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MD (Pharmacology), MBBS
Last updated:
27 Dec 2019 | 01:08 PM (IST)
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Epichlor 50mg Injection


Overview

Introduction

Epichlor 50mg Injection is used in the treatment of various types of cancers of blood, breast, stomach, lung, ovaries and soft tissues. It also helps to prevent the recurrence of bladder cancer after surgery.

It is given as a drip or infusion vein with extreme caution by a qualified medical professional. It can be used alone, or sometimes given together with certain other medicines as part of combination chemotherapy. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include nausea, low blood platelets, hair loss, absence of menstrual periods, fever and rash. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life threatening. Regular blood tests are required to monitor your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have liver disease, or have heart problem. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding.

Uses of Epichlor Injection

Side effects of Epichlor Injection

Common
  • Low blood platelets
  • Nausea
  • Hair loss
  • Absence of menstrual periods
  • Fever
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Weight loss
  • Decreased white blood cell count (neutrophils)
  • Hot flashes
  • Gastrointestinal inflammation
  • Rash
  • Low energy
  • Eye disorder

How to use Epichlor Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Epichlor Injection works

Epichlor 50mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the breast cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of breast cancer cells and eventually kills them.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Epichlor 50mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Epichlor 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Epichlor 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Epichlor 50mg Injection may cause side effects which could affect your ability to drive.
Epichlor 50mg Injection may cause episodes of nausea and vomiting, which can temporarily lead to an impairment of the ability to drive.
Kidney
SAFE IF PRESCRIBED
Epichlor 50mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epichlor 50mg Injection may not be needed in these patients. Please consult your doctor.
Lower doses may be considered in patients with serum creatinine > 5 mg/dL.
Liver
CAUTION
Epichlor 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Epichlor 50mg Injection may be needed. Please consult your doctor.
Use of Epichlor 50mg Injection is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Epichlor 50mg Injection
₹960.0/Injection
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Epicure 50mg Injection
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Epithra 50mg Injection
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₹971/Injection
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Erubin 50mg Injection
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Quick Tips

  • Epichlor 50mg Injection is used alone or in combination with other medicines for the treatment of various types of cancers.
  • It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
  • It may make you feel tired or sleepy.  Do not drive or do anything that requires mental focus until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
  • Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Patient Concerns

arrow
My child having JIA, i use Folitrax 50mg injection every week . How to recover
Vipul Aggarwal
Pl consult a rheumatologist for same
He has prostate cancer patient under gone surgery and biopsy report confirm it. He was taking lupride injection quarterly. but this injection is not available now. his PSA is now 14.3. .please suggest us.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Will forward you number, you will get it from himcall him for Injection
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Do you have any questions related to Epichlor 50mg Injection ?

FAQs

Q. Is Epichlor a vesicant (agent that causes tissue blistering and damage)?

Yes, Epichlor is a vesicant; it may cause tissue blistering if it leaks out of the vein

Q. Is Epichlor an anthracycline?

Yes, Epichlor belongs to anthracycline class of anti-cancer medicines

Q. Is Epichlor a doxorubicin?

Epichlor and doxorubicin are both anticancer agents that belong to the anthracycline group

Q. Is Epichlor an antibiotic?

Epichlor is an anticancer antibiotic

Q. What is Epichlor used for?

Epichlor is used in the treatment of various cancers including cancer of the breast, ovary, stomach, lung, bowel or rectum, malignant lymphomas (a type of blood cancer of infection-fighting cells of the blood) such as Hodgkin's disease and non-Hodgkin's lymphoma, leukemia (blood cancer), multiple myeloma (a type of blood cancer of infection-fighting cells of the blood). It may be used in bladder cancers and to prevent reoccurrence of bladder cancer after surgery

Q. What is Epichlor made from?

Epichlor is made from natural products produced by species of soil fungus Streptomyces

Q. How is Epichlor given?

Epichlor is given by injection into the vein or through a catheter into the bladder

Q. How effective is Epichlor?

Epichlor is effective in the treatment of various cancers including cancer of the breast, ovary, stomach, lung, bowel or rectum, malignant lymphomas (a type of blood cancer of infection-fighting cells of the blood) such as Hodgkin's disease and non-Hodgkin's lymphoma, leukemia (blood cancer), multiple myeloma (a type of blood cancer of infection-fighting cells of the blood). It may be used in bladder cancers and to prevent reoccurrence of bladder cancer after surgery. It effectively slows or stops the growth of cancer cells in the body

Q. How much does Epichlor cost?

The price of Epichlor may vary depending upon the brand prescribed to you. Please read the instruction on the package for the correct price of the product.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1715.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 478-79.
  4. Epirubicin hydrochloride. Wedel, Germany: Medac GmbH; 2008 [revised Jun. 2016]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
KHANDELWAL LABORATORIES PVT. LTD, 79/87 D.LADPATH, MUMBAI 400 033, INDIA
Best Price
₹768
MRP960  Get 20% OFF
1 Injection in 1 vial
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