Genxtor 25mg Injection

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Biocon

Composition for Genxtor 25mg Injection

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Primarily used for

Transplant rejection of kidney
51428.2
₹51428.2/Injection
1 Injection in 1 vial
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Medicine Overview of Genxtor Injection

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Uses of Genxtor Injection

Genxtor 25mg Injection is used in transplant rejection of kidney.
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Side effects of Genxtor Injection

Common

Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Reduced blood platelets, Increased heart rate, Decreased white blood cell count, Anemia, Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.

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How to use Genxtor Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Genxtor Injection works

Genxtor 25mg injection suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

In Depth Information on Genxtor Injection

Expert advice for Genxtor Injection

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
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Warnings
Special precautions for Genxtor 25mg Injection
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
WEIGH RISKS VS BENEFITS
Genxtor 25mg Injection may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
CAUTION
Genxtor 25mg Injection is probably usafe to use during lacta
tion. Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
SAFE
Genxtor 25mg Injection does not usually affect your ability to drive.
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Kidney
SAFE
Genxtor 25mg Injection is safe to use in patients with kidne
y disease. No dose adjustment of Genxtor 25mg Injection is recommended.
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Liver
Genxtor 25mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Genxtor 25mg Injection may be needed. Please consult your doctor.

Dose adjustment is not recommended in patients with mild to moderate liver disease.
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Severely interacts with other drugs like
Azivent 500mg Tablet, Zathrin Redimix Suspension, Pratham 200mg/5ml Suspension, Azifine 200mg/5ml Suspension

Patient Concerns

Frequently asked questions for Genxtor 25mg Injection

Frequently asked questions for Sirolimus

Genxtor is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Genxtor is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Genxtor is a cytotoxic agent
The Genxtor-eluting stent is a metal stent coated with 140 µg/cm2 of Genxtor blended with synthetic polymers. After stent implantation, Genxtor is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Genxtor causes hair loss
Genxtor alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
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Substitutes for Genxtor

No substitutes found for this medicine
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