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MRP: Rs. 19.47 for 1 strip(s) (10 tablets each)
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Composition for DIAPYRIN

Aspirin(ASA)(250 mg),Paracetamol(250 mg),Codeine(5 mg)

food interaction for DIAPYRIN

alcohol interaction for DIAPYRIN

pregnancy interaction for DIAPYRIN

lactation interaction for DIAPYRIN

There is no data available. Please consult doctor before consuming the drug.
Diapyrin 250mg/250mg/5mg tablet may cause excessive drowsiness and calmness with alcohol.
Taking Aspirin with alcohol increases the associated risk of stomach bleeding.
Diapyrin 250mg/250mg/5mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Diapyrin 250mg/250mg/5mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Aspirin(ASA)(250 mg)


Aspirin is used to treat pain including headache, migraine, neuralgia, toothache, sore throat, pain in joints, period pains and to reduce fever. It is also used as an anti-platelet agent (blood thinner) to decrease chances of heart attack in patients.

How it works

Aspirin (acetyl salicylic acid) is a nonsteroidal anti-inflammatory drug. Aspirin reduces the production of a chemical (prostaglandin) in the body by blocking the enzyme that makes prostaglandins (cyclooxygenase). Therefore,  swelling, pain, and fever are reduced. This also helps in blood thinning and in preventing clotting.

Common side effects

Nausea, Bronchoconstriction (constriction of air passages), Angioedema (swelling of deeper layers of skin), Bleeding, Cerebral hemorrhage, Dizziness, Shortness of breath, Gastrointestinal discomfort, Gastric erosion, Gastric ulcer, Gastrointestinal bleeding, Hepatitis (viral infection of liver), Enlarged liver, Indigestion, Respiratory alkalosis, Running nose, Ringing in ear, Urticaria, Vertigo, Vomiting
Paracetamol(250 mg)


Paracetamol is used for the relief of mild to moderate pain in conditions such as headache (including migraine), toothache, ear pain, joint pain, pain during menstruation, fever, feverish colds, and flu.

How it works

Paracetamol belongs to class of medications called analgesics (painkiller) and antipyretics (fever reducing). Paracetamol reduces pain by increasing the pain threshold. It reduces fever by acting on the temperature-regulating region of brain, resulting in increased blood flow across the skin, sweating and heat loss.

Common side effects

Skin redness, Allergic reaction, Shortness of breath, Running nose, Nausea, Liver injury, Abnormal blood cell count, Facial swelling, Blisters on skin
Codeine(5 mg)


Codeine is used for the treatment of mild to moderate pain, diarrhea, cough, irritable bowel syndrome.

How it works

Codeine belongs to a class of medications called opiate (narcotic) analgesics and to a class of medications called antitussives. When codeine is used to treat pain, it works by changing the way the brain and nervous system respond to pain. When codeine is used to reduce coughing, it works by decreasing the activity in the part of the brain that causes coughing.

Common side effects

Cns stimulation, Confusion, Constipation, Dizziness, Drowsiness, Headache, Decreased blood pressure, Lightheadedness, Feeling of discomfort, Restlessness, Tachycardia


No substitutes found

Expert advice for DIAPYRIN

• Take the drug with food to lower the chances of an upset stomach
• Consult your doctor if you have ringing in ears, unusual bleeding or nausea or vomitting after taking this drug
• Do not take this drug if you have or had stomach ulcer. 
• Do not start or continue the aspirin tablets and consult your doctor:
          - If you are allergic (hypersensitive) to aspirin or any of the other ingredients of aspirin tablet.
          - If you have history of asthma, urticarial, rhinitis, hay fever, chronic respiratory diseases,nasal polyps or other sensitivity reaction precipitated by other non-steroidal anti-inflammatory agents.

Frequently asked questions for DIAPYRIN


 Q. Is aspirin same as disprin, ecosprin and loprin?
Yes. All the three brands (disprin, ecosprin and loprin) contain aspirin (acetylsalicylic acid) as main ingredient.
Q. Is ecosprin a beta blocker?
No. Ecosprin (aspirin) is a non-steroidal anti-inflammatory drug.
Q. Is aspirin/disprin good for hangover?
No. However, alcohol consumption with aspirin increases the risk of bleeding.
Q. Is ecosprin a blood thinner?
Yes. Ecosprin (aspirin) reduces the effect of certain chemical messenger systems in the body. These compounds are responsible for platelet (thrombocyte) aggregation or blood clotting. Consequently, Aspirin may considerably reduce the risk of clots.
Q. Is aspirin/dispirin good for heart?
Yes. Aspirin at low dose generally prescribed to prevent and treat heart attacks. Patient should take a daily aspirin only if your doctor advises you to do so.
Q. Is aspirin good for hair growth?
No. Aspirin has no role on hair growth.
Q. Is aspirin safe?
Aspirin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.


