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food interaction for DEFUNG

alcohol interaction for DEFUNG

pregnancy interaction for DEFUNG

lactation interaction for DEFUNG

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Defung tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
UNSAFE
Defung tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION for DEFUNG

Clotrimazole(20mg)

Uses

Clotrimazole is used in the treatment of fungal infections.

How it works

Clotrimazole acts against the fungi by impairing the permeability of the fungal cell wall and inhibits the activity of enzymes within the cell. It specifically inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production.

Common side effects

Application site reaction, Application site irritation, Burning sensation, Fever, Itching, Skin redness, Stomach pain, Stomach upset, Vaginal discharge, Vomiting
Miconazole(100mg)

Uses

Miconazole is used in the treatment of fungal infections.

How it works

Miconazole acts mainly by preventing the growth of fungi. It interacts with chemicals (cytochrome P-450) inside the fungus and prevents the synthesis of an essential component of fungal cell membrane (ergosterol); this results in increased cellular permeability causing leakage of cellular contents from fungal cell, ultimately preventing fungal growth. Miconazole possesses antifungal activity against dermatophytes and yeasts as well as antibacterial activity against certain gram-positive bacilli and cocci.

Common side effects

Abdominal pain, Burning sensation, Itching, Vaginal discharge, Vaginal irritation, Vaginal swelling, Fever
Tinidazole(500mg)

Uses

Tinidazole is used in the treatment of diarrhoea and bacterial infections.

How it works

Tinidazole belongs to a class of drugs called as nitroimidazole antibiotics that act against microbes like protozoa and anaerobic bacteria. It enters the cells of bacteria or protozoa, damages or interfere s in the production of their DNA; thereby killing them and reducing the infection.

Common side effects

Numbness, Abdominal pain, Acne-like rash, Facial swelling, Allergic reaction, Swelling of mouth, Lip swelling, Ankle swelling, Limb swelling, Constipation, Convulsion, Dizziness, Altered taste, Difficulty in swallowing, Shortness of breath, Fatigue, Headache, Hoarseness of voice, Loss of appetite, Stomach cramp, Stomach upset, Urticaria, Vomiting, Weakness

SUBSTITUTES for DEFUNG

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Expert advice for DEFUNG

  • Clotrimazole cream or pessary is for vaginal use only. Do not use in the eyes or take by mouth.
  • Apply to the affected area two or three times a day. Use the cream for at least 2 weeks. In some cases it may be necessary to continue to use the cream for more than 4 weeks.
  • For using this cream, squeeze a small amount onto your fingertip and gently apply to the irritated skin around the vagina.
  • If this product comes with one applicator do not throw it away after use. Separate the pieces of the applicator and wash with warm and soapy water immediately after use. Rinse thoroughly. Make sure the applicator is completely dry before the next use. If this product comes with 3 disposable applicators, throw away each applicator after use.
  • Wash your hands immediately after using the cream.
  • To clear up your infection completely, use this cream for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Frequently asked questions for DEFUNG

Clotrimazole

Q.Is clotrimazole a steroid/ used for thrush/ good for ringworm/ good for toenail fungus?
Clotrimazole is an antifungal medication and not a steroid. It is used for treating thrush, ringworm. It may be used for toenail fungus; however its efficacy in this case is not completely established. Patients should follow the advice of the doctor regarding its use

Q.Is clotrimazole available over the counter?
Yes, clotrimazole cream is available over the counter. But if this is the first time you have had vaginal itching and discomfort, talk with a physician before using clotrimazole

Q.Is clotrimazole better than miconazole?
Although clotrimazole and miconazole are different drugs, they work in similar ways. Both are used for treatment of fungal infection, primarily yeast. Despite these similarities, they are often used in different parts of the body and they have different active ingredients and so cannot be compared. Both medications work well, but one of them may work better for some people than others. Check with your doctor for more details

Q.Is candida a steroid/ curable/ contagious/ a STD/ dangerous/ curable/ a steroid cream/ infection dangerous?
Candida is a yeast, a form of fungus. It causes infections such as candidiasis or thrush in humans and other animals. Individuals with Candida infections are not usually contagious, though in some settings immunocompromised people can catch the infection. The infection does not usually spread by sexual contact. Candida infection is curable but if not treated early it can result in a serious infection

Q.Is canesten hydrocortisone for thrush?
Canesten HC cream contains two active ingredients, clotrimazole (antifungal medicine used to treat infections with fungi and yeasts) and hydrocortisone (corticosteroid medicine that is applied to the skin to relieve the symptoms of inflammation). It is used to treat vaginal thrush.

