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MDS (Oral Pathology & Microbiology), BDS
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MD (Pharmacology), MBBS
Last updated on:
14 May 2019 | 02:46 PM (IST)
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Glimfirst MV 2 Tablet SR


Overview

Introduction

Glimfirst MV 2 Tablet SR is used in the treatment of type 2 diabetes. It is a combination of two medicines that effectively control blood sugar levels, when a single medication is not effective. It should be used along with proper diet and regular exercise for best results. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level).

Uses of Glimfirst MV Tablet SR

Glimfirst MV Tablet SR side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Nausea
  • Diarrhea
  • Taste change
  • Flatulence
  • Stomach pain
  • Headache
  • Skin rash
  • Respiratory tract infection

How to use Glimfirst MV Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glimfirst MV 2 Tablet SR is to be taken with food.
Glimfirst MV 2 Tablet SR may cause stomach upset if taken on empty stomach.

How Glimfirst MV Tablet SR works

Glimfirst MV 2 Tablet SR is a combination of three antidiabetic medicines: Glimepiride, metformin and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Voglibose is an alpha-glucosidase inhibitor which prevents breakdown of complex sugars into simple sugars such as glucose. This prevents the blood glucose levels from rising to very high levels after meals.

Glimfirst MV Tablet SR related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Glimfirst MV 2 Tablet SR. Taking Voglibose with alcohol reduce the blood sugar levels in diabetic patients.
Pregnancy
WEIGH RISKS VS BENEFITS
Glimfirst MV 2 Tablet SR may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Glimfirst MV 2 Tablet SR is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Glimfirst MV 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Glimfirst MV 2 Tablet SR may be needed. Please consult your doctor.
Use of Glimfirst MV 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Glimfirst MV 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Glimfirst MV 2 Tablet SR may be needed. Please consult your doctor.
Glimfirst MV 2 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Glimfirst MV 2 Tablet SR
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Expert Advice

  • Take it with food to lower your chance of having an upset stomach.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Carry a sugar source with you for immediate relief.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to Glimfirst MV

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My mom is diabetic from last 13 years. She is on medicine and having type 2 diabetes. Currently she is taking below medicine - amaryl m2, galvusmet 50/500, forxiga-10. But from last week her sugar level is increasing and now reaches to 250 fasting. Could you please recommend me ayurvedic medicine that will keep sugar level in control and keep her energitic. Thanks
Dr. Manju Singh
Psychiatrist
Please consult with Ayurvedic doctor nearest to your home.
I have type-2 Diabetes taking trivolib1 And glisen mf 1 Two times a day.before meal.but.my sugar not controlled my.fbs sugar-236 And pp2bs.is 356 Pl,advisr what to do
Dr. Ila Jain Khandelwal
Pathologist
Hi I suggest you should consult your diabetologist or general practitinoer He will see all your previous records and review your treatment
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User Feedback


FAQs

Q. What is Glimfirst MV?

Glimfirst MV is a combination of three medicines: Glimepiride, Metformin and Voglibose. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Voglibose is an alpha-glucosidase inhibitor which lowers the postprandial (after meals) glucose levels in the body. This combination is not indicated for the treatment of Type 1 DM.

Q. What are the possible side effects of Glimfirst MV?

The use of Glimfirst MV is associated with common side effects like hypoglycemia (low blood sugar level), nausea, diarrhea, altered taste, flatulence, stomach pain, headache, skin rash and respiratory tract infection.

Q. Are there any specific conditions in which Glimfirst MV should not be taken?

The use of Glimfirst MV should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also avoided in patients with moderate to severe kidney disease and in patients with inflammatory bowel disease, colonic ulcerations and underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Glimfirst MV?

No, it is not safe to take Glimfirst MV along with alcohol. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. Can the use of Glimfirst MV cause hypoglycemia?

Yes, the use of Glimfirst MV can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Q. What are the instructions for the storage and disposal of Glimfirst MV?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Metformin Hydrochloride (SR), Glimepiride & Voglibose. Dehradun, India: Windlas Biotech Private Limited; 2017. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Dabhi AS, Bhatt NR, Shah MJ. Voglibose: An Alpha Glucosidase Inhibitor. J Clin Diagn Res. 2013;7(12):3023-7. [Accessed 08 Apr. 2019] (online) Available from:External Link
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