Q. Is paracetamol safe/ banned/ available in India?
Paracetamol (also known as acetaminophen, crocin, dolo, calpol, pacimol) is an over-the-counter drug available in India. It is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is paracetamol a painkiller/ used for cold?
Paracetamol is used to relieve mild to moderate pain associated with cold and flu, as well as fever.
Q. Does paracetamol make you drowsy / sleepy? 
Paracetamol does not cause drowsiness. However, paracetamol is available in combination with cough and cold medicines (eg. cetirizine, chlorpheniramine), which may cause drowsiness or sleepiness.
Q. Is paracetamol an NSAID/ antibiotic?
Paracetamol is a anti-pyretic (anti-fever), anti -inflammatory drug, which belongs to the category of non-steroidal anti-inflammatory drug (NSAID). However, unlike other NSAIDS, paracetamol can relieve only mild to moderate pain.
It is not an antibiotic.
Q. Can I take crocin with cetirizine/ aceclofenac/ amoxicillin/ codeine/ tramadol/ warfarin/ erythromycin/ antibiotics?
Yes, paracetamol (available as crocin) can be taken with all of these drugs. Caution is advised when crocin is to be used with warfarin. However, always consult your doctor regarding combined use of crocin with any other drug.
Q. Can I take crocin with ibuprofen/naproxen/other NSAID?
Paracetamol (available as crocin) is available over-the-counter in combination with ibuprofen/naproxen/other NSAID. However, always consult your doctor regarding combined use of crocin with any other drug.
Q. Does paracetamol cause death?
Paracetamol on overdose can severely damage the liver and cause death. No more than 4 grams should be consumed in one day. Always consult your doctor regarding use of paracetamol.
Q. Can calpol make babies/ toddlers sleep/ help in teething pain?
Calpol can relieve pain in infants and children; it does not make them sleep.


Q.Is codeine legal in India?
Yes, however codeine containing tablets require prescription in India.
Q. Is codeine addictive?
Codeine may cause addiction when consumed for longer duration. Patients should follow the advice of the doctor regarding its use.
Q. Is codeine a narcotic/hydrocodone/morphine/depressant?
Codeine is a naturally occurring form of morphine and called as narcotic. Hydrocodone is derived form of codeine. Codeine is not a depressant drug.
Q. Is codeine strong?
It depends on the dose. Patients should follow the advice of the doctor regarding its use.
Q. Is codeine/Corex/Phensedyl over the counter or banned in India?
No, it is available in India with doctor’s prescription only.
Q. Is codeine/Corex bad or harmful?
It is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is Corex a drug?
No, Corex is a cough syrup which contains codeine as one of its component.
Q. What is Paracodin/Paracodin tablets/Paracodin 10 mg/Paracodol/Paracodina/Paracodin drops/Phensedyl/Phensedyl cough syrup used for?
These are the trade names of codeine containing products. Your doctor may prescribe it (depending on the disease condition) for the treatment of mild to moderate pain, diarrhea, cough, irritable bowel syndrome.
Q. Can I take codeine for flu/headache/toothache/cold/back pain/tonsillitis/migraine/menstrual cramps/stomach pain?
Codeine is specifically used for the treatment of mild to moderate pain, diarrhea, cough, irritable bowel syndrome. Patients should follow the advice of the doctor regarding its use.
Q. Can I take codeine with naproxen/paracetamol/ibuprofen/advil/ warfarin/metronidazole/hydrocodone/diclofenac/ amoxicillin?
You can take codeine with paracetamol/ibuprofen/ Advil/ warfarin/ diclofenac/amoxicillin/naproxen. Taking metronidazole and hydrocodone may alter the effects of codeine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does codeine expire?
Codeine containing tablets are available with mention of expiry date on it. Before taking medicine, patient should consult pharmacist or doctor.
Q. Does codeine make you high/tired/fat/awake/ sleep/constipate/thin blood/headache?
Codeine causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects.
Q. Does codeine have acetaminophen in it?
No, it does not contain acetaminophen in it. However, your doctor may prescribe codeine along with acetaminophen.


Content on this page was last updated on 22 February, 2015, by Dr. Varun Gupta (MD Pharmacology)