Dactinoget 0.5mg Injection

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store below 30°C

Introduction

Dactinoget 0.5mg Injection is used for the treatment of several kinds of cancer such as some kinds of cancer that affect the testicles (testicular cancer), uterus or womb (gestational trophoblastic neoplasia), kidneys (Wilms' tumor), bones and muscles (Ewing's sarcoma).

Dactinoget 0.5mg Injection works by interfering with the growth of cancer cells, which are eventually destroyed. It is given under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include nausea, vomiting, mouth ulcers and loss of appetite. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, and physical examinations both before and during treatment with this medicine.

Benefits of Dactinoget Powder for Injection

In Testicular cancer

Testicular cancer is the cancer in the male organs called testicles, that make male hormones and sperm. The testicles are located inside a loose bag of skin (scrotum) underneath the penis. Dactinoget 0.5mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. It is given as an injection by a doctor or nurse and should not be self-administered.

In Wilms' tumor

Wilms’ tumor, also known as nephroblastoma, is the most common cancer of the kidneys in children. Dactinoget 0.5mg Injection is used along with other other medicines or treatment modalities such as surgery, radiation or chemotherapy depending on the stage or severity of the cancer and the condition of the patient. Follow the doctor’s instructions carefully to get the most benefit.

In Gestational trophoblastic neoplasia

Gestational trophoblastic disease (GTD), is a rare tumor that develops inside the uterus from the tissue that forms after the female conceives (successful fusion of sperm and egg). Dactinoget 0.5mg Injection is given to kill such kinds of tumor cells and prevent their further growth. This medicine is given only under medical guidance. Consult your doctor if you have any doubts.

In Ewing's sarcoma

Exing’s sarcoma is a tumor that grows in your bones or the soft tissue around your bones, such as cartilage or the nerves. It usually affects children and young adults. Dactinoget 0.5mg Injection helps to treat Ewing’s sarcoma. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Dactinoget Powder for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dactinoget

  • Nausea
  • Vomiting
  • Loss of appetite
  • Glossitis (tongue inflammation)
  • Lip inflammation
  • Diarrhea
  • Inflammation of the rectum
  • Low blood platelets

How to use Dactinoget Powder for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dactinoget Powder for Injection works

Dactinoget 0.5mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dactinoget 0.5mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Dactinoget 0.5mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Dactinoget 0.5mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Dactinoget 0.5mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Dactinoget 0.5mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Dactinoget 0.5mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Dactinoget 0.5mg Injection in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Dactinoget 0.5mg Injection is given as an injection into vein under the supervision of a doctor only.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
  • Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and dark urine.

Fact Box

Chemical Class
Antitumor Antibiotics
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkaloids-cytotoxic agents

Patient Concerns

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Sir my first child suffered from wlims tumor. Now she is fine after treatment. Sir i want to know will my second child who is in mother womb can have such problems. Sir pls advise me what to do?
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Wilms tumor can be hereditaryGo for routine prenatal tests only
i'm patient of Ewing sarcoma bone cancer
Dr. Vijay Sharnangat
Medical Oncology and Hematology
How can I help you.
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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1712-13.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 348-49.
  3. Dactinomycin. Immeuble Le Wilson: Orphan Europe SARL; 2006 [revised Jun. 2013]. [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)
Country of Origin: India

Expires on or after: September, 2021

A licensed vendor partner from your nearest location will deliver Dactinoget 0.5mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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