Glycolate 0.2mg Injection

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Glycolate 0.2mg Injection is an anticholinergic medication. It is used before or even during an operation to reduce secretions and it even reverses the unwanted effects of certain medicines used during surgery (muscle relaxants). It also helps to treat peptic ulcers when oral medication is not tolerated.

Glycolate 0.2mg Injection is given by your doctor or nurse. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

The most common side effects of this medicine include dry mouth, urinary retention, blurred vision, photophobia, dilation of the pupil, cycloplegia, ocular hyperemia, tachycardia, bradycardia, palpitation, and reduced sweating. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Inform your doctor if you have glaucoma, myasthenia gravis, heart failure, and high blood pressure.

Uses of Glycolate Injection

Benefits of Glycolate Injection

In General Anaesthesia

Glycolate 0.2mg Injection is used before and during surgery to reduce secretions of the mouth, throat, or stomach, such as saliva, stomach acid, or to prevent problems related to heart rhythm during anesthesia, intubation, or surgery. It also helps decrease the unwanted effects that may be caused by certain medicines like, neostigmine, pyridostigmine, etc. It is given by a specialist doctor called an anesthetist in a hospital setup.

In Peptic ulcer disease

Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Glycolate 0.2mg Injection reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer.

Side effects of Glycolate Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glycolate

  • Urinary retention
  • Blurred vision
  • Dilatation of pupil
  • Cycloplegia (paralysis of the ciliary muscle of the eye)
  • Ocular hyperemia
  • Slow heart rate
  • Palpitations
  • Reduced sweating

How to use Glycolate Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Glycolate Injection works

Glycolate 0.2mg Injection is an anticholinergic medication. It works by blocking the activity of a chemical messenger (acetylcholine) in the brain. This helps dry up secretions (saliva, stomach acid etc.) from glands before surgery, increases a low heart rate and reverses the unwanted effects of certain medicines used during surgery (muscle relaxants and anaesthetics). By lowering stomach acid content, it also helps treat peptic ulcers.

Safety advice

It is not known whether it is safe to consume alcohol with Glycolate 0.2mg Injection. Please consult your doctor.
Glycolate 0.2mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
Glycolate 0.2mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Long-term use of Glycolate 0.2mg Injection might reduce milk production.
Glycolate 0.2mg Injection may cause side effects which could affect your ability to drive.
Glycolate 0.2mg Injection may affect vision and coordination. This may affect your driving ability.
Glycolate 0.2mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Glycolate 0.2mg Injection may be needed. Please consult your doctor.
There is limited information available on the use of Glycolate 0.2mg Injection in patients with liver disease. Please consult your doctor.

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Quick tips

  • Glycolate 0.2mg Injection is used before an operation, to reduce saliva and other secretions and to make the stomach contents less acidic.
  • It may also be used to reduce side effects of muscle-relaxing drugs and to prevent of slowing of heart beat during surgery.
  • It is given as an injection into a muscle or into a vein. 
  • Use caution while driving or doing anything that requires concentration as Glycolate 0.2mg Injection may cause dizziness and blurred vision.

Fact Box

Chemical Class
Synthetic Quaternary Ammonium
Habit Forming
Therapeutic Class
Action Class
Anticholinergic - Anaesthesia

Patient concerns

I have hyperhydrosis. Especially in my face. Please tell me the safe treatments And also the cost related to various treatments.
Dr. Vikas Sharma
Try glycolate 1 mg tds
I am suffering from stomach problems from last 2 months regularly.This is my ultrasound report.Please explain this report in simple words.
Dr. Pushkar Mani
U having fatty liverAnd probably peptic ulcer

User feedback


Q. Is Glycolate 0.2mg Injection a narcotic?

No, Glycolate 0.2mg Injection is not a narcotic. It is given before surgery to reduce secretions in the mouth, throat, airways, and stomach. Doing this will reduce the formation of saliva and other secretions and ease the operation. Glycolate 0.2mg Injection is also given before or during the surgery, to prevent slowness of the heart beat during surgery.

Q. Does Glycolate 0.2mg Injection cause tachycardia?

Yes, Glycolate 0.2mg Injection has its action on the heart which increases the heart rate (tachycardia). This property of the medication is utilized during surgery to prevent the fall of heart rate due to various other supplemental anesthetic medications.

Q. Can Glycolate 0.2mg Injection cause constipation?

Yes, Glycolate 0.2mg Injection can cause constipation because of its action on the intestine. It decreases the intestinal secretions and also decreases the gut motility which can result in constipation.

Q. Does Glycolate 0.2mg Injection increase blood pressure?

Yes, Glycolate 0.2mg Injection can sometimes lead to an increase in blood pressure. There are evidences where it has led to increased blood pressure. Therefore, when injected into a patient during a surgery, the heart rate and blood pressure are continuously monitored.

Q. I am on antidepressants currently. Can I take Glycolate 0.2mg Injection?

No, some classes of antidepressant medicines can worsen the side effects of Glycolate 0.2mg Injection and cause uneasiness for the patient. These antidepressant medicines may include tricyclic antidepressants (amitriptyline or imipramine), phenelzine, tranylcypromine, clozapine, etc. Therefore, do inform your doctor about your previous illness and the medicines you are taking before you take this medication. Your doctor may make the necessary adjustments.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Glycopyrrolate. Berlin, Germany: B. Braun Melsungen AG; 2018. [Accessed 28 Mar. 2019] (online) Available from:External Link
  2. Glycopyrrolate Pregnancy and Breastfeeding Warnings. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Glycopyrrolate. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:External Link

Manufacturer/Marketer address

12, R. C. Patel Industrial Estate, Akota, Baroda - 390 020., INDIA
Country of origin: India

Expires on or after: August, 2022

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