Fexostat 40mg Tablet

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Sanzyme Ltd

Composition for Fexostat 40mg Tablet

iconPrescription Required

Primarily used for

Potentiallyunsafewith
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Alcohol
75
₹7.5/Tablet
10 tablets in 1 strip
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Medicine Overview of Fexostat Tablet

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Uses of Fexostat Tablet

Fexostat 40mg Tablet is used in the treatment of gout.
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Side effects of Fexostat Tablet

Common

Increased liver enzymes, Diarrhoea, Headache, Nausea, Skin rash.

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How to use Fexostat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Fexostat 40mg Tablet at a fixed time.

How Fexostat Tablet works

Fexostat 40mg tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

In Depth Information on Fexostat Tablet

Expert advice for Fexostat Tablet

  • Your doctor has prescribed Fexostat to reduce episodes of gout attack.
  • Take Fexostat at the same time every day, with or without food.
  • Take plenty of fluids (2-3 litres) daily while on Fexostat.
  • Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Fexostat.
  • To ensure that Fexostat is working, you may have to undergo blood tests regularly.
  • When you first start taking Fexostat, you might have more gout attacks. Do not stop Fexostat on having an acute attack of gout as that could make an attack worse.
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Warnings
Special precautions for Fexostat 40mg Tablet
Alcohol
CAUTION
Taking alcohol can increase your uric acid levels and hence aggravate gout.
Pregnancy
WEIGH RISKS VS BENEFITS
Fexostat 40mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
CAUTION
Fexostat 40mg Tablet is probably usafe to use during lactati
on. Limited human data suggests that the drug could represent a significant risk to the baby.
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Driving
Do not drive unless you are feeling well.

Fexostat 40mg Tablet may cause dizziness, sleepiness, blurred vision, numbness or tingling sensation. This may affect your driving ability.
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Kidney
Fexostat 40mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Fexostat 40mg Tablet may be needed. Please consult your doctor.

Limited information is available regarding the use of Fexostat 40mg Tablet in these patients.
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Liver
Fexostat 40mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Fexostat 40mg Tablet may be needed. Please consult your doctor.

Limited information is available regarding the use of Fexostat 40mg Tablet in these patients.
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Missed Dosageuses

If you miss a dose of Febuxostat, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Patient Concerns

Frequently asked questions for Fexostat 40mg Tablet

Frequently asked questions for Febuxostat

Q. Can I take Fexostat with rosuvastatin?
Rosuvastatin can be taken with Fexostat. Rosuvastatin is used to lower bad cholesterol and Fexostat is used to lower uric acid levels in patients with gout. Many patients of high cholesterol levels also have high uric acid levels. There are no human studies available on this interaction. However, animal research shows that when given together, Fexostat can increase the blood levels of Rosuvastatin causing a higher risk of its side effects like muscle pain and muscle damage. So, a dose adjustment of Rosuvastatin may be needed when given along with Fexostat.
Fexostat is not known to cause frequent urination. However, if you experience any such symptom while using the drug, consult your doctor.
Gout is a type of arthritis in which uric acid levels are very high in the blood and they get deposited in the joints causing swelling, redness and sudden pain in these joints. Fexostat works by inhibiting the enzyme xanthine oxidase involved in the synthesis of uric acid and hence decreases the level of uric acid in the blood.
No, Fexostat is not a steroid. It is a xanthine oxidase inhibitor and decreases the serum uric acid levels.
Fexostat is not indicated for the treatment of hypertriglyceridemia. Conclusive evidence showing the drug lowering triglyceride levels is lacking.
After oral intake, the peak plasma concentration of Fexostat is achieved between 1 to 1.5 hours. However, it may take a few days to weeks to show its effect and you can experience gout attacks during this time. Continue to take your medicine during this time as with continuous use these attacks would decrease.
Q. How is Fexostat different from allopurinol?
Both allopurinol and Fexostat work in a similar way by lowering uric acid levels. However, as compared to allopurinol, Fexostat is seen to be more effective and faster in its action. Also, in patients taking allopurinol, a dose adjustment is needed if the patient has mild, moderate or severe renal failure while in the case of Fexostat a dose adjustment may be needed only in patients with severe renal failure.
Fexostat is not an over the counter product. It is a prescription medicine and is available as per the doctor's advice.
Studies have shown that Fexostat is safe for long-term use. However, it should be taken only for the duration as per the doctor's advice.
Fexostat is not indicated for the treatment of heart failure. However, high uric acid levels is a risk factor for cardiovascular diseases and the benefit of urate-lowering therapy for cardiac diseases is being explored.
Fexostat is not indicated for the treatment of chronic kidney disease. However, it can be safely used in patients with mild to moderate renal failure for lowering uric acid levels. Safety of the drug in severe renal failure is not established.
Fexostat is not used for the treatment of cancer. However, patients with malignant cancer when given anti-cancer drugs, experience a serious condition known as tumor lysis syndrome characterized by increased potassium, phosphate and uric acid levels in the blood due to the killing of cancer cells and this can lead to acute kidney injury, cardiac arrhythmia, and seizures. Fexostat helps in this condition by lowering the uric acid levels and preventing further complications.
Q. Can I take Fexostat with allopurinol?
Both Fexostat and allopurinol are uric acid lowering agents and work in a similar way. So, using both the two medicines together may not be very beneficial and can increase the risk of side effects. However, there have been studies where Fexostat when used with allopurinol in patients with refractory gout, was quite effective in providing relief. So, a combined use would be best decided by your treating doctor depending on your condition.
Fexostat is not indicated in the treatment of kidney stones. However, some studies show that high renal uric acid excretion may precipitate the formation of calcium stones in the kidney and hence, suggest Fexostat may have a role in the reduction of stone formation.
Q. Can I take Fexostat with colchicine?
Fexostat can be taken with colchicine. In the initial few days of starting Fexostat, patients may experience an increase in gout attacks because of the movement of uric acid and colchicine and painkillers are given to these patients for the relief of pain and inflammation.
Q. Can I take Fexostat with azathioprine?
Fexostat should not be taken with azathioprine. Taking both the medicines together will increase the levels of azathioprine and can cause toxicity.
Fexostat can generally be taken safely together with antibiotics. However, interactions can occur. Talk to your doctor about the right antibiotic therapy for your condition while you are also taking Fexostat.
Use of Fexostat is contraindicated in patients being treated with azathioprine, mercaptopurine, theophylline, and in patients who develop hypersensitivity to the drug.
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User Submitted Feedback For Fexostat 40mg Tablet

Survey Participants: 2
Disclaimer
“The following are the results of on-going survey on 1mg.com for Fexostat 40mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”
One of the following vendor pharmacies will deliver Fexostat 40mg Tablet: 9T9, KHH, OIP, ENP, PSP, ADT, RKS, MPC, DPP, JMJ, RSA, ATL, JIV, MAK, LHA, GTK, GNC, NDP, HIP, SHM, DYG, MOM, AAY, GPT, FGH, OWP, HEX, USF, BDN, HGI, HBV, SBL, AYU, NVL, SBA, WSI, DFP, BSN, RSS, EQN, ZVP, STA, AGT, PLT, DLP, SAF, LCC, SHP, SAT, OLT, BIO, PNT, MAX, EMB, SSA, GTC, OHM, RPP, SWA, IPL, DEL, RJH, NWP, BTM, SJP, BLP, ATP, RUS, RHW, AAR, PTS, PEN, DDR, MMS

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