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Composition FOR DABAZ

Dacarbazine(500 mg)

food interaction for DABAZ

alcohol interaction for DABAZ

pregnancy interaction for DABAZ

lactation interaction for DABAZ

It can be taken with or without food, but it is better to take Dabaz 500mg infusion at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Dabaz 500mg infusion may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Dabaz 500mg infusion is probably unsafe to use during breastfeeding. Please consult your doctor.


Dacarbazine(500 mg)


Dabaz 500mg infusion is used in the treatment of malignant melanoma and hodgkin’s disease.

How it works

Dabaz 500mg infusion works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Common side effects

Nausea, Vomiting, Anemia, Decreased white blood cell count, Loss of appetite


No substitutes found

Expert advice FOR DABAZ

  • Dacarbazine injection must be given under the supervision of a doctor who is experienced in giving chemotherapy medications for cancer.
  • You should not eat anything for 4 to 6 hours before taking dacarbazine injection. This may help prevent severe nausea or vomiting.
  • Dacarbazine may make your skin sensitive to sunlight. Avoid any unnecessary or prolonged exposure to sunlight and wear protective clothing, sunglasses, and sunscreen.
  • Dacarbazine can cause a severe decrease in the number of blood cells in your bone marrow increasing the risk of developing serious infection or bleeding. Consult your doctor immediately if you experience symptoms, such as, fever, sore throat, ongoing cough and congestion, or other signs of infection; unusual bleeding or bruising. 
  • Dacarbazine may cause serious or life-threatening liver damage. Consult your doctor immediately if you experience symptoms, such as nausea, extreme tiredness, unusual bleeding or bruising, lack of energy, loss of appetite, pain in the upper right part of the stomach, or yellowing of the skin or eyes.
  • It is advisable for men undergoing dacarbazine treatment to take contraceptive measures during and for 6 months after termination of therapy.
  • Do not drink alcohol while on dacarbazine treatment.
  • Do not drive or operate machines while using dacarbazine.

Frequently asked questions FOR DABAZ



How is dacarbazine administered/ how is dacarbazine given/ why is dacarbazine given as an infusion?
Dacarbazine is administered as infusion or injection. Absorption by mouth is slow and varies therefore intravenous (infusion or injection) administration is preferred


Is dacarbazine a vesicant?
Dacarbazine is a potent vesicant (it is corrosive), and it should be carefully administered to avoid the risk of extravasation (leaking into the tissues)


What is dacarbazine used for?
Dacarbazine is used to treat skin cancer that has spread to other parts of the body (malignant melanoma), cancer of the white blood cell (Hodgkin's lymphoma) and advanced adult soft tissue sarcomas (cancer of soft tissues such as muscles, tendons, fat, and blood vessels)

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Does dacarbazine work/ how effective is dacarbazine?
Dacarbazine is effective if taken at recommended dosage and duration as advised by your doctor


Does dacarbazine cause hair loss?
Yes. Hair loss is a common side effect of dacarbazine.


Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)