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Advanced International Certification Course in Diabetes, Cardio-diabetes, Thyroid and Endocrine Disorders, BDS
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Last updated on:
24 Jan 2019 | 06:30 PM (IST)
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Duloxit 30 mg Tablet EC

Prescription Required

Overview

Uses of Duloxit Tablet EC

Duloxit 30 mg Tablet EC is used in the treatment of depression, anxiety disorder, diabetic nerve pain, fibromyalgia, neuropathic pain and stress urinary incontinence.

Duloxit Tablet EC side effects

Common
  • Nausea
  • Headache
  • Dryness in mouth
  • Sleepiness
  • Dizziness

How to use Duloxit Tablet EC

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duloxit 30 mg Tablet EC may be taken with or without food, but it is better to take it at a fixed time.

How Duloxit Tablet EC works

Duloxit 30 mg Tablet EC works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.

Duloxit Tablet EC related warnings

Alcohol
CAUTION
Duloxit 30 mg Tablet EC may cause excessive drowsiness with alcohol.
Pregnancy
WEIGH RISKS VS BENEFITS
Duloxit 30 mg Tablet EC may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Duloxit 30 mg Tablet EC is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
Duloxit 30 mg Tablet EC may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Kidney
Duloxit 30 mg Tablet EC should be used with caution in patients with severe kidney disease. Dose adjustment of Duloxit 30 mg Tablet EC may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild and moderate kidney disease.
Liver
UNSAFE
Duloxit 30 mg Tablet EC is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you miss a dose of Duloxit Tablet EC?

If you miss a dose of Duloxit 30 mg Tablet EC, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • Duloxit 30 mg Tablet EC helps in treating depression and anxiety.
  • It may also  be used to treat nerve pain from diabetes and some other forms of chronic pain.
  • It may take 2 to 4 weeks for Duloxit 30 mg Tablet EC to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Duloxit 30 mg Tablet EC as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause an increase in blood pressure, especially during the first month of treatment. Monitor your blood pressure regularly.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Duloxit with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Kopram, Ecit, Escnx
SERIOUS
Brand(s): Attera
SERIOUS
Brand(s): Zosert, Sernit
SERIOUS
Brand(s): Psycolith
SERIOUS
Brand(s): Leparox, Prx, Paromec
SERIOUS
Brand(s): Flotin, Serodep, Fluxen
SERIOUS

Patient Concerns

Questions Related to Duloxit

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I am prescribed Lonazep MD 0.5mg twice a day for anxiety. Its causing me depression. Is there any other GABA medication that is not addictive and does not results in depression?
Dr. Ambrish Dharmadhikari
Mental Wellness
Benzodiazepines are usually do not cause depressionSerotonin and norepinephrine reuptake inhibitors are commonly used in anxiety disorderAs well as depression
Hi my name is PATIENT i was always a weak kid in school growing up my parents got seperated,leading my mother basically abandoning me after grade 5.I could never concentrate in school and i always wanted to be outdoors and my marks were terrible ! but anyway in the up-coming years i shifted a lot of shcools had a lot of failures and identety crises could never really calm down and figure what the problem is at the age of 20 i started working at an IT company which was really hard for me to get into but basically a job that i loved ! i was good at it too then i got sacked because i wasn't being able to concentrate again and i started losing interest.Well coming to the point i started seeing my first psycatrist in a year ago and he said i just had genralized anxiety disorder which i was given medication for but didn't solve my depression at all then i went to someone i was diagnosed with add but my main problem as if now is that i was on dazzle 20-30 mg for 15 days and it made me feel too drowzy and slow and blocked my thoughts now my doctor has percribed pregawave-m,S methiwave-400 and vilamid-20 but i haven't had them because I'm scared of the side effects my questions are :- 1. Can i consume alcahol with this drug combination ? 2. is there something more lighter ? 3.is ayurveda better ? 4.and does clinical depression wave off and how long do i take the meds ?
Dr. Jyoti Kapoor Madan
Psychiatrist
1. It is not advisable to take alcohol with medicines. 2. There is no heavy or light medicines. It's individual body's pharmacokinetic response. What suits one may not suit another. If you are having side effects, your psychiatrist can modify regimen accordingly. 3. A qualified Ayurvedacharya will know if he/ she can treat your condition. There are no comparative research studies between Ayurvedic and allopathic regimens to conclude if one is better than the other but as an Allopathy practitioner, I find satisfactory response with psychotropics. 4. Depression and anxiety are neurochemical responses to emetic and environmental factors. Treatment includes both medicines and psychotherapy for developing positive coping skills. Duration and response depend on a number of factors like history, symptom severity, duration and individual personality. Only time will tell if one is completely cured with or without medicines.
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FAQs

