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MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Overview

Introduction

CX 5 Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection. It also protects the nerves from the side effects that may occur during the course of the treatment.

CX 5 Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of CX 5 Tablet

Side effects of CX 5 Tablet

Common
  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Watery eyes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice
  • Increased uric acid level in blood
  • Visual impairment

How to use CX 5 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. CX 5 Tablet is to be taken empty stomach.

How CX 5 Tablet works

CX 5 Tablet is a combination of five medicines: Rifampicin, isoniazid, ethambutol, pyrazinamide and vitamin B6 (pyridoxine) which treat tuberculosis (TB). Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents the these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide, on the other hand work by slowing the growth of these bacteria. Vitamin B6 (pyridoxine) is added to prevent nerve damage which may be a side effect of isoniazid.

Safety Advice

Alcohol
UNSAFE
Consuming alcohol while taking CX 5 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
CX 5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
CX 5 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
CX 5 Tablet may cause side effects which could affect your ability to drive.
CX 5 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
SAFE IF PRESCRIBED
CX 5 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of CX 5 Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
CX 5 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of CX 5 Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
CX 5 Tablet
₹3.17/Tablet
Wokexy FD Tablet
Wockhardt Ltd
₹1.97/Tablet
save 38%
Wokex 4 Plus Tablet
Wockhardt Ltd
₹5/Tablet
58% costlier

Patient Concerns

arrow
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
arrow
Do you have any questions related to CX 5 Tablet ?

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Rifampin, isoniazid and pyrazinamide. Bridgewater, New Jersey: Sanofi-Aventis; 2010. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Isoniazid + rifampicin + pyrazinamide. Guildford Surrey: Aventis Pharma Limited; 1984 [revised 12 Mar. 2019]. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 10 Apr. 2019] (online) Available from:External Link
  4. MedlinePlus. Pyridoxine. [Accessed 10 Apr. 2019] (online) Available from:External Link
  5. ScienceDirect. Pyridoxine. [Accessed 10 Apr. 2019] (online) Available from:External Link
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