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Endoxan 50 mg Tablet

Zydus Cadila

Composition for Endoxan 50 mg Tablet

Prescription Required

Primary uses of Endoxan 50 mg Tablet

Cancer, Nephrotic syndrome
Potentiallyunsafewith
Lactation
MRP
39.97
₹4/Tablet
10 tablets in 1 strip
ADD TO CART

Medicine Overview of Endoxan Tablet

Uses of Endoxan Tablet

Endoxan 50 mg Tablet is used in the treatment of cancer and nephrotic syndrome.

Endoxan Tablet side effects

Common

Side Effects of Endoxan are Vomiting, Nausea, Hair loss, Fever, Blood in urine, Diarrhoea, Decreased white blood cell count (neutrophils).

How to use Endoxan Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endoxan 50 mg Tablet is to be taken empty stomach.

How Endoxan Tablet works

Endoxan 50 mg Tablet is an anti-cancer medication with immunosuppressive property. In cancer, it works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication.

In Depth Information on Endoxan Tablet

Expert advice for Endoxan Tablet

  • Monitor your blood counts with the help of regular blood tests while on treatment with cyclophosphamide.
  • Contact your doctor immediately if you experience difficulty in urinating, blood in urine or any other bladder/ kidney related problems while on treatment with cyclophosphamide.
  • Do not start treatment with cyclophosphamide if you are planning to receive any vaccine or if you have a surgery scheduled or you have had a surgical removal of the adrenal glands.
  • Take precautions as treatment with cyclophosphamide severely affects your immune system, increasing susceptibility to infections (e.g. pneumonia).
  • Caution must be exercised during use of cyclophosphamide in very ill patients, patients with kidney/liver disorders, lung problems and heart problems (related to QT prolongation and abnormal heartbeats).
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Endoxan Tablet related warnings
Special precautions for Endoxan Tablet
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Endoxan 50 mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lactation
UNSAFE
Endoxan 50 mg Tablet is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Driving
Do not drive unless you are feeling well.
Endoxan 50 mg Tablet may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney
Endoxan 50 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan 50 mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Endoxan 50 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Endoxan 50 mg Tablet may be needed. Please consult your doctor.

Patient Concerns

User Submitted Feedback For Endoxan 50 mg Tablet

Survey Participants: 64
Disclaimer
“The following are the results of on-going survey on 1mg.com for Endoxan 50 mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”

Frequently asked questions about Endoxan Tablet

Frequently asked questions about Cyclophosphamide

Q. Is Endoxan chemotherapy?
It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)
Q. Is Endoxan prodrug?
Yes. Endoxan is administered in the inactive form (prodrug) and gets converted to active form which has anti-cancer properties
Q. Does Endoxan have a boxed warning?
No. Endoxan does not have any specific boxed warning. Please discuss with your doctor about all the possible side effects and warnings relating to use of Endoxan
Q. Does Endoxan come in liquid form?
No. Endoxan comes in a dry powder form that be reconstituted to make a solution for injection or oral liquid as directed
Q. Is Endoxan a cytotoxic drug?
Yes. Endoxan is chemotherapy and a cytotoxic drug used in the treatment of various cancers
Q. Is Endoxan an antimetabolite/ steroid/ anthracycline?
No. Endoxan is an alkylating agent used in the treatment of various cancers. It is not an antimetabolite or anthracycline type of anti-cancer drug. It has a structure and effects different from steroids
Q. Is Endoxan a vesicant?
Endoxan is an irritant and can cause tissue inflammation at site of injection if its oozes out of the vein
Q. Does Endoxan cause hair loss/ infertility/ thrombocytopenia/ headaches/ hemorrhagic cystitis?
Yes. Hair loss (alopecia), infertility (in men and women), low platelet count (thrombocytopenia), headaches and inflammation of the urinary bladder (hemorrhagic cystitis) are among the known common side effects of Endoxan use
Q. Is Endoxan removed by plasma exchange?
Endoxan is unlikely to be removed by plasma exchange since a very low percentage of drug is bound to proteins in the plasma.

