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Endoxan Tablet

Zydus Cadila

Composition for Endoxan Tablet

Prescription Required

Primary uses of Endoxan Tablet

Potentiallyunsafewith
Lactation
MRP
39.97
₹4/Tablet
10 tablets in 1 strip
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Medicine Overview of Endoxan Tablet

Uses of Endoxan Tablet

Endoxan Tablet is used in the treatment of cancer and nephrotic syndrome.

Endoxan Tablet side effects

Common

Side Effects of Endoxan are Vomiting, Nausea, Hair loss, Fever, Blood in urine, Diarrhoea, Decreased white blood cell count (neutrophils).

How to use Endoxan Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endoxan Tablet is to be taken empty stomach.

How Endoxan Tablet works

Endoxan Tablet is an anti-cancer medication with immunosuppressive property. In cancer, it works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication.
In Depth Information on Endoxan Tablet

Expert advice for Endoxan Tablet

  • Monitor your blood counts with the help of regular blood tests while on treatment with cyclophosphamide.
  • Contact your doctor immediately if you experience difficulty in urinating, blood in urine or any other bladder/ kidney related problems while on treatment with cyclophosphamide.
  • Do not start treatment with cyclophosphamide if you are planning to receive any vaccine or if you have a surgery scheduled or you have had a surgical removal of the adrenal glands.
  • Take precautions as treatment with cyclophosphamide severely affects your immune system, increasing susceptibility to infections (e.g. pneumonia).
  • Caution must be exercised during use of cyclophosphamide in very ill patients, patients with kidney/liver disorders, lung problems and heart problems (related to QT prolongation and abnormal heartbeats).
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Endoxan Tablet related warnings

Special precautions for Endoxan Tablet
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Endoxan Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lactation
UNSAFE
Endoxan Tablet is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Driving
Do not drive unless you are feeling well.
Endoxan Tablet may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney
Endoxan Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Endoxan Tablet should be used with caution in patients with liver disease. Dose adjustment of Endoxan Tablet may be needed. Please consult your doctor.

Patient Concerns

Questions Related to Endoxan

MY mother suffered with RA Rehmatoid and IHD Dr. Prescribed methotrixate 10 mg and leflunomide my basic concern any side effect of this drugs, Like kidney disease, Cancer,
Dr. Akshat Goel
Bone & Joint Specialist
Every drug has some side effectstry to stop taking leflunomide after 2 months Also do KFT (kidney) test every 3 mo ths
Hello sir Sir I was suffering from cancer swing sarcoma in pelvis region s2 to s4 Sir the treatment was close and cured in26 Oct 2016 but due to radiation and chemotherapy my leg has been weak doctor say take advise to physio . I can walk properly but i can not run fast . So please suggest me what should I doDue to the radiation and chemotherapy I was suffering from impotency too
Dr. Mehtab Baig
Physiotherapist
Its ok don't worry, i suggests you only one way to keep easly you got muscke power,, sweeming and in water walk they're easy to improve your muscle strenght that is also known as aquatic therapy Serch or contact me
Can consuming Fenugreek And Flax Seeds Cause Breast and Overy Cancer i studed on net its cause Cancer. I take Flax seed power with Milk at Night 2 spoons and Fenugreek Seeds 1 spoon In water every morning empty stomach. Is It Safe For Me.Can consuming Fenugreek And Flax Seeds Cause Breast and Overy Cancer i studed on net its cause Cancer. I take Flax seed poweder with Milk at Night 2 spoons and Fenugreek Seeds 1 spoon In water every morning empty stomach. Is It Safe For Me.
Dr. Deepak Kumar Soni
Skin Specialist
these natural product people are using past so many years if you feel better after taking these Product you can use
I smoked cigarette for two years and then i quit. Never chewed tobacco. And i smoked at an average of 3 to 4 cigarette per day . Is my chances of getting smoking related cancer lowered now? I havent been smoking for a year now
Dr. Pushkar Mani
Diabetes Specialist
after 15- 20 yrs of smoking cessation chances are as low as to non smoker
I want ignore my tobacco habitDear sir Please suggest me what i doJust little fear in mind about cancer so that why i want to leave tobacco habit
Dr. Vijay Sharnangat
Cancer Specialist
Slowly avoid taking tobaccoTake help from deaddiction centre
I have been smoking for 8 years and now i want to quit smoking.give me some tips how to quit and what will happend after quitting smoking
Dr. Sajeela Maini
Quit Smoking
You will benefit tremendously when you quit smokings. every puff of cigarette contains 4800 chemical compunds and 68 carcinogens. it is wdely called a cancer stick.when you quit smoking your stamina will improve drastically, you will feel fresher and energetic whole day. We have a CO machine; we see the changes in the CO levels even after one day of quitting
I am doing gym from 4 months my aim of body is like tiger Shroff muscular body, perfect packabbs, trainer suggest me supliments like protien powder approx 5kg protien powder in 2 months, recommend me what should I do, my family history is father died due to cancer in lungs, gallbladder.
Dr. Pushkar Mani
Diabetes Specialist
never take food supplementsit can do harm never take any steroids for body buildinghigh protein can also damage ur kidney and other organsbetter take more natural sources , like eat 3-4 eggs, milk 1 litre, chiken , pulses in diet every day for protein

