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Genxtor 25mg Injection

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Composition for Genxtor 25mg Injection

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Primary uses of Genxtor 25mg Injection

Prevention of kidney transplant rejection
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Medicine Overview of Genxtor Injection

uses

Uses of Genxtor Injection

Genxtor 25mg Injection is used to prevent prevention of kidney transplant rejection.
uses

Genxtor Injection side effects

Common

Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Reduced blood platelets, Increased heart rate, Decreased white blood cell count, Anemia (low number of red blood cells), Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.

uses

How to use Genxtor Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Genxtor Injection works

Genxtor 25mg Injection suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

In Depth Information on Genxtor Injection

Expert advice for Genxtor Injection

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
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Genxtor Injection related warnings
Special precautions for Genxtor Injection
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Genxtor 25mg Injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Genxtor 25mg Injection is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
SAFE
Genxtor 25mg Injection does not usually affect your ability to drive.
Kidney
SAFE
Genxtor 25mg Injection is safe to use in patients with kidney disease. No dose adjustment of Genxtor 25mg Injection is recommended.
Liver
Genxtor 25mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Genxtor 25mg Injection may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.

Patient Concerns

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Frequently asked questions about Genxtor Injection

Frequently asked questions about Sirolimus

Genxtor is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Genxtor is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Genxtor is a cytotoxic agent
The Genxtor-eluting stent is a metal stent coated with 140 µg/cm2 of Genxtor blended with synthetic polymers. After stent implantation, Genxtor is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Genxtor causes hair loss
Genxtor alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
Severely interacts with other drugs like
Taking Genxtor with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Genxtor with Spiramycin
LIFE-THREATENING
Medicines with composition Spiramycin: Spiramycin, Macromycin, Spiratox
Genxtor with Clarithromycin
LIFE-THREATENING
Medicines with composition Clarithromycin: Clarimac, Klarim, Cloff, Clarital, Truclar, Claricin, Bioclar, Claribid, Clarie, C Cin
LIFE-THREATENING
Medicines with composition Rubella (German Measles): Rubella, R-VAC
Genxtor with Voriconazole
LIFE-THREATENING
Medicines with composition Voriconazole: Vosicaz, Vorizol, Voraze, Rextro, Vhope, Vonaz, Vocozo, Voritek, Voritrop, Vorifit, Vorzu
Genxtor with Varicella Vaccine
LIFE-THREATENING
Medicines with composition Varicella Vaccine: Biovac V
Genxtor with Erythromycin
LIFE-THREATENING
Medicines with composition Erythromycin: Althrocin, Eryster, Eryspic, Elthrocin, Etomin, Erythrocin, Erypal, Erythrokem, Agrocin, Eltocin, Eryspans
Genxtor with Rifampicin
LIFE-THREATENING
Medicines with composition Rifampicin: Monocin, Rifacept, R-Cin, Montomycin, Ticin
LIFE-THREATENING
Medicines with composition Rotavirus Vaccine Live Attenuated: Rotarix
Genxtor with Itraconazole
SERIOUS
Medicines with composition Itraconazole: Itrasig, Itracan, Candiforce, Canditral, Onitraz, Iycotizol, Itrasys, Syntran, Nixitral, I-Tyza, Afderm, Itraderm
Genxtor with Benidipine
SERIOUS
Medicines with composition Benidipine: Caritec
Genxtor with Lercanidipine
SERIOUS
Medicines with composition Lercanidipine: Lotensyl, Lervasc
Genxtor with Phenytoin
SERIOUS
Medicines with composition Phenytoin: Episol, Neptoin, C-Toin, Eptoin
Genxtor with Ketoconazole
SERIOUS
Medicines with composition Ketoconazole: Hyporal
Genxtor with Fosphenytoin
SERIOUS
Medicines with composition Fosphenytoin: Fosphen, Fosentin
Genxtor with Ritonavir
SERIOUS
Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax
Genxtor with Posaconazole
SERIOUS
Medicines with composition Posaconazole: Noxafil
Genxtor with Perindopril
SERIOUS
Medicines with composition Perindopril: Perihart
Genxtor with Indinavir
SERIOUS
Medicines with composition Indinavir: Indivan
Genxtor with Danazol
SERIOUS
Medicines with composition Danazol: Gonablok, Ladogal, Endometryl
Genxtor with Nimodipine
SERIOUS
Medicines with composition Nimodipine: Nimpod, Nimocer, Vasotop
Genxtor with Imidapril
SERIOUS
Medicines with composition Imidapril: Tanatril
Genxtor with S-Amlodipine
SERIOUS
Medicines with composition S-Amlodipine: S-Amcard, Esam, Big Dvr
Genxtor with Nifedipine
SERIOUS
Medicines with composition Nifedipine: Calnif, Depicor, Calbloc, Calcigard, Nicardia, Nepin, Nefidipine, Cardipin, Depin, Nifelat, Nifedine, Nifidip
Genxtor with Enalapril
SERIOUS
Medicines with composition Enalapril: Envas, Minipril, EL, Enapril, Hytrol, Bql, Normace, Canvas, Tenam, Nuril, Enace, Enam, Encardil, Myoace, Vasopril
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