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Composition for DNS (SKKL)

Dextrose(5%),Sodium Chloride(0.45%)

food interaction for DNS (SKKL)

alcohol interaction for DNS (SKKL)

pregnancy interaction for DNS (SKKL)

lactation interaction for DNS (SKKL)

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Dns 5%/0.45% infusion may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Carbohydrate depletion, dehydration, energy source, fluid depletion, hypoglycaemia, water replacement.

How it works

Dextrose provide calories and are a source of water for hydration. These solutions are capable of inducing diuresis depending on the clinical condition of the patient. Dextrose is readily metabolized, may decrease losses of body protein and nitrogen, promotes glycogen deposition and decreases or prevents ketosis if sufficient doses are provided.

Common side effects

Paresthesia (tingling or pricking sensation), Anaphylactic reaction, Convulsion, Diabetes, Decreased potassium level in blood, Decreased magnesium level in blood, Decreased phosphate level in blood, Inflammation of vein due to blood clot in the blood vessels, Injection site pain, Water intoxication
Sodium Chloride(0.45%)


Sodium chloride is used as a source of electrolytes (minerals in body fluids) and water to prevent dehydration (when loss of water exceeds water intake) and replenish the loss of sodium from body fluids in conditions like metabolic alkalosis (acid-base imbalance in body fluids that can cause serious complications) or diarrhea. It is also used as a solvent for reconstitution of medications or diluting agent for administration of medications intravenously.

How it works

Sodium chloride belongs to the class of medications called electrolytes or osmotic agents. It works by controlling fluid and electrolyte balance and increases water retention (by regulating osmotic pressure), thereby increasing water content in the body. It also plays an important role in maintenance of acid-base balance of body fluids. 

Common side effects

Application site redness of skin, Application site irritation, Increased sodium level in blood, Decreased sodium level in blood, Injection-site reactions, Injection site swelling, Chills, Fever


1 Substitutes
Sorted By
  • D.N.S 5%/0.45% INFUSION
    (1000 ML infusion in bottle)
    Baxter India Pvt Ltd
    Rs. 0.02/ML of infusion
    Rs. 19.61
    save 47% more per ML of infusion


Content on this page was last updated on 26 October, 2014, by Dr. Varun Gupta (MD Pharmacology)