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02 Apr 2020 | 10:13 AM (IST)
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Fastograf 300mcg Injection


Overview

Introduction

Fastograf 300mcg Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Fastograf 300mcg Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked for regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.

The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat and swelling around face or neck.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Fastograf Injection

  • Infections after chemotherapy

Side effects of Fastograf Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Fastograf

  • Bone pain
  • Weakness
  • Headache
  • Rash
  • Nausea
  • Increased lactate dehydrogenase level in blood
  • Vomiting
  • Increased uric acid level in blood
  • Oropharyngeal pain
  • Hair loss
  • Fatigue
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Cough
  • Breathing problems

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Bone pain
    Try to keep your joints moving. Get some gentle exercise like walking or cycling. Using hot and cold treatments on the joints can help reduce pain temporarily. Concentrate on your breathing when you are in pain. Try to get enough sleep. Practice some relaxation techniques or mediation. Avoid smoking as it can worsen your condition. Losing weight can make a big difference to the amount of pain. Ask your doctor to recommend some suitable painkillers if the pain bothers you or does not go away.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Hair loss
    Use gentle hair products such as baby shampoo. Use a soft brush and comb gently. Avoid using hairdryers, curling tongs or hair straighteners and pat your hair dry after washing. Do not color your hair. Protect your scalp by covering your head in the sun. It is necessary to not take the stress and eat a balanced, nutritious diet as it is vital for the health of your hair.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Decreased appetite
    It is important to eat, even if you do not feel like it. You might try switching to smaller meals and frequent snacks. Try eating healthy and nutritious snacks that are high in calories and protein, such as dried fruit and nuts. It is important to drink even if you cannot eat. But, do not fill your stomach with liquid before eating. Eat when you are most hungry. Exercise such as a short walk may also increase your appetite. Talk to your doctor about possible medication or supplements if your condition does not improve.
  • Coping with Cough
    Get plenty of rest as exhausting or stressing out yourself could aggravate your condition. You should drink plenty of fluids as it will keep your throat moist and comfortable. Try taking steam inhalation. The moisture can ease your breathing and loosen mucus. You can consider sipping warm water or tea with honey and lemon. This will keep your nose and throat from being too dry. Using an air humidifier may also help. You can also gargle with salt water several times a day. See your doctor if your symptoms last longer than 3 weeks or get worse quickly. Avoid alcohol and do not smoke as they can aggravate your conditions.
  • Coping with Breathing problems
    Control your breaths by breathing in slowly through your nose and breathing out through your mouth. Sitting on a chair and leaning your chest slightly forward may also help. Increase the flow of air around you by opening windows or using a fan. Try to learn breathing techniques and do regular physical exercise. Wearing loose clothing around your waist and chest may also be helpful. Your breathing will usually return to normal within a few weeks of starting the medicine. Tell your doctor if your symptoms do not improve or get worse. Shortness of breath can also be a sign of an ongoing or worsening heart problem.

How to use Fastograf Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Fastograf Injection works

Fastograf 300mcg Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Fastograf 300mcg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Fastograf 300mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Fastograf 300mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Fastograf 300mcg Injection may cause side effects which could affect your ability to drive.
Fastograf 300mcg Injection may cause fatigue. This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Fastograf 300mcg Injection is safe to use in patients with kidney disease. No dose adjustment of Fastograf 300mcg Injection is recommended.
Liver
SAFE IF PRESCRIBED
Fastograf 300mcg Injection is safe to use in patients with liver disease. No dose adjustment of Fastograf 300mcg Injection is recommended.

What if you forget to take Fastograf Injection?

If you miss a dose of Fastograf 300mcg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Fastograf 300mcg Injection
₹1442.33/ml of Injection
Grafeel Injection
Dr Reddy's Laboratories Ltd
₹1504.03/ml of Injection
4% costlier
Xphil 300mcg Injection
Sun Pharmaceutical Industries Ltd
₹2142.8/Injection
49% costlier
₹2443.68/Injection
69% costlier
₹2562.22/Injection
78% costlier
Emgrast 300mcg Injection
Emcure Pharmaceuticals Ltd
₹2800/ml of Injection
94% costlier

Quick Tips

  • Fastograf 300mcg Injection reduces the risk of infection in people treated with chemotherapy.
  • It is usually given as a daily injection into the tissue just under the skin or into the vein. 
  • You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
  • Store it in the refrigerator, protect it from light, and don't shake it.
  • For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
  • Use caution while driving or doing anything that requires concentration as Fastograf 300mcg Injection may cause dizziness.
  • Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
  • Stop taking Fastograf 300mcg Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Fact Box

Chemical Class
Granulocyte Colony-Stimulating Factor
Habit Forming
No

Patient Concerns

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Plz check the report and reply She is my wife report one of hospital where operated the tumot operation and one of from delhi srl and last one from tmh mumbai After the diagnosis docror advice rediation now 1 st rediation therapy is finished and doctor giving now nublast 250mg tab So plz check the report and tell me as per the tata memorial final report what is the condition for patient She can live normal life or she can dead in ahead Doctor tells with my family she can live with treatment more than 1 to 2 years Is it right or wrong
Dr. Vijay Sharnangat
Medical Oncology and Hematology
You are on right treatmentAfter completion of radiation therapy you need to take chemotherapyThat tablet is the chemotherapy
What is symptomatic after chemotherapy for metastatic spine
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Back pain is main symptom which you can get after disease progression
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User Feedback


FAQs

Q. Is Fastograf safe?

Fastograf is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. What is Fastograf/Fastograf neuopagen?

Neupogen is the brand name of Fastograf. Fastograf belongs to class of medication called as colony-stimulating factors

Q. How does it work?

They act by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections

Q. What are the uses of Fastograf?

Fastograf is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation

Q. Is Fastograf a steroid/antibiotic?

No, Fastograf belongs to class of medication called as colony-stimulating factors

Q. Is Fastograf FDA approved?

Yes, it has been approved by FDA for used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation

Q. Does Fastograf cause cancer?

No, Fastograf does not cause cancer

Q. Why does Fastograf cause bone pain?

The exact cause in unknown, but bone pain is a common side-effect of Fastograf.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1074-75.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 545-46.
  3. Filgrastim. North Harrow, Middlesex: Accord Healthcare Limited; 2014 [revised 06 Feb. 2019]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Filgrastim. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
A licensed vendor partner from your nearest location will deliver Fastograf 300mcg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP1442.33  Get 15% OFF
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₹1225.98
1 ml in 1 vial
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