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Composition for HARMLESS

Colistimethate(125 mg)

food interaction for HARMLESS

alcohol interaction for HARMLESS

pregnancy interaction for HARMLESS

lactation interaction for HARMLESS

It can be taken with or without food, but it is better to take Harmless 125mg syrup at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Harmless 125mg syrup may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Colistimethate(125 mg)


Harmless 125mg syrup is used to treat chronic chest infections due to bacteria Pseudomonas aeruginosa in patients with cystic fibrosis (genetic disorder of glands resulting in lung and digestive problems).

How it works

Harmless 125mg syrup belongs to group of medicines called polymyxin antibiotic drugs. It acts by binding to the bacterial cell wall and changing its permeability, causing bacterial cell death.

Common side effects

Numbness of tongue, Decreased urination, Allergic reaction, Itching, Application site irritation, Chest tightness, Diarrhoea, Fever, Dizziness, Shortness of breath, Muscle weakness, Stomach upset


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Expert advice for HARMLESS

  • Consult your doctor if you have any of the following medical conditions: kidney disease, myasthenia gravis (neuromuscular disease characterized by very weak muscles and unusual tiredness), porphyria (a rare blood pigment disorder that affects skin and other organs) or asthma (difficulty in breathing).
  • Caution should be taken in premature and new-born babies as the kidneys are not fully developed or in children younger than 10 years of age who have diarrhea or an infection of the stomach or bowel.
  • Do not drive or operate heavy machinery because you may feel sleepy or dizzy while being treated with colistimethate.
  • Do not consume alcohol while taking colistimethate as it may worsen the side effects.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.


Content on this page was last updated on 05 October, 2014, by Dr. Varun Gupta (MD Pharmacology)