Severely interacts with other drugs like

Taking Endoxan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
SERIOUS
Medicines with composition Cholera Vaccine (Inactivated): Shanchol
SERIOUS
Medicines with composition Rubella vaccine (Live): Rubella, R-VAC
Endoxan with Digoxin
SERIOUS
Medicines with composition Digoxin: Digon, Cardioxin, Sangoxin, Digitran, Digoxin
SERIOUS
Medicines with composition Inactivated influenza vaccine: Ibivac, Vaxigrip, Agrippal S1, Influenza, Nasovac-S, VaxiFlu-S, Influgen, Fluarix, Influvac, Lupienza, Zuviflu
Medicines with composition Bacillus Calmette-Guerin high strength: Oncovac, SII-Onco-BCG
Endoxan with Fluconazole
SERIOUS
Medicines with composition Fluconazole: Fungis, EF Z, Rocflu, Welcon, Fluzole, Geoflu, Rascon, Con F, Fucan, Flucur, Vanflu, Upcan, Flocoruth, Ifucan, Fluvate, Lucon, Biocan, Fungiker, AB Can, Flucot, Falkon, Fluocod, Orocan, Tycona, Forazen, E Fluke, Fluco, FN, Cantiz, Nix, Afuza, Flugen, F Cona, Candy, Alflu, Antol, Rutuflu, F One, Fungikil, Flozol, Fortab, Zocol, Flusys, Funcan, Udzole, Wyon, Wycon, Flutiz, Fungout, Recon, Source, Fluderm, Flutil, Flucona, Fusicon, Flum, Gynar, Conazol, Ocan, Docon, Flukel, Adi Flu, Cantin, Flustar, Antizole, Fluplas, HS, Flubar, Fitcan, Frezole, Flucimax, Flucom, Raulon, Stanflu, Von F, Funiz, Osofung, Topcan, Eselcon, B Con, Anti Fung, Fluza, Fuzol, Flurol, Flumarc, Fluzo, Nazole F, Vinfem, Fazol, Zomav, Efcan, AF, Nuflucon, Fungonil, Otoflu, Ntfung, Afflu, Flukem, Q Can, Fungicip, Stefazol, Faze, Nazole, Fluzol, Forcan Plus, Fungid Best, Flucan, Odcan, Canawar, Flusyst, Tricon, Fluri, V Can, Cozen, Zerocan, Sifcan, Nucon, Fole, Flucoric, Flutis, Flugee, Tucanozol, Vulcan, Fluzant, Flucess, Fludoc, Flucocid, Albican, Phozol, Triben F, Adifung, Futiza, Flutican, Ultican, Angloflu, Ozus, Endida, Flucovar, Nixican, Surfaz O, Fungibid, Fumycin, Fungina, Flustan, Myzole, Nipcan, Flucowin, Glenflu, Flucide, Fungiban, Manilin, Gocan, Jucan, Theozole, Fluzen, Staflu, Canzika, Flutec, Pracan, Candigyl, Fuspin, Fungipar, Locan, Lodogel, Fluent, Atcan, Alucon, Cazole, Lifecon, Nucan, Antif, Fluson, Fungikem O, Fludon, Fonazole, Trican, Aglocon, Fluoc, Utican, Flucole, Kozole, Zefun, Acroflu, Flair, Fludar, Fluzon, FZ, Flunaz, Scasis, Solcan, Fconaz, Flutrox, Syfun, Funaz, Zolcan, Zocon Inf, Antican O, Lodo, Adcon, Clozole V6, Flucopride, Logican, Zolen, F Con, Flucol P, Flumed, Flucofit, Fluconorm, Zecon, Fcn, Depxit, Nuconazole, Fungicon, Flucaz, Floret, Trucand, Fluxan, Freek, Flucalup, Flustate, Fusys, Fungid, Fluxit, Fluzide, Markzole, Sancan, Fungisanf, Saf F, Venzol, Fluact, Uco, Odicon, Flucomet, Fluka, Floroxan, Flu Z, Fluna, Flunac, Fluconex, Fluneon, Mcstat, Fungi, Flucolab, Freecan, Vilzole, Adecon, Falcon, Fedil, Flunova, Neocan, Fzhh, Hinzole, Fungo, Fluconij, Flumit, Con, Mycosure, Flz, Sysflu, Fungal F, Monila F, Hilzol, Intawin, Flucobig, Flucina, Fluher, Fungiset, Force, Fczol, Flu
SERIOUS