Miconazole

Q.Can miconazole/ Monistat be used for conditions for BV (bacterial vaginosis), ring worms, and urinary tract infections?
Yes, miconazole can be used for BV (bacterial vaginosis). It is used for treatment and prevention of fungal infections of the oral cavity, ring worms and superinfections due to gram-positive bacteria. Miconazole can be taken in rare fungal infections of the urinary tract

Q.Does miconazole cause burning sensation?
Yes, burning sensation on the skin and vaginal burning are common side effects of miconazole

Q.Does miconazole cause dry skin?
No, miconazole is not known to have the side effect to cause drying of skin

Q.Is miconazole safe for babies?
Yes, miconazole is safe for babies. It may be used in nappy rashes and oral fungal infections as advised by your doctor

Q.Is miconazole a steroid?
No, miconazole is not a steroid. It is an imidazole (organic compound) and belongs to class of antifungal agents

Q.Is miconazole same as ketoconazole?
Both miconazole and ketoconazole are antifungal medicines. However, they are prescribed for different type of fungal infections

Q.Can I take miconazole with fluconazole?
Taking two antifungal agents may have additive effect and have pronounced side effects. Patients should follow advice of the doctor regarding its use

Q.Does miconazole work for yeast infections?
Yes, miconazole works for oral and vaginal yeast infections

Q.Does miconazole expire?
Yes, antifungals like miconazole have an expiry date. Read instruction on the pack for the date of expiry

Q.Is miconazole an OTC (over the counter)?
No, miconazole cannot be bought over the counter. It needs prescription of a qualified doctor.

Tinidazole

Q.Is tinidazole or Fasigyn an antibiotic/sulfa drug?
Tinidazole is an antibiotic/anti-protozoal/anti-amoebic drug. It is not a sulfa drug

Q.Is tinidazole available or sold over the counter?
No. Tinidazole is a prescription drug. It is not available or sold over the counter

Q.Is tinidazole the same as metronidazole/Flagyl?
Tinidazole is different from metronidazole (also called as Flagyl). However, both of them belong to the same class of drugs

Q.Is tinidazole/Fasigyn safe?
Yes. Tinidazole is relatively safe if used as recommended. In case of any side-effects, consult your doctor

Q.What are Tiniba and Fasigyn used for?
Tiniba and Fasigyn are brand names of tinidazole available in the market. They are used for the same indications as tinidazole

Q.Can I take tinidazole with fluconazole/Tylenol/ibuprofen?
Tinidazole can be taken with fluconazole/Tylenol (paracetamol)/ibuprofen only if prescribed by your doctor

Q.Does tinidazole cure bacterial vaginosis and UTI?
Tinidazole is effective in the treatment of bacterial vaginosis. But it is not used for treatment of UTI

Q.Does tinidazole cause yeast infections/diarrhea/cancer?
Prolonged use of tinidazole may cause candida or yeast infections. There is no evidence of tinidazole causing cancer. If you experience any such symptoms, please consult your doctor

Q.Does tinidazole treat Chlamydial or urinary tract infections?
Yes. Tinidazole is used to treat Chlamydial infections, but is not effective for treating a urinary tract infection

Q.Does tinidazole affect birth control?
There is no evidence of tinidazole affecting birth control. Please consult your doctor to confirm whether you require a secondary birth control measure while taking tinidazole.

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Content on this page was last updated on 21 June, 2014, by Dr. Varun Gupta (MD Pharmacology)