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Evirenz 600mg Tablet


Overview

Introduction

Evirenz 600mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.

Evirenz 600mg Tablet reduces the chances of getting HIV-related complications and improves your lifespan. It can be taken empty stomach or with food and is prescribed in combination with other HIV medicines. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important to keep taking them regularly until your doctor tells you it is safe to stop.

Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or do not go away. Consult your doctor urgently if you experience a skin reaction or liver damage. 

Before taking it, tell your doctor if you have any skin, liver or kidney problems. While using it, you may need regular blood tests to check your blood cell counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Uses of Evirenz Tablet

Side effects of Evirenz Tablet

Common
  • Headache
  • Dizziness
  • Agranulocytosis (deficiency of granulocytes in the blood)
  • Insomnia (difficulty in sleeping)
  • Sleepiness
  • Vomiting
  • Allergic reaction
  • Nausea
  • Abnormal dreams
  • Fatigue
  • Increased liver enzymes
  • Anxiety
  • Fever
  • Itching
  • Difficulty in paying attention
  • Increased triglyceride level in blood
  • Rash

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Allergic reaction
    Avoid touching other areas of your body, especially your face. Wash the affected area with water. Put a cold compress such as an ice pack or wet washcloth on the itchy area in case of a mild reaction. Using moisturizing creams may also bring relief. Speak to your doctor if the itchiness or rash gets worse or does not go away. Get medical help right away if you see signs of severe allergic reactions such as difficulty breathing, swelling of face or throat, sudden weakness with dizziness and restlessness.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Abnormal dreams
    Try taking your medicine in the morning. If you have to take it more than once a day, speak to your doctor. To help yourself, try to go to bed and get up at the same time each day and reduce naps. Do some light exercise each day to tire yourself. Make sure the room is not too hot or too cold. Relax before bedtime by taking a bath or listening to music. Don't go to bed hungry. Try using earplugs. Meditation, deep breathing and relaxation exercises can also help. Talk to your doctor if you have tried these tips and they have not helped.
  • Coping with Increased liver enzymes
    There may be no symptoms, so your doctor should carry out a blood test and give you advice. Some lifestyle changes can bring down levels of liver enzymes. In general, you will need to stop drinking alcohol or limit the amount you drink, lose weight and keep active. Drink plenty of fluids to avoid dehydration. Eat a healthy diet. Some particular foods like nuts, fatty fish, coffee, tea, olive oil, sprouts and bananas may be beneficial. Try to control stress as this can make your symptoms worse.
  • Coping with Anxiety
    This often disappears when the condition you are being treated for is managed. You could ask your doctor about changing the dose of your medicine or alternatives if it is affecting your daily life or causing you distress. Psychological treatments may be available. Some things you can do to help yourself include stopping smoking, cutting down the amount of alcohol and caffeine you drink, and doing regular exercise. You should also eat a healthy diet and find out how to get sleep if you are having trouble. Try talking to a friend or family member. Calming breathing exercises and other relaxation techniques may also help.
  • Coping with Difficulty in paying attention
    If this medicine makes you feel this way, stop what you are doing and sit or lie down until you feel better. If the feeling does not go away or troubles you, do not take any more medicine and speak to a pharmacist or your doctor.
  • Coping with Increased triglyceride level in blood
    Talk to your doctor about this. You may need medicines to lower the amount of cholesterol and other fats in your blood. You can help yourself in a number of ways. Eat less fatty food, especially food that contains “saturated” fat. So, try to avoid fatty meat, butter, ghee, cheese, cakes and biscuits, and food containing coconut oil or palm oil. Eat more fruits and vegetables, brown rice and bread, nuts, seeds and oily fish. Exercise more. Try walking, swimming or cycling but find something you enjoy. Stop smoking and reduce the amount of alcohol you drink. Drink plenty of water and try to get a good night’s sleep.
  • Coping with Rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.

How to use Evirenz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Evirenz 600mg Tablet is to be taken empty stomach.

How Evirenz Tablet works

Evirenz 600mg Tablet prevents the multiplication of HIV virus in human cells, thereby stopping the HIV virus from producing new viruses.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Evirenz 600mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Evirenz 600mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Evirenz 600mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Evirenz 600mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Evirenz 600mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Evirenz 600mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Evirenz 600mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Evirenz 600mg Tablet may be needed. Please consult your doctor.
Use of Evirenz 600mg Tablet is not recommended in patients with moderate and severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Evirenz 600mg Tablet
₹74.42/Tablet
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Effahope 600mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹64.08/Tablet
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₹64.45/Tablet
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Efferven 600mg Tablet
Sun Pharmaceutical Industries Ltd
₹78.55/Tablet
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Efcure 600mg Tablet
Emcure Pharmaceuticals Ltd
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Quick Tips

  • Evirenz 600mg Tablet is used in combination with other medicines for the treatment of HIV (human immunodeficiency virus).
  • Take it on an empty stomach, preferably at bedtime to reduce side effects.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • Your doctor may check your liver function regularly. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • You might experience dizziness or abnormal dreams during initial days of treatment. Consult with a doctor if it bothers you or does not go away. 
  • Use a reliable method of contraception to prevent pregnancy while taking this medicine.

Interaction with Drugs

Taking Evirenz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Antep, C Lep, Ametol
LIFE-THREATENING
Brand(s): Femo, Fagene, Avifam
LIFE-THREATENING
Brand(s): Lafter, Lafudac, Lafty
LIFE-THREATENING
Brand(s): Acigo
LIFE-THREATENING

Patient Concerns

arrow
i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner
hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero
Dr. Atula Gupta
Dermatology
You still need to be on ART even if the viral load is undetectable
arrow
Do you have any questions related to Evirenz 600mg Tablet ?

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1643-644.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 861-62..
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 455-56.
  4. Efavirenz. Uxbridge, Middlesex: Bristol-Myers Squibb House; 1999 [revised 27 Feb. 2019]. [Accessed 31 Mar. 2019] (online) Available from:External Link
  5. Efavirenz. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2014 [revised 10 Dec. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  6. Medscape. EFavirenz. [Accessed 31 Mar. 2019] (online) Available from:External Link
  7. Efavirenz. Princeton, New Jersey: Bristol-Myers Squibb Company; 1998 [revised Sep. 2011]. [Accessed 31 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Best Price
₹1897.78
MRP2232.68  Get 15% OFF
30 tablets in 1 strip
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