Medicines with composition Rabies vaccine, Human: Worab, Rabipur, Rabies, Verorab Antirabies, Indirab, Zoonovac, Vaxirab, Xprab
Endoxan with Sertaconazole
SERIOUS
Medicines with composition Sertaconazole: Sertazol V
Medicines with composition Inactivated Hepatitis A Vaccine (Adsorbed): Avaxim, Havrix, HAVpur Junior
Endoxan with Polio Vaccine
SERIOUS
Medicines with composition Polio Vaccine: Biopolio B1/3, Oral Polio, Polio Vvm, Opv
SERIOUS
Medicines with composition Human Rabies Immunoglobulin: Berirab P, Kamrab
SERIOUS
Medicines with composition Measles Vaccine (Live): Abhay M, Measles
Endoxan with Voriconazole
SERIOUS
Medicines with composition Voriconazole: Voristil, Vhope, Vorifit, Vorzu, Vonfung Ndd, Vorineon, Vorimed
Medicines with composition Varicella Vaccine (live) attenuated: Biovac V, Varivaxo, Okavax Std, Varivax, Variped, Zostavax
Medicines with composition Inactivated Japanese Encephalitis virus protein: Jeev, Jenvac
SERIOUS
Medicines with composition Equine Rabies Immunoglobulin: Equirab, Carig, Zyrig, AbhayRIG
Endoxan with Posaconazole
SERIOUS
Medicines with composition Posaconazole: Noxafil
Medicines with composition Rotavirus vaccine (live attenuated,oral): Rotarix, RotaTeq, Rotavac, Rotasure
Endoxan with Fenticonazole
SERIOUS
Medicines with composition Fenticonazole: Fenza
Medicines with composition Yellow fever virus (live, attenuated): Stamaril
SERIOUS
Medicines with composition Bacillus Calmette-Guerin: Tubervac
One of the following vendor pharmacies will deliver Endoxan 50mg Tablet: MPC, SDM, BHM, IMC, RPP, TRP, PTP, NDP, CRN, PRL, 9MM, IPL, SRG, BIO, AVS, OBS, QTM, BHA, BDI, NTB, LMS, DHR, HAT, BBN, SVH, SSI, XMX, STS, ENP, BNA, NVY, RGH, RKS, TFP, SJP, BAL, DVH, CPK, NNP, AVB, SCH, KHD, HBV, UVD, MAP, SVS, AYN, GBL, BLE, SNG, SCP, RWP, VSL, THP, TAT, OWP, MLC, ABP, MSD, SLN, GHR, HMP, WHL, DLP, MMS, EAN, GMA, SAF, NNH, GPP, SBA, HLT, ZPR, HTS, UHP, APS, VTR, DPP, DRA, AFT, JHC, SNH, RUS, DYG, RSS, AMH, HNP, FRM, ATP, PRN, GLD, BDN, PRT, HZF, AVL, BSN, SHD, YMI, ZEL, VHP, 1MH, ASP, SGH, BLS, LCC, NTL, CHP, MDO, VDH, NVL, GNC, BRC, INC, KLC, PRC, KHC, SWP, NXG, MKS, DAO, JSL, STA, RHL, DFP, CLT, BGS, CMC, KIS, SGC, ARD, KHH, JJE, BTM, PTI, NSL, BJP, JVO, NAS, LHA, SWA, VSC, AGT, AAY, WPL, DPL, JIV, MDH, RAC, EEC, ADT, BAP, IAD, WAD, BHP, AXM, AYM, EPS, RDH, BBS, SSA, BMJ, AYU, HGI, RPI, PWN, TNH, BNT, GLM, SYN, PHN, HSM, MBP, SMS, HPP, GPT, HIP, TSS, RSA, PLT, AMR, SDE, VNS, ALC, MAK, KNH, VJS, MKT, AAR, DZY, AWS, MAM, HCP, PHC, GDA, ATL, BLP, ANT, GTK, UMP, USF, HEX, ESY, JBT, OHM, SMN, PPR, RDR, RHW, PNT, OIP, SWT, ZVP, 4IT, OLT, HPC, TOM, DHP, EQN, MAX, GEO, SHC, VRS, DGN, NEO, QLF, VOP, SPD, EMB, HSP, SBL, PVP, WSI, FGH, BHS, JVN, LHP, ANP, PMA, DYL, GTC, KMC

Substitutes for Endoxan Tablet

Cycloxan 50mg Tablet
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save 3%
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Cysmide 50mg Tablet
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