Q.

Is tinidazole available or sold over the counter?
No. Tinidazole is a prescription drug. It is not available or sold over the counter

Q.

Is tinidazole the same as metronidazole/Flagyl?
Tinidazole is different from metronidazole (also called as Flagyl). However, both of them belong to the same class of drugs

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Q.

Is tinidazole/Fasigyn safe?
Yes. Tinidazole is relatively safe if used as recommended. In case of any side-effects, consult your doctor

Q.

What are Tiniba and Fasigyn used for?
Tiniba and Fasigyn are brand names of tinidazole available in the market. They are used for the same indications as tinidazole

Q.

Can I take tinidazole with fluconazole/Tylenol/ibuprofen?
Tinidazole can be taken with fluconazole/Tylenol (paracetamol)/ibuprofen only if prescribed by your doctor

Q.

Does tinidazole cure bacterial vaginosis and UTI?
Tinidazole is effective in the treatment of bacterial vaginosis. But it is not used for treatment of UTI

Q.

Does tinidazole cause yeast infections/diarrhea/cancer?
Prolonged use of tinidazole may cause candida or yeast infections. There is no evidence of tinidazole causing cancer. If you experience any such symptoms, please consult your doctor

Q.

Does tinidazole treat Chlamydial or urinary tract infections?
Yes. Tinidazole is used to treat Chlamydial infections, but is not effective for treating a urinary tract infection

Q.

Does tinidazole affect birth control?
There is no evidence of tinidazole affecting birth control. Please consult your doctor to confirm whether you require a secondary birth control measure while taking tinidazole.

Amoxicillin

Q.

Does amoxicillin act against anaerobic bacteria?
Amoxicillin is active against aerobic (both gram-positive and gram-negative) bacteria and anaerobic bacterial infections like clostridium sp.

Q.

Does amoxicillin cause fungal (yeast) infections?
Amoxicillin is a broad spectrum antibiotic. On long-term use, it may kill helpful bacteria in the body which keep the body’s fungal (yeast) population in check. So, this decrease in the number of helpful bacteria may lead to fungal (yeast) infections.

Q.

Can I take amoxicillin for virus infections?
Amoxicillin is only effective against bacterial infections, not viral infections. Consult a doctor before taking any antibiotics.

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Q.

Does amoxicillin cause constipation?
Amoxicillin has not been reported to cause constipation. However, consult your doctor if you have constipation while taking amoxicillin as this could be due to some other underlying condition.

Q.

Does amoxicillin cause headache?
Amoxicillin has not been reported to cause a headache. However, consult your doctor if you have a headache while taking amoxicillin as this could be due to some other underlying condition.

Q.

Is amoxicillin gluten free?
Yes, amoxicillin is gluten free.

Q.

Can I take amoxicillin for fever?
Amoxicillin can be used in the treatment of fever only if it is associated with an infection which can be treated with it. Talk to a doctor for the right diagnosis of your condition before taking any antibiotics.

Q.

Can I take amoxicillin for boils?
Amoxicillin is effective in the treatment of skin and soft tissue infections like boils. However, talk to a doctor for the right antibiotics for your infections.

Q.

Can I take amoxicillin for a sore throat?
Amoxicillin can be used in the treatment of sorethroat only if it is associated with an infection which can be treated with it. Talk to a doctor for the right diagnosis of your condition before taking any antibiotics.

Q.

Can I take amoxicillin for bacterial vaginosis?
Amoxicillin can be used in the treatment of bacterial vaginosis. However, talk to a doctor before taking any antibiotics for your condition.

Q.

Can I take amoxicillin for flu?
Amoxicillin is not useful for the treatment of flu. Consult a doctor for knowing the right medicines for its treatment.

Q.

Can I take amoxicillin for an ear infection?
Amoxicillin can be used for the treatment of ear infection, however, talk to a doctor for the right antibiotics for your infections.

Q.

Can I take amoxicillin for diverticulitis?
Amoxicillin can be used in the treatment of diverticulitis, however, talk to a doctor for the right antibiotics for your condition.

Q.

Is amoxicillin safe?
Amoxicillin is safe to use if taken at prescribed doses for the prescribed duration as advised by a doctor.

