Gemita 1000 mg/62.5 mg Injection

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Fresenius Kabi India Pvt Ltd

Composition for Gemita 1000 mg/62.5 mg Injection

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Primarily used for

Ovarian cancer, Acute renal failure, Head and neck cancer
Potentiallyunsafewith
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Lactation
DISCONTINUED
We do not sell this product at present

Medicine Overview of Gemita 1000 mg/62.5 mg Injection

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Side effects of Gemcitabine

Common

Nausea, Vomiting, Loss of appetite, Hair loss, Reduced blood platelets, Allergic reaction, Breathlessness, Decreased white blood cell count, Increased liver enzymes, Anemia, Influenza like symptoms, Blood in urine, Skin rash, Protein in urine.

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How to use Gemcitabine

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gemita 1000 mg/62.5 mg Injection works

Gemcitabine interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
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Uses of Mannitol

Mannitol is used in the treatment of acute renal failure, cerebral edema and glaucoma.
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Side effects of Mannitol

Common

Nausea, Vomiting, Headache, Dehydration.

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How to use Mannitol

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gemita 1000 mg/62.5 mg Injection works

Mannitol is an inert substance with high osmotic pressure. It draws water into the kidney, which in turn increases the amount of urine production. Mannitol is also used to lower the pressure inside the eye or swelling around the brain.

In Depth Information on Gemita 1000 mg/62.5 mg Injection

Expert advice for Gemcitabine

  • Not recommended in children or adolescents below 18 years of age.
  • Inform your doctor if you have history of heart problems, vascular problems or low production of blood cells from the bone marrow (myelosupression).
  • Inform your doctor if you have breathing problems or feel weak and pale as this could be a sign of kidney dysfunction; unexplained new or worsening dyspnea or evidence of severe pulmonary toxicity.
  • Take precautions if you are on a controlled sodium diet, as this medicine contains some amount of sodium.
  • You should undergo blood count, heart/kidney/liver function tests before therapy.
  • Do not take live or attenuated vaccines during therapy and avoid contact with persons who receive them.
  • Alcohol is an ingredient of this infusion. If you are suffering from alcoholism or epilepsy, you may have serious side effects. Other medication taken at this time may have altered effects. 
  • Women who are planning to become pregnant should be counselled about the toxic effect of this drug on babies. 
  • They should use two effective methods of contraception while on this therapy and 6 months after it.
  • Men who are going to use this therapy should not father a child while on this therapy and 6 months after it. They should also seek guidance and counselling on sperm conservation before taking this therapy.
  • Do not drive or use machinery after taking this drug as it may cause sleepiness which may worsen with alcohol use.

Expert advice for Mannitol

  • Tell your doctor if you have swelling, kidney problems, or heart problems (e.g., congestive heart failure).
  • Exercise caution in children <12 years and if you are an elderly patient.
  • Seek immediate medical attention if you have difficulty urinating or extreme dizziness.
  • You will be regularly monitored for lab tests such as blood electrolytes, kidney function, lung function, heart function and blood counts.
  • Do not drive or use any machinery after taking mannitol as it may cause dizziness.
  • Do not consume alcohol when on treatment with mannitol, as it may worsen its side effects.
  • Tell your doctor if you are planning or planning to become pregnant or are breastfeeding.
  • Do not take if allergic to mannitol or any of its ingredients.
  • Do not take in pre-existing plasma hyperosmolarity.
  • Do not take in severe dehydration, established anuria (failure of the kidneys to produce urine), severe heart failure, severe lung congestion or oedema, active intracranial bleeding (bleeding within the cranial vault), except during craniotomy (surgical removal of part of the bone from the skull to expose the brain).
  • Do not take if suffering from disturbance of the blood-brain barrier.
  • Do not take if suffering from progressive renal damage or dysfunction after institution of mannitol therapy, including increasing oliguria and azotemia (elevation of blood urea nitrogen).
Gemita Injection related warnings
Special precautions for Gemita Injection
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Gemita 1000 mg/62.5 mg Injection is unsafe to use during pregnancy.

There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
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Lactation
UNSAFE
Gemita 1000 mg/62.5 mg Injection is usafe to use during lact
ation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breast feeding is not advisable.
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Driving
Gemita 1000 mg/62.5 mg Injection may make you feel dizzy, sl
eepy, tired, or decrease alertness. If this happens, do not drive.
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Kidney
Gemita 1000 mg/62.5 mg Injection is probably safe to use in
patients with kidney disease. Limited data available suggests that dose adjustment of Gemita 1000 mg/62.5 mg Injection may not be needed in these patients. Please consult your doctor.
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Liver
There is limited information available on the use of Gemita
1000 mg/62.5 mg Injection in patients with liver disease. Please consult your doctor.
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Patient Concerns

Frequently asked questions about Gemita 1000 mg/62.5 mg Injection

Frequently asked questions about Gemcitabine

Q. Is Gemcitabine a vesicant/ anthracycline/ prodrug?
Gemcitabine is not a vesicant/ anthracycline/ prodrug
Q. Does Gemcitabine cause hair loss or abdominal pain?
Yes, Gemcitabine has hair loss and abdominal pain as side effects. Please consult your doctor immediately if you experience such side effects
Q. Is Gemcitabine a cytotoxic or chemotherapy agent?
Yes, Gemcitabine is a cytotoxic chemotherapy agent
Q. Does Gemcitabine work in pancreatic cancer?
Yes, Gemcitabine is used to treat pancreatic cancer.
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Frequently asked questions about Mannitol

Q. Is Mannitol a sugar?
Mannitol is a polyol (sugar alcohol)
Q. Is Mannitol salt agar selective?
Yes, Mannitol salt agar is a selective, differential and Indicator medium.

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