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MRP: Rs. 499 for 1 strip(s) (10 capsules each)
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Composition for ENDOSIS

Dienogest(2 mg)

food interaction for ENDOSIS

alcohol interaction for ENDOSIS

pregnancy interaction for ENDOSIS

lactation interaction for ENDOSIS

It can be taken with or without food, but it is better to take Endosis 2 mg capsule at a fixed time.
Taking Dienogest with alcohol can cause minor side effects
Endosis 2 mg capsule is highly unsafe in women who are or may become pregnant.
Human and animal studies have shown significant adverse effects on the fetus and should not be given under any circumstances. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Dienogest(2 mg)


Endosis 2 mg capsule is used as an oral contraceptives to prevent pregnancy and to treat heavy menstrual bleeding (not caused by any disease of the womb) in women who wish to use oral contraception.

How it works

Endosis 2 mg capsule belongs to a class of drugs called as progestogens. It may be used as a contraceptive alone or in combination with estrogens (in combined oral contraceptive pills). It suppresses ovulation (a process in which a mature egg is released from the ovary) and also thickens secretions from the cervix and vagina inhibiting sperm penetration and alters the lining of the uterus thereby reducing the possibility of the fetus implantation.

Common side effects

Abdominal pain, Acne, Breast discomfort, Deep vein thrombosis, Pain during periods, Headache, Irregular menstrual cycle, Absence of menstrual periods, Weight gain


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Expert advice for ENDOSIS

• Inform your doctor if you or close relatives of yours have the propensity to form blood clots, e.g clots in blood vessels of leg, lungs, or have experienced heart attack, stroke, or suffer from compromised blood supply to any part of the body, especially hands and legs.
• Tell your doctor if your close relative has or has had breast cancer.
• Seek immediate medical attention if you notice possible signs of a blood clot such as a blood clot in the leg (pain, swelling, redness, discoloration of the leg), a blood clot in the lung (pulmonary embolism; breathlessness, wheezing, irregular heartbeats, cough, dizziness etc.), a heart attack or a stroke. 
•Tell your doctor if you have a disease that first appeared during pregnancy or earlier use of sex hormones, such as  hearing loss, porphyria (a disease of the blood), gestational herpes (skin rash with blisters during pregnancy) or Sydenham’s chorea (a nerve disease causing sudden, uncontrolled movements of the body).
• Seek immediate medical attention if you experience symptoms of angioedema/allergy such as swollen face, tongue and/or throat and/or difficulty swallowing or itchy rash, together with difficulty breathing. 
• Tell your doctor if you are pregnant or breastfeeding or if you have just given birth. 
• Patients allergic to dienogest or any of its ingredients should not be given dinigest.
• Women with presence or risk of venous thromboembolism (blood clots in blood vessels of the leg or lungs) should avoid it.
• Women undergone any major surgery with prolonged immobilization should avoid dienogest intake.
• Women with presence or risk of arterial thromboembolism (blood clots in arteries, causing compromised blood supply to heart, brain, hands, and legs) should avoid it.

Frequently asked questions for ENDOSIS


Q. Is dienogest antiandrogenic?
Dienogest has an antiandrogenic activity and mainly act by blocking the action of testosterone.
Q. Is dienogest as effective as leuprolide or triptorelin?
Apart from its indication as oral contraceptive, dienogest is also indicated for endometriosis (a condition resulting from the appearance of endometrial tissue outside the womb and causing pelvic pain, especially associated with menstruation). Dienogest is as effective as leuprolide and triptorelin in the treatment of endometriosis. 


Content on this page was last updated on 24 June, 2015, by Dr. Varun Gupta (MD Pharmacology)