Q. Is Duloxit a non-steroidal anti-inflammatory drug (NSAID)?

No. Duloxit is not a non-steroidal anti-inflammatory drug (NSAID). It belongs to the anti-depressant class of drugs, more specifically SNRI (Serotonin-Norepinephrine Reuptake Inhibitor). It works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the nervous system.

Q. Is Duloxit a steroid?

No. Duloxit is not a steroid. It belongs to the anti-depressant class of drugs, more specifically SNRI (Serotonin-Norepinephrine Reuptake Inhibitor). It works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the nervous system.

Q. Is Duloxit a blood thinner?

No. Duloxit is not a blood thinner. Blood thinners prevent the formation of harmful blood clots.

Q. Is Duloxit a stimulant?

No. Duloxit is not a stimulant. Stimulants are the medicines which activate the central nervous system.

Q. Is Duloxit a pain killer?

No. Duloxit is not a classical painkiller e.g. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).Duloxetine is used for the treatment of chronic pain conditions like neuropathic pain, diabetic neuropathy or fibromyalgia.

Q. Is Duloxit a tricyclic antidepressant (TCA)?

No. Duloxit is not a tricyclic antidepressant (TCA). It belongs to a class of anti-depressants called SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors).

Q. Is Duloxit a benzodiazepine?

No. Duloxit is not a benzodiazepine. It belongs to a class of anti-depressants called SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors). Benzodiazepines belong to the sedative-hypnotic class of drugs and include agents like diazepam, lorazepam, alprazolam etc.

Q. Is Duloxit a narcotic?

No. Duloxit is not a narcotic. It means it does not have habit-forming potential. Narcotics are the substance which can cause addiction and dependence.

Q. Is Duloxit a psychotropic?

Yes. A psychotropic is a medicine that affects mind, emotions, and behaviour. Duloxit, being an anti-depressant agent reduces the symptoms of depression and is a psychotropic agent.

Q. Can I take Duloxit if I have Hepatitis C virus infection?

Duloxit should be used with caution in patients with Hepatitis C virus infection. Cases of liver injury, including severe elevations of liver enzymes (>10-times upper limit of normal), hepatitis, and jaundice have been reported with Duloxit. Taking Duloxit increases the risk of liver toxicity and fatty liver in Hepatitis C virus-infected patients.<br>

Q. What is the peak plasma concentration [Cmax] of Duloxit?

The maximum plasma concentration [Cmax] of Duloxit is 6 hours post oral dose. Food taken with Duloxit may delay the time to reach the peak plasma concentration from 6 to 10 hours. This may marginally decrease the extent of absorption (approximately 11%).

Q. Can I take Duloxit with Vitamin D?

Yes. Duloxitcan be taken with vitamin D. It does not have any known interaction with Vitamin D.

Q. What is half life of Duloxit?

The elimination half-life of Duloxit ranges from 8 to 17 hours (mean 12 hours).

Q. Which is better in depression, Duloxit or fluoxetine?

Fluoxetine has not been found to be different in either tolerability or efficacy when compared with Duloxit in major depression. Duloxit is good for treating depression, anxiety and may help with chronic pain.

Q. Which is better Duloxit vs sertraline?

Duloxit and sertraline are found to be equally effective in the treatment of Major Depressive Disorder (MDD). Certain symptoms like agitation and anxiety are reduced better by sertraline. Duloxit has been found to be better than sertraline for neuropathic pain.

Q. Which is better for chronic pain, Duloxit or pregabalin?

In patients with fibromyalgia Duloxit is found to be better than pregabalin in reducing depressed mood. Pregabalin is better in reducing fatigue. Duloxit and pregabalin generally provide equally comparable pain relieving efficacy in the treatment of diabetic peripheral neuropathic pain (DPNP).

