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food interaction for DIAKIT 4

alcohol interaction for DIAKIT 4

pregnancy interaction for DIAKIT 4

lactation interaction for DIAKIT 4

Avoid Diakit 4 tablet with grapefruit juice.
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.
Taking glimepiride with alcohol may affect blood glucose levels in patients with diabetes.
Taking Atorvastation with alcohol may increase the risk of liver damage.
Diakit 4 tablet is highly unsafe in women who are or may become pregnant.
Human and animal studies have shown significant adverse effects on the fetus and should not be given under any circumstances. Please consult your doctor.
Diakit 4 tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Metformin(1 mg)


Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.

How it works

Metformin belongs to class of medications called antidiabetics.It decreases the amount of glucose absorbed from the food and the amount ofglucose made by liver. Metformin also increases the body's response to insulin(a natural substance that controls the amount of glucose in the blood).

Common side effects

Flatulence, Muscle pain, Abdominal bloating, Chest pain, Skin rash, Flushing, Abdominal pain, Nail disorder, Diarrhoea, Headache, Indigestion, Bitter taste, Constipation, Allergic reaction, Heartburn
Glimepiride(500 mg)


Glimepiride is used to lower the blood sugar levels in type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate.

How it works

Glimepiride belongs to a blood sugar lowering group of medicines called sulfonylurea. Glimepiride increases the amount of insulin released by the pancreas, and thereby decreases the blood sugar level.

Common side effects

Nausea, Diarrhoea, Bruise, Bleeding, Blood in stool, Dark colored urine, Dizziness, Sore throat, Stomach pain / epigastric pain, Yellow discoloration of skin, Yellow discoloration of eye, Weakness, Fever
Atorvastatin(10 mg)


Atorvastatin is used to treat patients with elevated cholesterol, triglyceride or lipoprotein levels in blood, and to reduce the risk of heart diseases, even when blood cholesterol is normal.

How it works

Atorvastatin blocks the action of the enzyme (HMG-CoA reductase) that is required for the production of cholesterol in the body. It thus lowers the level of blood lipids such as cholesterol and triglycerides.

Common side effects

Joint pain, Memory impairment, Confusion, Diarrhoea, Fatigue, Fever, Heartburn, Indigestion, Muscle pain, Nausea, Weakness


Ramipril is mainly used to control high blood pressure (hypertension). It is used to treat heart failure, to improve survival after heart attack and to prevent stroke. Ramipril is also used to treat various kidney diseases.

How it works

Ramipril belongs to a class of drugs called ACE inhibitors (angiotensin converting enzyme inhibitors), Ramipril inhibits the chemical ACE (angiotensin converting enzyme). As a result, there is relaxation of blood vessels leading to a fall in blood pressure which makes it easier for the heart to pump blood.

Common side effects

Allergic reaction, Cough, Dizziness, Difficulty in swalloing, Shortness of breath, Facial swelling, Generalised swelling, Headache, Vomiting, Stomach upset


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Expert advice for DIAKIT 4

  • Take the medicine with food to avoid upset stomach.
  • Check your blood sugar regularly.
  • Do not take metformin in severe diarrhoea or vomiting, or when starting antihypertensive or diuretic therapy or therapy with a non-steroidal anti-inflammatory drug (NSAID).
  • This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal).
  • Lactic acidosis can start slowly and get worse over time.
  • Consult your doctor immediately if you have even mild symptoms of lactic acidosis, such as:muscle pain or weakness,numb or cold  arms and legs,trouble breathing,feeling dizzy, stomach pain, nausea, vomiting, slow heart rate.
  • Do not take metformin if you need to have any type of x-ray or CT scan using a dye
  • You need to get certain kidney function tests done before starting treatment  with metformin and regularly thereafter.
  • Be careful when taking this drug in combination with insulin or other oral antidiabetics, as it may lead to low  blood glucose level (hypoglycemia).

Frequently asked questions for DIAKIT 4


Q. Is Metformin a birth control pill/ insulin / statin/ banned drug?
Metformin (also available as glyciphage, glycomet, glycomet SR) is an antidiabetic drug used in treatment of type 2 diabetes mellitus, particularly in overweight patients, as an adjunct to the diet and exercise.
Q. Is metformin safe?
Metformin is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Can I take metformin forever?
Metformin should be taken at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is metformin good for weight loss / weight loss in non-diabetics?
Metformin is used for the treatment of type 2 diabetes mellitus, particularly in overweight patients. 


