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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated:
21 Sep 2020 | 12:55 PM (IST)
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Doxobin 10mg Injection

Prescription Required
Manufacturer
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Introduction

Doxobin 10mg Injection is used in the treatment of various types of cancers of blood, breast, lung, ovaries and soft tissues. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.

It is given as a drip or infusion vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life-threatening. Regular blood tests are required to monitor your blood cells along with the kidney, liver, and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have severe liver or heart-related problems, or if you are pregnant, or breastfeeding.  Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Uses of Doxobin Injection

Side effects of Doxobin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Doxobin

  • Vomiting
  • Allergic reaction
  • Nausea
  • Mouth sore
  • Hair loss
  • Stomach pain
  • Eye disorder
  • Increased thirst
  • Arrhythmia (irregular heartbeats)
  • Nail disorder

How to use Doxobin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Doxobin Injection works

Doxobin 10mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Doxobin 10mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Doxobin 10mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Doxobin 10mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Doxobin 10mg Injection may cause side effects which could affect your ability to drive.
As there is a frequent occurrence of nausea and vomiting with Doxobin 10mg Injection so driving should be discouraged.
Kidney
SAFE IF PRESCRIBED
Doxobin 10mg Injection is safe to use in patients with kidney disease. No dose adjustment of Doxobin 10mg Injection is recommended.
However, inform your doctor if you have any kidney disease.
Liver
CAUTION
Doxobin 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Doxobin 10mg Injection may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Doxobin 10mg Injection
₹39.6/ml of Injection
Duxocin 10mg Injection
Biochem Pharmaceutical Industries
₹21.86/ml of Injection
save 45%
Doxutec 10mg Injection
United Biotech Pvt Ltd
₹34.43/ml of Injection
save 13%
Adrim 10mg Injection
Fresenius Kabi India Pvt Ltd
₹42.86/ml of Injection
8% costlier
₹82.67/ml of Injection
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Prubicin 10mg Injection
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₹180/Injection
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Quick Tips

  • Doxobin 10mg Injection is given as an injection into the vein under the supervision of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
  • Inform your doctor if you experience fever, chills, shortness of breath and swelling of face or lips. 

Fact Box

Chemical Class
Anthracycline Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS

Patient Concerns

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Bee sting below middle finger, on palm yesterday. Swelling and redness today after approx 20 hours. No pain, only itching.
Dr. Souvik Sardar
Dermatology
Visit emergency for an injection at that place Instant reliefTake tab teczine 10mg -1tab at bedtime for itching
After giving hucog injection and duphaston 10mg I will get pragancy or not
Dr. Pranay Gandhi
Sexology
if ur husbands semen is normal and u just face an ovulation problem, u will get pregnant. u must know that even for normal couple chances of getting pregnant after sex once is just 8%
arrow
Do you have any questions related to Doxobin 10mg Injection ?

FAQs

Q. How does doxorubicin work?

Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell

Q. Is doxorubicin a vesicant?

Yes doxorubicin is a vesicant (irritant).

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.
  4. Doxorubicin hydrochloride. Sandwich, Kent: Pfizer Limited; 2009 [revised Feb. 2016]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Biological E. Limited, Road No. 35,Jubilee Hills, Hyderabad, Telangana -500033
Best Price
₹168.3
MRP198  Get 15% OFF
Valid only on the orders above ₹499
5 ml in 1 vial
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