Q. Which is better Duloxit or fluoxetine?

Duloxit has been found to be better for the treatment of chronic pain than Fluoxetine. Fluoxetine is good for treating depression and anxiety.

Q. Which is better for depression, Duloxit or mirtazapine?

Currently, there is not enough information to firmly recommend one antidepressant over another. However, both these drugs have been found to be safe and efficacious in the treatment of depression.

Q. Which is better for depression, Duloxit or venlafaxine?

Currently, there is not enough information to firmly recommend one antidepressant over another. Many doctors favour Duloxit over venlafaxine when pain conditions coexist with depression.

Q. Is Duloxit a barbiturate?

No. Duloxit is not a barbiturate. Barbiturates belong to the Sedative-Hypnotic class of drugs and are likely to have abuse potential.

Q. When to take Duloxit?

Duloxit can cause difficulty in sleep (insomnia). Hence, it is advised to be taken in the morning than at night.

Q. When does Duloxit start working?

Usually, the action of Duloxit takes about three to four weeks to appear. Do not discontinue the therapy in between, thinking that it is not effective.

Q. How much dose of Duloxit can produce overdose?

Overdose can occur at a doses as low as 1000 mg. Signs and symptoms of overdose (duloxetine alone or in combination with other medicinal products) included somnolence, coma, serotonin syndrome, seizures, vomiting and tachycardia.

Q. How does Duloxit work in urinary incontinence?

Duloxit is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.

Q. Can I take Duloxit with amitriptyline?

It is better to avoid Duloxit and amitriptyline together. It can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.

Q. Can I take Duloxit with sertraline?

It is better to avoid Duloxit and sertraline together. It can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.

Q. Can I take Duloxit with tramadol?

Duloxit and tramadol together can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Please inform your doctor if you are taking any of these medicines before coming to him.

Q. Can I take Duloxit with bupropion?

Bupropion can cause inhibition of metabolism of Duloxit in the body, resulting in toxic effects of Duloxetine. The concomitant use of these two drugs can result in seizures. Mention it to your doctor if you are taking any of these medications from before.

Q. Which is better in diabetic neuropathy, duloxetine or pregabalin?

In patients with fibromyalgia, Duloxit is found to be better than pregabalin in reducing depressed mood. Pregabalin is better in reducing fatigue. Duloxit and pregabalin generally provide equally comparable pain relieving efficacy in the treatment of diabetic peripheral neuropathic pain (DPNP).

Q. Can Duloxit get me high?

No. Duloxit does not cause a high. It does not create a feeling of euphoria and has no recreational potential.

Q. Can I use Duloxit for arthritis?

Duloxit is not approved for the treatment of arthritis. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.

Q. Can I use Duloxit for sciatica?

No, Duloxit is not approved for the treatment of sciatica. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.

Q. Can I use Duloxit for obsessive-compulsive disorder (OCD)?

Obsessive-compulsive disorder (OCD) is a type anxiety disorder. It is approved for the treatment of obsessive-compulsive disorder. Research studies suggest that Duloxit may provide a significant reduction in symptoms for patients with obsessive-compulsive disorder.

Q. Can I use Duloxit for hot flashes?

No. Duloxit is not approved for use in hot flashes. It may be used in the treatment of depression in postmenopausal women suffering from menopausal vasomotor symptoms (hot flashes, night sweats) and insomnia.

Q. Can I use Duloxit for headaches?

No, Duloxetine is not approved for use in headaches. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.

Q. Can I use Duloxit for a migraine?

No. Duloxit is not approved for use in a migraine. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.

Q. Can I use Duloxit for chronic pain?

Duloxit is approved for the treatment of chronic pain states including neuropathic pain (nerve pain) associated with Diabetes Mellitus and fibromyalgia.

Q. Can I use Duloxit for nerve pain?

Yes. Duloxit is approved for use in nerve pain or neuropathic pain conditions, most commonly seen in patients suffering from Diabetes Mellitus.

Q. Can Duloxit raise blood sugar levels?

No. Duloxit may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.
Related Lab Tests

Related Ayurvedic Ingredients

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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10 Tablet EC in 1 strip
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