 Q. Is glimepiride a generic drug?
Yes, glimepiride is a generic drug sold under several pharmaceutical brand names (Amaryl, Zoryl, etc.).
Q. Can I take glimepiride with metformin or insulin?
Glimepiride may be given in combination with metformin and/or insulin depending on your medical condition and as prescribed by the doctor.
Q. Does glimepiride cause fluctuations in weight,diarrhea, hair loss, erectile dysfunction, swelling, constipation?
Glimepiride is reported to cause low blood sugar level,weight gain, and swelling, but is not reported to cause diarrhea, constipation, hair loss, or erectile dysfunction.
Q. Is glimepiride a fast acting sulfa drug?
Glimepiride is a medium- to long-acting sulfonylurea drug against type 2 diabetes mellitus (action lasts for 24 hours). Its maximum effect is seen after 2-3 hours of drug intake.
Q. Is glimepiride same as glipizide, glyburide, metformin, or insulin?
They are not same. Glimepiride, glipizide and glyburide belong to the same class of drugs called sulfonylureas. Metformin belong to class called biguanides.Glimepiride causes release of insulin but it is not insulin.It should only be used if no other alternative drug is available. Please follow your doctor's advice regarding its use.


Q. What is tonact tg/ tonact 10/ tonact 40/ tonact 20/ storvas 10/ storvas 20/ lipikind/ atorlip/ atorlip-20?
   Atorvastatin (also available as tonact tg/ tonact 10/ tonact 40/ tonact 20/ storvas 10/ storvas   20/ lipikind/ atorlip/ atorlip-20) belong to group of medications called statins (lipid-lowering      agents) or HMG CoA reductase inhibitors. It acts by blocking the enzyme HMG CoA          reductase and formation of cholesterol, thus, lowering the blood lipid levels.

Q. Is atorvastatin same as simvastatin/ pravastatin?   
Atorvastatin and simvastatin/ pravastatin belong to same class of medication called as HMG     CoA reductase inhibitor (or statins) with similar action but their effect may vary upon individual response.

Q. Is atorvastatin diuretic/ beta blocker/ ace inhibitor?
  No. Atorvastatin belongs to class of medication called as HMG CoA reductase inhibitor or     statins.

Q. It atorvastatin gluten free?  
Yes. It is gluten free. Please refer to package insert of the prescribed brand before use.

Q. Is it a blood thinner? 
   No. it is a lipid lowering drug.

Q. Is atorvastatin better than simvastatin/ pravastatin?  
   Atorvastatin and simvastatin/ pravastatin belong to same category of medications with        similar action, but their effect may vary upon individual response. Always consult your doctor regarding its use.


Q. Is ramipril a diuretic?
No, ramipril is not a diuretic It belongs to a class of drugs called ACE inhibitors (angiotensin converting enzyme inhibitors), mainly used to reduce high blood pressure.
Q. Is ramipril safe?
Ramipril is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is ramipril or cardace a calcium channel blocker/alpha blocker/ beta blocker?
No, ramipril or cardace is an ACE inhibitor and shows no known effects on calcium channels or alpha receptors or beta receptors.
Q. Is ramipril a nitrate or a statin?
Ramipril is neither a nitrate nor a statin. It is an ACE inhibitor used to treat high blood pressure.
Q. What are Cardace / Ramistar/Hopace used for?
Cardace, Ramistar, Hopace are all trade names for the active drug ramipril. Ramipril is an ACE inhibitor used to treat high blood pressure.
Q. Can I take ramipril with simvastatin/amlodipine/ Viagra/naproxen/prednisolone/ metformin/ Sudafed (pseudoephedrine-decongestant preparation)?
There are no known serious drug interactions between ramipril when taken with simvastatin/ amlodipine/ Viagra/naproxen/prednisolone/ metformin/Sudafed. However, consult your doctor about all medications currently taken before starting and while on ramipril.
Q. Can I take ramipril with ibuprofen?
Ibuprofen can be taken with ramipril, however, it is known that ibuprofen and other NSAIDs may reduce the antihypertensive effects of ramipril. Consult your doctor about any medications currently taken before starting and while on ramipril.
Q. Does ramipril cause coughing?
Yes, non-productive tickling cough, is one of the common side effects or ramipril.
Q. Does ramipril cause frequent urination?
No, ramipril has no known effect on increasing the frequency of urination. It may rarely increase the urine output but not affect the frequency of urination.
Q. Does ramipril cause itching?
Yes, ramipril may cause itching of skin. It is not very commonly observed.
Q. Does ramipril cause an increase in potassium levels in the blood?
Yes, increased potassium levels is one a common side effects of ramipril.
Q. Does ramipril cause depression?
Yes, ramipril may cause depression; however, it is not very commonly observed.
Q. Does ramipril thin the blood?
No. ramipril has no known effect on blood thinning.
Q. Is ramipril available in India?
Yes, ramipril is available in India with more than 100 brand names.


Content on this page was last updated on 23 October, 2015, by Dr. Varun Gupta (MD Pharmacology)