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MRP: Rs. 4190.47 for 1 vial(s) (1 injection each)
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Composition for DAPNAT

Daptomycin(350 mg)

food interaction for DAPNAT

alcohol interaction for DAPNAT

pregnancy interaction for DAPNAT

lactation interaction for DAPNAT

It can be taken with or without food, but it is better to take Dapnat 350mg injection at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Dapnat 350mg injection is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Daptomycin(350 mg)


Dapnat 350mg injection is used in adults to treat serious bacterial infections of the skin and underlying tissue and those in the blood (bacteremia) and tissues that line the cavities of the heart (endocardium).

How it works

Dapnat 350mg injection belongs to a class of antibiotics called the cyclic lipopeptides. It is an antibacterial agent that works by killing the bacteria or stopping their growth.

Common side effects

Nausea, Liver enzyme increased, Increased creatine phosphokinase level in blood, Abdominal pain, Altered sleep, Anemia, Anxiety, Fungal infection, Constipation, Increased blood pressure, Decreased blood pressure, Diarrhoea, Dizziness, Fever, Flatulence, Headache, Rash, Itching, Skin redness, Abdominal bloating, Swelling of abdomen, Urinary tract infection, Vomiting, Weakness


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Expert advice for DAPNAT

  • Do not skip any dose or discontinue this medicine, as it may increase your chances of developing drug resistance.
  • Tell your doctor if you experience symptoms of serious allergic reaction, such as wheezing, difficulty breathing, swelling of the face, neck and throat, rashes and hives, fever; any unusual tingling or numbness of the hands or feet, loss of feeling or difficulties with movements; bloody or watery diarrhea; signs of eosinophilic pneumonia such as new or worsening fever, cough or difficulty breathing.
  • This medicine can cause unusual results with certain medical tests (especially blood clotting test).
  • Your doctor will perform blood tests to monitor the health of your muscles both before you start treatment and frequently during treatment with daptomycin.

Frequently asked questions for DAPNAT


Q. Is daptomycin a penicillin/ nephrotoxic/ bactericidal/ a vesicant/an aminoglycoside/ vancomycin/ dialyzable/ bacteriostatic/ a macrolide/ latex free?
Daptomycin is not a penicillin, vancomycin, aminoglycoside, macrolide. It is a bactericidal not bacteriostatic agent. It shows slight nephrotoxicity. It is a vesicant and is latex free.
Q. Does daptomycin cover methicillin- resistant staphylococcus aureus (MRSA)/ pseudomonas/ streptococcus/anaerobes/ klebsiella?
Daptomycin exhibits rapid, bactericidal activity against Gram-positive organisms including Staphylococcus, Streptococcus, Enterococcus and isolates resistant to methicillin (MRSA), vancomycin, and linezolid. 
Q. Does daptomycin cross the blood-brain barrier/penetrate cerebrospinal fluid (CSF)?
Daptomycin does not cross the blood-brain barrier or penetrate CSF.
Q. Does daptomycin cause renal failure?
Daptomycin may result in renal toxicity in some cases. 
Q. Does daptomycin dialyzed out?
Yes. Daptomycin can be dialyzed out.


Content on this page was last updated on 05 June, 2015, by Dr. Varun Gupta (MD Pharmacology)