User Submitted Feedback For Endoxan Tablet

Survey Participants: 64
Disclaimer
“The following are the results of on-going survey on 1mg.com for Endoxan Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”

Frequently asked questions about Endoxan Tablet

Frequently asked questions about Cyclophosphamide
Q. Is Endoxan chemotherapy?
It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)
Q. Is Endoxan prodrug?
Yes. Endoxan is administered in the inactive form (prodrug) and gets converted to active form which has anti-cancer properties
Q. Does Endoxan have a boxed warning?
No. Endoxan does not have any specific boxed warning. Please discuss with your doctor about all the possible side effects and warnings relating to use of Endoxan
Q. Does Endoxan come in liquid form?
No. Endoxan comes in a dry powder form that be reconstituted to make a solution for injection or oral liquid as directed
Q. Is Endoxan a cytotoxic drug?
Yes. Endoxan is chemotherapy and a cytotoxic drug used in the treatment of various cancers
Q. Is Endoxan an antimetabolite/ steroid/ anthracycline?
No. Endoxan is an alkylating agent used in the treatment of various cancers. It is not an antimetabolite or anthracycline type of anti-cancer drug. It has a structure and effects different from steroids
Q. Is Endoxan a vesicant?
Endoxan is an irritant and can cause tissue inflammation at site of injection if its oozes out of the vein
Q. Does Endoxan cause hair loss/ infertility/ thrombocytopenia/ headaches/ hemorrhagic cystitis?
Yes. Hair loss (alopecia), infertility (in men and women), low platelet count (thrombocytopenia), headaches and inflammation of the urinary bladder (hemorrhagic cystitis) are among the known common side effects of Endoxan use
Q. Is Endoxan removed by plasma exchange?
Endoxan is unlikely to be removed by plasma exchange since a very low percentage of drug is bound to proteins in the plasma.

