Glioz 250mg Tablet

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Dr Reddy's Laboratories Ltd

Composition for Glioz 250mg Tablet

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Primarily used for

Potentiallyunsafewith
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Pregnancy
21764.9
₹4352.98/Tablet
5 tablets in 1 strip
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Medicine Overview of Glioz Tablet

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Uses of Glioz Tablet

Glioz 250mg Tablet is used in the treatment of Brain tumor.
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Side effects of Glioz Tablet

Common

Nausea, Headache, Vomiting, Weakness, Loss of appetite, Fatigue, Hair loss, Viral infection, Convulsion, Insomnia (difficulty in sleeping), Fever, Decreased white blood cell count, Reduced blood platelets, Coordination disorder, Diarrhoea, Dizziness, Constipation, Rash, Decreased white blood cell count (neutrophils), Decreased white blood cell count (lymphocytes), Hemiparesis (weakness on one side of the body), Memory loss.

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How to use Glioz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It is better to take Glioz 250mg Tablet empty stomach (1 hour before food or 2 hours after food).

How Glioz Tablet works

Glioz 250mg tablet works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

In Depth Information on Glioz Tablet

Expert advice for Glioz Tablet

  • Swallow full tablets on an empty stomach, one hour before your meal.
  • Avoid being near people who are sick or have infections. Consult your doctor if you develop symptoms of opportunistic infections (such as Pneumocystis jirovecii pneumonia) and reactivation of infections (such as hepatitis B virus) Using temozolomide may increase your risk of developing certain types of bone marrow cancer. Be aware about your specific risk.
  • You may be given medication to prevent nausea or other side effects while you are receiving temozolomide.
  • Your blood will be tested frequently during treatment to monitor the side effects of temozolomide on your blood cells as you may have a small risk of other changes in blood cells, including leukemia.
  • Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
  • Do not drink alcohol while taking temozolomide.
  • Do not drive or operate machinery while using temozolomide as it may make you tired or sleepy.
  • Both male and female patients should take effective contraceptive precautions during and after 6 months of treatment. Male patients should seek advice on conservation of sperm prior to treatment as temozolomide treatment may cause infertility.
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Warnings
Special precautions for Glioz 250mg Tablet
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
WEIGH RISKS VS BENEFITS
Glioz 250mg Tablet is unsafe to use during pregnancy.

There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
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Lactation
Glioz 250mg Tablet is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
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Driving
Glioz 250mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.

Caution is advised when driving or operating machinery.
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Kidney
SAFE
Glioz 250mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Glioz 250mg Tablet is recommended.

Caution should be used in patients with renal impairment.
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Liver
There is no data available. Please consult doctor before consuming the drug.

Missed Dosageuses

If you miss a dose of Temozolomide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Glioz 250mg Tablet

Frequently asked questions for Temozolomide

Glioz is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. It is used to treat specific types of brain tumor. It is a radiosensitizer
Glioz is effective and works for patients if taken at recommended dosage and duration as recommended by the doctor
Glioz is given as a capsule and is taken by mouth. It should be administered in the fasting state, at least one hour before meal. It is rapidly metabolized at physiologic pH to the active monomethyl triazenoimidazole carboxamide (MTIC). The half-life (t1/2) in plasma is approximately 1.8 hours
Glioz because of its small size and lipophilic properties is able to cross the blood-brain barrier rapidly and is present in the cerebrospinal fluid
Hair loss is a side effect of using Glioz. Always follow doctor's advice regarding its use
Glioz is a FDA approved drug.
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