Medicine Overview of Endoxan Tablet
Endoxan 50 mg Tablet is used in the treatment of cancer
and nephrotic syndrome.
Side Effects of Endoxan are Vomiting, Nausea, Hair loss, Fever, Blood in urine, Diarrhoea, Decreased white blood cell count (neutrophils).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endoxan 50 mg Tablet is to be taken empty stomach.
Endoxan 50 mg Tablet is an anti-cancer medication with immunosuppressive property. In cancer, it works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication.
In Depth Information on Endoxan Tablet
- Monitor your blood counts with the help of regular blood tests while on treatment with cyclophosphamide.
- Contact your doctor immediately if you experience difficulty in urinating, blood in urine or any other bladder/ kidney related problems while on treatment with cyclophosphamide.
- Do not start treatment with cyclophosphamide if you are planning to receive any vaccine or if you have a surgery scheduled or you have had a surgical removal of the adrenal glands.
- Take precautions as treatment with cyclophosphamide severely affects your immune system, increasing susceptibility to infections (e.g. pneumonia).
- Caution must be exercised during use of cyclophosphamide in very ill patients, patients with kidney/liver disorders, lung problems and heart problems (related to QT prolongation and abnormal heartbeats).
Endoxan Tablet related warnings
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Endoxan 50 mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Endoxan 50 mg Tablet is unsafe to use during lactation.
Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Do not drive unless you are feeling well.
Endoxan 50 mg Tablet may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Endoxan 50 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan 50 mg Tablet may be needed. Please consult your doctor.
Endoxan 50 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Endoxan 50 mg Tablet may be needed. Please consult your doctor.
User Submitted Feedback For Endoxan 50 mg Tablet
Patients taking Endoxan 50 mg Tablet What were the side-effects while using Endoxan 50 mg Tablet? How do you take Endoxan Tablet? How much was the improvement? Please rate Endoxan 50 mg Tablet on price What are you using Endoxan Tablet for?
Non-small cell lung cancer
Survey Participants: 64
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Frequently asked questions about Endoxan Tablet
Q. Is Endoxan chemotherapy?
It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)
Yes. Endoxan is administered in the inactive form (prodrug) and gets converted to active form which has anti-cancer properties
Q. Does Endoxan have a boxed warning?
No. Endoxan does not have any specific boxed warning. Please discuss with your doctor about all the possible side effects and warnings relating to use of Endoxan
Q. Does Endoxan come in liquid form?
No. Endoxan comes in a dry powder form that be reconstituted to make a solution for injection or oral liquid as directed
Q. Is Endoxan a cytotoxic drug?
Yes. Endoxan is chemotherapy and a cytotoxic drug used in the treatment of various cancers
Q. Is Endoxan an antimetabolite/ steroid/ anthracycline?
No. Endoxan is an alkylating agent used in the treatment of various cancers. It is not an antimetabolite or anthracycline type of anti-cancer drug. It has a structure and effects different from steroids
Q. Is Endoxan a vesicant?
Endoxan is an irritant and can cause tissue inflammation at site of injection if its oozes out of the vein
Q. Does Endoxan cause hair loss/ infertility/ thrombocytopenia/ headaches/ hemorrhagic cystitis?
Yes. Hair loss (alopecia), infertility (in men and women), low platelet count (thrombocytopenia), headaches and inflammation of the urinary bladder (hemorrhagic cystitis) are among the known common side effects of Endoxan use
Q. Is Endoxan removed by plasma exchange?
Endoxan is unlikely to be removed by plasma exchange since a very low percentage of drug is bound to proteins in the plasma.
Severely interacts with other drugs like
Taking Endoxan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
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