Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gpm 1 Tablet SR is to be taken with food. Gpm 1 Tablet SR may cause stomach upset if taken empty stomach.
Gpm 1 Tablet SR is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
WEIGH RISKS VS BENEFITS
Gpm 1 Tablet SR may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Gpm 1 Tablet SR is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby. Monitor the breastfed baby’s blood sugar during treatment with Gpm 1 Tablet SR
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Gpm 1 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Gpm 1 Tablet SR may be needed. Please consult your doctor. Use of Gpm 1 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Gpm 1 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Gpm 1 Tablet SR may be needed. Please consult your doctor. Use of Gpm 1 Tablet SR is not recommended in patients with severe liver disease.
“The following are the results of on-going survey on 1mg.com for Gpm 1 Tablet SR. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”
Information last updated by Dr. Varun Gupta, MD Pharmacology on 27th Mar 2018.