Severely interacts with other drugs like

Taking Endoxan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Endoxan with Polio Vaccine
SERIOUS
Medicines with composition Polio Vaccine: Biopolio B1/3
Endoxan with Clotrimazole
SERIOUS
Medicines with composition Clotrimazole: Clowil, Odis, Kamestin, Cano, Gynaemed, Clovag, Ctm V
Endoxan with Itraconazole
SERIOUS
Medicines with composition Itraconazole: Itraspan, Itzo, Canzit, Cositra, Belitra, Sitra, Ozitral, Itrapro, Icoz, Itrasil
SERIOUS
Medicines with composition Inactivated influenza vaccine: Ibivac, FluQuadri
Endoxan with Fluconazole
SERIOUS
Medicines with composition Fluconazole: Fungis, EF Z, Rocflu, Welcon, Fluzole, Geoflu, Rascon, Con F, Fucan, Flucur
Endoxan with Terbinafine
SERIOUS
Medicines with composition Terbinafine: Terbicutis, Terminator, Hifen, Anibret, Terbimet, Derbina, Mycosol, Tinacure, Terowin, Febitan
Endoxan with Digoxin
SERIOUS
Medicines with composition Digoxin: Cardisip
Endoxan with Voriconazole
SERIOUS
Medicines with composition Voriconazole: Voristil, Fungior
Endoxan with Miconazole
SERIOUS
Medicines with composition Miconazole: Canticid
Endoxan with Prasugrel
MODERATE
Medicines with composition Prasugrel: Prasunol, Prasuvas
One of the following vendor pharmacies will deliver Endoxan Tablet: RWL, SVS, RPA, MJT, QTM, EQN, GMA, DRA, 1MH, FRS, MOM, AYU, PSF, SBA, PLT, JHC, KAL, YAG, SPF, DYG, HMP, AGT, PHN, VHP, GHR, TAP, NXG, LIP, KHP, BRC, NXT, PPR, MAP, PMA, AVS, HBV, DLY, KIS, DPL, ANT, NVL, MRS, PNT, WHL, CLT, EMB, HTS, BGS, SDM, GBL, GTC, MKS, SLC, DZY, VDH, PSE, VOP, BAP, KNH, FIP, IPP, RSA, OWP, SPD, HIP, SWP, SPV, FGH, RWP, HSM, STA, PRN, JIV, TOM, GLM, EAN, RYL, SMS, ALC, UPA, ENP, BSL, SRG, IPL, GNC, KLC, DFP, WAD, USF, KMC, STS, WHP, NLP, PVP, OLT, SNH, RVC, SVH, RHS, BHA, BIO, AYN, NVY, CRN, NDP, NAS, SBN, NEW, MKT, SAA, HTV, BSN, MKE, PWN, DPP, SLN, AMH, NPS, HCP, AFT, SGH, MDO, BJP, TAT, RHL, BNA, CMD, CPK, LHA, BJR, MLC, NPH, HEX, 4IT, BNT, SBL, SNG, ATP, NFP, SGC, KIM, AHP, SDE, ASP, CMC, BKB, CZT, OHM, GPT, APS, AXM, BLP, AAY, VJS, WSI, UMP, MPC, INC, ANP, MDI, BBN, DVH, ANS, RGH, IAD, APT, NWP, MDH, RDR, MAX, DLP, SHD, ZPR, OBS, SAH, MAM, NTL, LHP, SHG, ALY, SSI, HNP, JJE, HWS, ESY, USM, JSL, AYM, BTM, MBP, WPL, BNC, BHM, PRC, NLC, AAR, GGL, GPP, KHH, RAC, DAO, BLE, JBT, KHD, BMJ, AVL, VRS, DHR, RPI, SCH, PRL, FRM, KHC, GLD, MTD, SIO, OIP, TSS, BAL, SSS, HLT, VSC, AVB, RHW, LMS, EVP, MSD, PEN, IMC, MFN, RDH, NTB, LCC, QLF, NNP, HSP, UHP, EPS, DHP, BDI, RST, RRP, SYN, VNS, SCP, SHN, VVN, RTL, PHC, AGP, MTM, AAA, GDA, GFL, SMN, SAF, THP, DYL, PTP, NSL, VTR, BHP, JVO, SHC, MDN, VSL, XMX, SWA, CTP, RPP, SJP, EEC, ZVP, BBS, ABP, SOF, AMR, PRT, HPP, NEO, NLG, ZEL, ADT, RKS, JVN, OMV, GEO, OWN, HGI, HZF, HAT, HPC, ARD, PTI, BLS, UVD, BHS, TNH, MIP, PNQ, AMM, ATL, 9MM, DGN, WDE

Substitutes for Endoxan Tablet

Cycloxan 50mg Tablet
Biochem Pharmaceutical Industries
₹3.86/Tablet
save 3%
Phosmid 50mg Tablet
Neon Laboratories Ltd
₹3.33/Tablet
save 17%
Cysmide 50mg Tablet
Samarth Life Sciences Pvt Ltd
₹3.5/Tablet
save 12%
Eldamide 50mg Tablet
Elder Pharmaceuticals Ltd
₹2.26/Tablet
save 43%
Cyclomet 50mg Tablet
BDH Industries Ltd
₹2.67/Tablet
save 33%
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