Q.

Is amoxicillin safe for heart patients?
Amoxicillin is safe to use in heart patients if used at prescribed doses for the prescribed duration as advised by the doctor. Always share your medical history with the doctor before taking any medicine.

Q.

Is amoxicillin used for throat infections?
Amoxicillin can be used for the treatment of throat infections. However, it should be used when the cause of infection is diagnosed by the doctor and amoxicillin is recommended for its treatment.

Q.

Is amoxicillin a pain killer?
Amoxicillin is not a pain killer. It is an antibiotic.

Q.

Is amoxicillin a cephalosporin?
Amoxicillin is not a cephalosporin. It is an antibiotic which belongs to a class of drugs known as penicillins.

Q.

Is amoxicillin good for prostate infection?
Amoxicillin can be used for treating prostate infections caused by bacteria against which it is active. Consult a doctor for the right diagnosis of your infection and use antibiotics which are recommended.

Q.

Does amoxicillin treat urinary tract infection (UTI)?
Yes, amoxicillin can be used to treat urinary tract infection (UTI) if it is caused by the bacteria against which amoxicillin is active. Consult a doctor for the right diagnosis of your infection and use antibiotics which are recommended.

Q.

Does amoxicillin contain sulfa?
No, amoxicillin does not contain sulfa. It is an antibiotic which belongs to a class of medicines known as penicillins.

Q.

Does amoxicillin can treat cough?
Amoxicillin would be needed for the treatment of a cough only if it is associated with an infection. Talk to a doctor for the right diagnosis of your condition before taking any antibiotics.

Q.

Does amoxicillin cause drowsiness?
No, amoxicillin has not been reported to cause drowsiness. In case you experience drowsiness while taking amoxicillin, please consult your doctor.

Q.

Does amoxicillin affect sperm?
No, amoxicillin has not been reported to affect sperm. Please consult your doctor.

Q.

Does amoxicillin contain penicillin?
Amoxicillin does not contain penicillin. However, it belongs to the same class of antibiotics.

Q.

Does amoxicillin cause diarrhea in babies?
Amoxicillin can cause diarrhea as a common side effect in babies as well as adults. In case you have diarrhea, it could be due to the change in the normal bacteria in the gut and you may need to stop the medicine. Do not stop any medicine without consulting your doctor.

Q.

Does amoxicillin decrease milk secretion?
No, amoxicillin has not been reported to decrease milk secretion. Please consult your doctor if you are breast-feeding before taking the medicine.

Q.

Does amoxicillin cause diarrhea?
Amoxicillin can cause diarrhea as a common side effect. Please talk to your doctor in case you have this side effect as it could be due to the change in the normal bacteria of your gut and you may need to stop this medicine.

Q.

Can I take amoxicillin with milk?
Amoxicillin capsules should be swallowed with water. However, they can be taken before, during or after your meals.

Q.

Can I take amoxicillin with tramadol?
Amoxicillin can be taken with tramadol. No drug-drug interactions have been seen between the two. However, interactions cannot occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take amoxicillin with food?
Yes, amoxicillin can be taken with food. Amoxiciilin capsules should be swallowed with water.

Q.

Can I take amoxicillin with yogurt?
Yes, amoxicillin can be taken with yogurt. Amoxicillin capsules should be swallowed with water.

Q.

Can I take amoxicillin with metronidazole?
Amoxicillin can be taken with metronidazole. No drug-drug interactions have been clinically seen between the two. However, interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take amoxicillin with medicine for a cold?
Please consult your doctor before taking amoxicillin with any medicine for cold as these medicines have many components and the interaction with each component can be different.

Q.

Can I take amoxicillin with metformin?
Yes, amoxicillin can be taken with metformin. No drug-drug interactions have been seen between the two. However, this does not mean that interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take amoxicillin with loratadine?
Yes, amoxicillin can be taken with loratadine. No drug-drug interactions have been seen between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take amoxicillin with aspirin?
Amoxicillin and aspirin increase levels of each other. Please consult your doctor before taking amoxicillin with aspirin at the same time.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)