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Definium 10mg Sublingual tablet
Prescription Required
Product introduction
Definium 10mg Sublingual tablet is used in the treatment of schizophrenia and mania. It can also be used to treat depression and bipolar disorders. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.
Definium 10mg Sublingual tablet is taken by mouth without food. However, it is advisable to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to the doctor as it may worsen your symptoms.
Some common side effects of this medicine include nausea, increased saliva production, and taste change. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight. However, modifying your lifestyle by having a healthy diet and doing exercise regularly can reduce this side effect.
Before taking this medicine it is important to inform the doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), or liver problems.
Definium 10mg Sublingual tablet is taken by mouth without food. However, it is advisable to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to the doctor as it may worsen your symptoms.
Some common side effects of this medicine include nausea, increased saliva production, and taste change. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight. However, modifying your lifestyle by having a healthy diet and doing exercise regularly can reduce this side effect.
Before taking this medicine it is important to inform the doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), or liver problems.
Uses of Definium Sublingual tablet
Benefits of Definium Sublingual tablet
In Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Definium 10mg Sublingual tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
In Mania
Mania means extremely excited or elevated mood. Definium 10mg Sublingual tablet helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Definium 10mg Sublingual tablet will ensure that you have a better social life and are able to do daily activities more comfortably.
Side effects of Definium Sublingual tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Definium
- Abnormal involuntary movements
- Anxiety
- Dizziness
- Dystonia (involuntary muscle contractions)
- Increased saliva production
- Nausea
- Parkinsonism
- Sleepiness
- Taste change
- Weight gain
How to use Definium Sublingual tablet
Place the tablet under the tongue or between the cheek and gum, and let it dissolve. Do not chew, crush, or swallow the tablet. Definium 10mg Sublingual tablet may be taken with or without food, but it is better to take it at a fixed time.
How Definium Sublingual tablet works
Definium 10mg Sublingual tablet is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Definium 10mg Sublingual tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Definium 10mg Sublingual tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Definium 10mg Sublingual tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Definium 10mg Sublingual tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Definium 10mg Sublingual tablet is safe to use in patients with kidney disease. No dose adjustment of Definium 10mg Sublingual tablet is recommended.
Limited information is available on use of Definium 10mg Sublingual tablet in patients with end stage kidney disease.
Limited information is available on use of Definium 10mg Sublingual tablet in patients with end stage kidney disease.
Liver
CAUTION
Definium 10mg Sublingual tablet should be used with caution in patients with liver disease. Dose adjustment of Definium 10mg Sublingual tablet may be needed. Please consult your doctor.
Use of Definium 10mg Sublingual tablet is not recommended in patients with severe liver disease.
Use of Definium 10mg Sublingual tablet is not recommended in patients with severe liver disease.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Definium 10mg Sublingual tablet should be taken as per dose and duration suggested by the doctor.
- It is advisable not to eat or drink anything for 10 minutes after taking the medicine.
Fact Box
Chemical Class
Dibenzoxepines Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Atypical Antipsychotics
Interaction with drugs
Taking Definium with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Clowil, Odis, Kamestin
Life-threatening
Brand(s): Geoflu, Con F, Fucan
Life-threatening
Brand(s): Itraspan, Itoz, Sitra
Life-threatening
Brand(s): Ketozoe
Life-threatening
Patient concerns
FAQs
Q. Why has Definium 10mg Sublingual tablet been prescribed?
Definium 10mg Sublingual tablet is an antipsychotic drug used to treat manic episodes and schizophrenia, a mood disorder. It shortens the time to recovery and prevents mania from returning.
Q. What is the right way to take Definium 10mg Sublingual tablet?
Place the tablet under the tongue until completely dissolved, this should take a few seconds. Do not chew or swallow the tablet, and do not eat or drink for 10 minutes after taking it—otherwise the medicine will not be absorbed completely and may not work properly.
Q. How many times a day can I take Definium 10mg Sublingual tablet?
Definium 10mg Sublingual tablet must be taken twice a day, once in the morning and once in the evening, e.g., after breakfast and dinner or as prescribed by your doctor.
Q. Does Definium 10mg Sublingual tablet have a local anesthetic effect?
Yes, this medicine can cause tingling or numbing of the tongue and mouth for up to an hour after each dose.
Q. How long does it take for Definium 10mg Sublingual tablet to work?
Like many medicines, Definium 10mg Sublingual tablet does not work straight away. You might start feeling more calm and relaxed after a few weeks of taking this medicine.
Q. Is Definium 10mg Sublingual tablet addictive?
This medicine is not addictive, but if you stop taking the medicine suddenly you may experience unpleasant physical feelings.
Q. Does Definium 10mg Sublingual tablet cause sleepiness?
Somnolence (sleepiness) is a common side effect of Definium 10mg Sublingual tablet. You should refrain from indulging in driving and heavy activities during your treatment. It is better to talk to your doctor if you experience sleep problems while taking Definium 10mg Sublingual tablet.
Q. Can I drink alcohol while taking Definium 10mg Sublingual tablet?
It is recommended that people taking this medicine should not drink alcohol. This is because<br>Definium 10mg Sublingual tablet is an antipsychotic and taking it with alcohol can cause severe drowsiness. This can lead to falls and accidents. Also, drinking alcohol may make mania, depression, and anxiety worse. Discuss any concerns you have with your doctor, pharmacist, or nurse.
Q. Does Definium 10mg Sublingual tablet affect blood sugar level?
If you have diabetes you may need to check your blood sugar (glucose) more frequently, as this medicine may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.
Q. I am experiencing a change in my taste after the start of the treatment with Definium 10mg Sublingual tablet. Any tips to reduce it?
A change in taste is a common side-effect of this medicine. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You may also add some extra flavor or seasonings to your food.
Q. Can I take fluoxetine with Definium 10mg Sublingual tablet?
No, you should avoid taking fluoxetine with Definium 10mg Sublingual tablet. This is because fluoxetine may cause an increase in levels of Definium 10mg Sublingual tablet in the body which may increase the medicine's side effects. Always consult your doctor before taking any other medications along with Definium 10mg Sublingual tablet. Self-medication can be risky.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Asenapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 65-70.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 87.
- Asenapine maleate. Everard Close, St Albans: Lundbeck Limited; 2010 [08 Feb. 2018]. [Accessed 04 Feb. 2019] (online) Available from:
- Drugs.com. Asenapine Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Asenapine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Marketer details
Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India
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