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MD (Pharmacology), MBBS
Last updated on:
16 Jul 2019 | 04:58 PM (IST)
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Doxiglan 50 mg Injection


Overview

Uses of Doxiglan Injection

Doxiglan Injection side effects

Common
  • Vomiting
  • Allergic reaction
  • Nausea
  • Loss of appetite
  • Mouth sore
  • Hair loss
  • Stomach pain
  • Diarrhea
  • Eye disorder
  • Increased thirst
  • Heart beat irregular
  • Nail disorder

How to use Doxiglan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Doxiglan Injection works

Doxiglan 50 mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Doxiglan Injection related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Doxiglan 50 mg Injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lactation
UNSAFE
Doxiglan 50 mg Injection is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Driving
Do not drive unless you are feeling well.
As there is a frequent occurrence of nausea and vomiting with Doxiglan 50 mg Injection so driving should be discouraged.
Kidney
SAFE
Doxiglan 50 mg Injection is safe to use in patients with kidney disease. No dose adjustment of Doxiglan 50 mg Injection is recommended.
However, inform your doctor if you have any kidney disease.
Liver
CAUTION
Doxiglan 50 mg Injection should be used with caution in patients with liver disease. Dose adjustment of Doxiglan 50 mg Injection may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Doxiglan 50 mg Injection
Doxutec 50mg Injection
United Biotech Pvt Ltd
₹29.96/ml of Injection
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Doxorex 50mg Injection
Samarth Life Sciences Pvt Ltd
₹10.48/ml of Injection
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₹874.39/Injection
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Doxoruba 50mg Injection
Getwell Oncology Pvt Ltd
₹39.32/ml of Injection
save 96%
Doxilyd 50mg Injection
Celon Laboratories Ltd
₹523.81/Injection
save 48%

Expert Advice

  • Inform your doctor if you have a history of heart problems or low production of blood cells from the bone marrow.
  • Inform your doctor if you have received doxorubicin or any other anthracycline as anti-cancer therapy or radiation to the upper body.
  • You may need to perform blood count, heart/kidney/liver function tests before therapy.
  • Take precaution while taking doxorubicin as you may develop infection and bleeding episodes.
  • This therapy may cause damage to heart muscle or heart failure, the risk is more if radiation was used as treatment before for upper body.
  • Doxorubicin therapy causes high levels of uric acid in blood, also urine may turn red on therapy and this is not a sign of any damage. 
  • Live or attenuated vaccines (like polio, malaria) should not be taken during therapy and contact with persons who receive them must be avoided.
  • Women who are planning to become pregnant should be counselled about the toxic effect of this drug on babies. They should use two effective methods of contraception while on this therapy and 6 months after stopping it.
  • Men who are going to use this therapy should not father a child while on this therapy and 6 months post it. They should also seek guidance and counselling on sperm conservation before taking this therapy.
  • Do not drive or operate machinery as doxorubicin may cause nausea and vomiting.

Patient Concerns

Questions Related to Doxiglan

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suggest any medicine to recover from low haemoglobin .I have blood cancer and heart problems too. My haemoglobin remains between 8 - 10 .Suggest me some remedy to rise and maintain the minimum haemoglobin of 12 ?
Dr. Aanchal Maheshwari
Ayurveda
Regularly take kwath of bhuiamla 20 ml twice, tablet abhrlauh 20 ml twice after meal
Medicine for first stage blood cancer
Dr. Deepak Kumar Soni
Skin Specialist
Need to consult face to face , kindly consult to ayurvedic doctor at your local city.
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Do you have any questions related to Doxiglan 50 mg Injection?

FAQs

Q. How does doxorubicin work?

Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell

Q. Is doxorubicin a vesicant?

Yes doxorubicin is a vesicant (irritant).

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.
  4. Doxorubicin hydrochloride. Sandwich, Kent: Pfizer Limited; 2009 [revised Feb. 2016]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Gland Pharma Limited, 6-3-865/1/2, Greenland Apartments, Ameerpet, Hyderabad - 500016, India
Best Price
₹799.2
MRP999  Get 20% OFF
1 Injection in 1 vial
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