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MD Pharmacology, MBBS
Last updated
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Duojet 1.25mg/500mcg Respules (2.5 ml Each)


Product introduction

Duojet 1.25mg/500mcg Respules (2.5 ml Each) is used for the treatment of chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It helps in relaxing the muscles of the air passages and making it easier to breathe. It relieves coughing, wheezing and feeling short of breath.

Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your COPD may get worse. This medicine should not be used to relieve sudden shortness of breath. If sudden shortness of breath occurs, use your rescue inhaler. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.

The most common side effects are dryness in mouth, shortness of breath, cough, tremor, headache, palpitations, and muscle cramp. If you get there, don’t stop taking it but do talk to your doctor. You can prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.


Uses of Duojet Respules

Benefits of Duojet Respules

In Treatment of Chronic obstructive pulmonary disease (COPD)

Duojet 1.25mg/500mcg Respules (2.5 ml Each) is a combination of medicines that helps the airways in your lungs stay open. They work by relaxing the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily.
Duojet 1.25mg/500mcg Respules (2.5 ml Each) is a safe and effective medicine. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor. You need to use your inhaler correctly for it to work properly. If you are not sure, ask your doctor or nurse.

In Treatment and prevention of Asthma

Asthma is a disease of the lungs that makes breathing difficult. It is caused by swelling of the airways that carry air in and out of the lungs. Duojet 1.25mg/500mcg Respules (2.5 ml Each) reduces swelling of the airways and widens it. This makes it easier for air to move in and out of the lungs.

In Treatment and prevention of Bronchitis

Duojet 1.25mg/500mcg Respules (2.5 ml Each) relieve sudden constriction of the muscles in the walls of the airway and enhance the airflow. This reduces mucous production, and promote easier breathing. This way it helps in managing the symptoms of bronchitis and improving respiratory function, contributing to an improved overall well-being for individuals with this condition.

Side effects of Duojet Respules

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duojet

  • Dryness in mouth
  • Cough
  • Tremors
  • Headache
  • Palpitations
  • Muscle cramp
  • Back pain
  • Chest pain
  • Fatigue
  • Dizziness
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Constipation
  • Taste change
  • Sore throat

How to use Duojet Respules

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.

How Duojet Respules works

Duojet 1.25mg/500mcg Respules (2.5 ml Each) is a combination of two medicines: Levosalbutamol and Ipratropium. Levosalbutamol is a bronchodilator while Ipratropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.

Safety advice

Alcohol
UNSAFE
Duojet 1.25mg/500mcg Respules (2.5 ml Each) may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Duojet 1.25mg/500mcg Respules (2.5 ml Each) may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Duojet 1.25mg/500mcg Respules (2.5 ml Each) is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Duojet Respules?

If you miss a dose of Duojet 1.25mg/500mcg Respules (2.5 ml Each), use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Duojet 1.25mg/500mcg Respules (2.5 ml Each)
₹13.5/Respules
₹124.7/respules
774% costlier
Nebzmart IL Smartules
Glenmark Pharmaceuticals Ltd
₹133.2/respules
834% costlier
Iprazest Respules (3ml Each)
Macleods Pharmaceuticals Pvt Ltd
₹110/respules
671% costlier
₹120/respules
742% costlier
Binafide Duo Respules
Torrent Pharmaceuticals Ltd
₹43.95/respules
208% costlier

Quick tips

  • Duojet 1.25mg/500mcg Respules (2.5 ml Each) is a combination of two medicines that makes breathing easier for patients with chronic obstructive pulmonary disease (COPD).
  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. 
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
  • Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Duojet 1.25mg/500mcg Respules (2.5 ml Each) can lower blood potassium level.
  • Only miniscule amounts of Duojet 1.25mg/500mcg Respules (2.5 ml Each) may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Fact Box

Habit Forming
No
Therapeutic Class
RESPIRATORY

Patient concerns

arrow
My mother is suffering from acute asthma And she has chronic bronchitis
Dr. Saurav Arora
Homeopathy
As your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly.
Old cough at morning last 15 years
Dr. Vijay Verma
ENT
can be bronchial asthma or COPD consult chest physician
arrow

User feedback


FAQs

Q. Are there any medicines which I should avoid while taking Duojet 1.25mg/500mcg Respules (2.5 ml Each)?

It is not recommended to use Duojet 1.25mg/500mcg Respules (2.5 ml Each) along with other medicines, such as anticholinergic, beta-adrenergic agents, beta-blockers, diuretics, digoxin, MAO inhibitors or anti-depressants.

Q. Will Duojet 1.25mg/500mcg Respules (2.5 ml Each) be more effective if taken in higher doses?

No, taking a higher than the recommended dose of this medicine will not make it more effective, rather can lead to increased side effects. If the symptoms do not get relieved by the recommended doses, please consult the doctor for re-evaluation.

Q. Can the use of Duojet 1.25mg/500mcg Respules (2.5 ml Each) cause sleepiness or drowsiness?

Yes, Duojet 1.25mg/500mcg Respules (2.5 ml Each) may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Q. Can the use of Duojet 1.25mg/500mcg Respules (2.5 ml Each) cause dry mouth?

Yes, the use of Duojet 1.25mg/500mcg Respules (2.5 ml Each) can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night.

Q. What are the instructions for storage and disposal of Duojet 1.25mg/500mcg Respules (2.5 ml Each)?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Levalbuterol. Marlborough, MA: Sunovion Pharmaceuticals Inc; 1999. [Accessed 17 Apr. 2019] (online) Available from:External Link
  2. Ipratropium. Bracknell Berkshire: Boehringer Ingelheim Limited; 2004 [revised Feb. 2018]. [Accessed 01 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Levalbuterol. [Accessed 17 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Ipratropium. [Accessed 17 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Brinton Pharmaceuticals Pvt Ltd
Address: Brinton Pharmaceuticals Ltd., Brinton House, Survey No. 55/2, Kharadi, Pune - 411014, India.
Country of origin: India

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