Endoxan 1gm Injection

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Zydus Cadila

Composition for Endoxan 1gm Injection

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Potentiallyunsafewith
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Lactation
174.41
₹8.72/Injection
20 ml in 1 vial
SOLD OUT

Medicine Overview of Endoxan Injection

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Uses of Endoxan Injection

Endoxan 1gm Injection is used in the treatment of blood cancer, breast cancer, non-small cell lung cancer and ovarian cancer.
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Side effects of Endoxan Injection

Common

Fever, Blood in urine, Hair loss, Urinary tract infection, Mucosal inflammation, Decreased white blood cell count (neutrophils), Infection, Bone-marrow suppression.

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How to use Endoxan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Endoxan Injection works

Endoxan 1gm injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

In Depth Information on Endoxan Injection

Expert advice for Endoxan Injection

  • Monitor your blood counts with the help of regular blood tests while on treatment with cyclophosphamide.
  • Contact your doctor immediately if you experience difficulty in urinating, blood in urine or any other bladder/ kidney related problems while on treatment with cyclophosphamide.
  • Do not start treatment with cyclophosphamide if you are planning to receive any vaccine or if you have a surgery scheduled or you have had a surgical removal of the adrenal glands.
  • Take precautions as treatment with cyclophosphamide severely affects your immune system, increasing susceptibility to infections (e.g. pneumonia).
  • Caution must be exercised during use of cyclophosphamide in very ill patients, patients with kidney/liver disorders, lung problems and heart problems (related to QT prolongation and abnormal heartbeats).
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Warnings
Special precautions for Endoxan 1gm Injection
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Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
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Pregnancy
WEIGH RISKS VS BENEFITS
Endoxan 1gm Injection is unsafe to use during pregnancy.

There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
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Lactation
UNSAFE
Endoxan 1gm Injection is usafe to use during lactation. Dat
a suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breast feeding is not advisable.
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Driving
Do not drive unless you are feeling well.

Endoxan 1gm Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
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Kidney
Endoxan 1gm Injection should be used with caution in patient
s with severe kidney disease. Dose adjustment of Endoxan 1gm Injection may be needed. Please consult your doctor.
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Liver
CAUTION
Endoxan 1gm Injection should be used with caution in patient
s with liver disease. Dose adjustment of Endoxan 1gm Injection may be needed. Please consult your doctor.
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Severely interacts with other drugs like
Onitraz 100mg Capsule, Flugee 150mg Tablet, Canditz 100mg Capsule, Fixtral 100mg Capsule

Patient Concerns

Frequently asked questions for Endoxan 1gm Injection

Frequently asked questions for Cyclophosphamide

It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)
Yes. Endoxan is administered in the inactive form (prodrug) and gets converted to active form which has anti-cancer properties
No. Endoxan does not have any specific boxed warning. Please discuss with your doctor about all the possible side effects and warnings relating to use of Endoxan
No. Endoxan comes in a dry powder form that be reconstituted to make a solution for injection or oral liquid as directed
Yes. Endoxan is chemotherapy and a cytotoxic drug used in the treatment of various cancers
No. Endoxan is an alkylating agent used in the treatment of various cancers. It is not an antimetabolite or anthracycline type of anti-cancer drug. It has a structure and effects different from steroids
Endoxan is an irritant and can cause tissue inflammation at site of injection if its oozes out of the vein
Yes. Hair loss (alopecia), infertility (in men and women), low platelet count (thrombocytopenia), headaches and inflammation of the urinary bladder (hemorrhagic cystitis) are among the known common side effects of Endoxan use
Endoxan is unlikely to be removed by plasma exchange since a very low percentage of drug is bound to proteins in the plasma.
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Substitutes for Endoxan Injection

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