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MRP: Rs. 401.82 for 1 bottle(s) (50 ML infusion each)
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Composition for DOFUSE

Dobutamine(250 mg)

food interaction for DOFUSE

alcohol interaction for DOFUSE

pregnancy interaction for DOFUSE

lactation interaction for DOFUSE

It can be taken with or without food, but it is better to take Dofuse 250mg infusion at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Dofuse 250mg infusion is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Dobutamine(250 mg)


Dofuse 250mg infusion is used in both adults and children as short term treatment to improve heart function and output in condition such as heart failure, myocardial infarction, open heart surgery, cardiomyopathies, septic shock and cardiogenic shock. It is also used to improve heart output during positive end expiratory pressure (PEEP) ventilation, heart failure due to low blood pressures (hypotension).

How it works

Dofuse 250mg infusion belongs to a group of medicines called ionotropic agents that stimulate the beta-1 receptors in the heart. It strengthens the heart muscles, increases blood flow to the heart and improves the pumping of the heart.

Common side effects

Nausea, Altered heart rate, Bronchospasm, Chest pain, Blood clotting disorder, Shortness of breath, Fever, Fluctuating blood pressure, Frequent urge to urinate, Headache, Injection site inflammation, Narrowing of blood vessels, Rash, Tachycardia


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Expert advice for DOFUSE

  • Do not drive or operate machinery while on dobutamine treatment.
  • Seek medical advice for correction of hypovolemia with suitable volume expanders before treatment with dobutamine hydrochloride.
  • You may be monitored for ECG and blood pressure continuously during the therapy.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions for DOFUSE


Q. Is dobutamine a pressor/ vasopressor?
Yes, dobutamine is a vasopressor (agent that causes vasoconstriction of the blood vessels).
Q. Is dobutamine a beta blocker?
No, dobutamine is a beta agonist, not a beta blocker.
Q. Is dobutamine an inotrope/ positive inotrope?
Yes, dobutamine is an inotrope.
Q. Is dobutamine a catecholamine?
Yes, dobutamine is a catecholamine
Q. Is dobutamine a vasodilator?
Dobutamine has got both vasoconstrictor and vasodilator properties. The net effect depends on the tone of blood vessels and the disease condition.
Q. Is dobutamine a vesicant?
Yes, dobutamine is a vesicant (it may cause tissue blistering if it leaks out of the vein).
Q. Is dobutamine the same as dopamine?
Dopamine is a natural neurotransmitter present in the body; both dopamine and dobutamine are inotropic and stimulate the beta-1 receptors of the heart.
Q. Does dobutamine increase heart rate/ tachycardia?
Yes, increase in heart rate also known as tachycardia is a common side effect of dobutamine.
Q. Does dobutamine decrease afterload/ preload?
No, dobutamine does not have effects on afterload or preload.
Q. Does dobutamine increased stroke volume?
Yes, dobutamine is known to increase stoke volume.
Q. Does dobutamine cause an increase/decrease in blood pressure?
Yes, dobutamine may cause fluctuations in blood pressure.
Q. Does dobutamine increase urine output?
Yes, dobutamine is known to cause an increase in urine output.


Content on this page was last updated on 09 May, 2014, by Dr. Varun Gupta (MD Pharmacology)