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Glimepiride(2 mg),Metformin(1000 mg)


Glimepiride(2 mg)


Glimepiride is used to lower the blood sugar levels in type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate.

How it works

Glimepiride belongs to a blood sugar lowering group of medicines called sulfonylurea. Glimepiride increases the amount of insulin released by the pancreas, and thereby decreases the blood sugar level.

Common side effects

anaemia., restlessness, Low blood sugar level symptoms headache, abnormal blood counts, problems with sleeping, sluggishness, dizziness, hunger pangs, as well as weight gain, vomitting

Metformin(1000 mg)


Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.

How it works

Metformin belongs to class of medications called antidiabetics.It decreases the amount of glucose absorbed from the food and the amount ofglucose made by liver. Metformin also increases the body's response to insulin(a natural substance that controls the amount of glucose in the blood).

Common side effects

malabsorption of vitamin B12, Nausea, taste disturbance, vomiting, Lactic acidosis, diarrhea, skin reactions., abdominal pain and loss of appetite


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Expert advice

  • Take glimepiride just before or with the first main meal of the day.
  • Do not skip any meal while taking glimepiride.
  • Swallow the glimepiride tablet without crushing or chewing with at least half a glass of water.
  • Do not take glimepiride if you are allergic to  glimepiride, other sulfonylureas, sulfonamides
  • Glimepiride tablets should not be given to children and adolescents under 18 years of age.

Frequently asked questions


Q. The drug is not safe during breast feeding.Is glimepiride safe?
Glimepiride is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q. Is glimepiride a generic drug?
Yes, glimepiride is a generic drug sold under several pharmaceutical brand names (Amaryl, Zoryl, etc.).

Q. Can I take glimepiride with metformin or insulin?
Glimepiride may be given in combination with metformin and/or insulin depending on your medical condition and as prescribed by the doctor.

Q. Does glimepiride cause fluctuations in weight,diarrhea, hair loss, erectile dysfunction, swelling, constipation?
Glimepiride is reported to cause low blood sugar level,weight gain, and swelling, but is not reported to cause diarrhea, constipation, hair loss, or erectile dysfunction.

Q. Is glimepiride a fast acting sulfa drug?
Glimepiride is a medium- to long-acting sulfonylurea drug against type 2 diabetes mellitus (action lasts for 24 hours). Its maximum effect is seen after 2-3 hours of drug intake.

Q. Is glimepiride same as glipizide, glyburide, metformin, or insulin?
They are not same. Glimepiride, glipizide and glyburide belong to the same class of drugs called sulfonylureas. Metformin belong to class called biguanides.Glimepiride causes release of insulin but it is not insulin.It should only be used if no other alternative drug is available. Please follow your doctor's advice regarding its use.


Q. Is Metformin a birth control pill/ insulin / statin/ banned drug?
Metformin (also available as glyciphage, glycomet, glycomet SR) is an antidiabetic drug used in treatment of type 2 diabetes mellitus, particularly in overweight patients, as an adjunct to the diet and exercise.

Q. Is metformin safe?
Metformin is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q. Can I take metformin forever?
Metformin should be taken at prescribed doses for the prescribed duration as advised by your doctor.

Q. Is metformin good for weight loss / weight loss in non-diabetics?
Metformin is used for the treatment of type 2 diabetes mellitus, particularly in overweight patients. 

Q. How long can I take metformin for PCOS / PCOS while pregnancy?
Metformin sometimes used to treat women with polycystic ovary syndrome (PCOS). Continuing metformin during pregnancy decreases the chances of developing gestational diabetes. It also reduces the risk of early pregnancy loss, preterm labor and prevention of fetal growth restriction. Depending on your medical history, your doctor might encourage you to continue metformin during pregnancy, or advice you to stop taking it. Always consult your doctor regarding its use.

Q. Does metformin help conceiving / help ovulation / help getting pregnant?
Women with PCOS who are treated with metformin have a better chance of getting pregnant. Always consult your doctor regarding its use.

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