1mg, best e pharmacy in India


MRP: Rs. 160 for 1 strip(s) (10 capsules each)
Unfortunately, we don't have any more items in stock
Report Error

Composition for EFEM

Evening Primrose Oil(500mg),Tocoferol(30mg)

food interaction for EFEM

alcohol interaction for EFEM

pregnancy interaction for EFEM

lactation interaction for EFEM

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Efem 500mg/30mg capsule may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Evening Primrose Oil(500mg)


Used for treating rheumatoid arthritis and diabetic neuropathy, eczema, psoriasis, acne, , cancer, high cholesterol, heart disease, a movement disorder in children called dyspraxia, leg pain due to blocked blood vessels (intermittent claudication), alcoholism, alzheimer's disease, and schizophrenia.

How it works

The GLA provided by evening primrose oil can be converted directly to the prostaglandin precursor di-homo-gamma-linolenic acid and might be beneficial to individuals unable to metabolize cis -linoleic acid to GLA or those with low dietary intake of cis -linoleic acid.

Common side effects

Diarrhoea, Headache, Nausea, Stomach upset


In vitamin E deficiency due to digestive malabsorption in paediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis, from birth (full term newborns) up to 18 years of age.

How it works

Vitamin E's anti-atherogenic activity involves the inhibition of the oxidation of LDL and the accumulation of oxLDL in the arterial wall. It also appears to reduce oxLDL-induced apoptosis in human endothelial cells. Vitamin E inhibits protein kinase C (PKC) activity. The inhibition of PKC results in inhibition of smooth muscle cell proliferation, which is involved in atherogenesis.Vitamin E's antithrombotic and anticoagulant activities involves the downregulation of the expression of intracellular cell adhesion molecule(ICAM)-1 and vascular cell adhesion molecule(VCAM)-1 which lowers the adhesion of blood components to the endothelium. Vitamin E upregulates the expression of cytosolic phospholipase A2 and cyclooxygenase (COX)-1 which in turn enhances the release of prostacyclin. Prostacyclin is a vasodilating factor and inhibitor of platelet aggregation and platelet release. Vitamin E has also been found in culture to decrease plasma production of thrombin, a protein which binds to platelets and induces aggregation. A metabolite of vitamin E called vitamin E quinone or alpha-tocopheryl quinone (TQ) is a potent anticoagulant. This metabolite inhibits vitamin K-dependent carboxylase, which is a major enzyme in the coagulation cascade. Many disorders of the nervous system are caused by oxidative stress. Vitamin E protects against this stress, thereby protecting the nervouse system.

Common side effects

Necrotizing enterocolitis, Bleeding due to vitamin k deficiency, Blurred vision, Diarrhoea, Fatigue, Flatulence, Headache, Increased creatinine level in blood, Stroke


No substitutes found


Content on this page was last updated on 12 April, 2015, by Dr. Varun Gupta (MD Pharmacology)