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Progesterone Topical(8%)

food interaction for CRINONE(MERCK)

alcohol interaction for CRINONE(MERCK)

pregnancy interaction for CRINONE(MERCK)

lactation interaction for CRINONE(MERCK)

medicine interaction for CRINONE(MERCK)

No interaction found
No interaction found
Crinone 8% aplicap is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Crinone 8% aplicap is probably safe to use during breastfeeding. Please consult your doctor.
No interaction found


Progesterone Topical(8%)


Crinone 8% aplicap is used in female infertility

How it works

Progesterone belongs to a class of medications called as progestins (female hormones). It works by maintaining the progesterone levels in the body.

Common side effects

Adrenal insufficiency, Rash, Vaginal discharge, Headache, Dizziness, Back pain, Increased appetite, Decreased libido, Pain in extremity, Abdominal distension, Cushing syndrome, Sleepiness, Vomiting, Nausea, Edema, Abdominal pain, Lower abdominal pain, Breast pain, Hair loss, Fatigue, Acne, Hot flushes, Thrombophlebitis, Diarrhoea, Irregular menstrual cycle, Cushingoid syndrome, Increased blood pressure, Depression, Mood changes, Nervousness, Constipation, Increased glucose level in blood, Breathing difficulty


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Expert advice FOR CRINONE(MERCK)

  • Tell your doctor if you experience any unexpected bleeding. 
  • Tell your doctor if you have any conditions like recurrent fits, migraine, asthma, and heart or kidney dysfunction, as progesterone causes fluid retention and may worsen these conditions.
  • Do not use progesterone vaginal preparation simultaneously with any other vaginal therapy.
  • Exercise caution if you are suffering from abnormal glucose tolerance as progesterone might interfere in glucose metabolism.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
  • Do not use if you are allergic to progesterone or any of its ingredients.
  • Do not use if you have undiagnosed vaginal bleeding, blood clot in veins (thrombophlebitis) or those who have severe liver damage.
  • Do not use if you are suffering from or with history of any bleeding disorder (active deep vein thrombosis, pulmonary embolism).
  • Do not use if you have progesterone sensitive tumors.

Frequently asked questions FOR CRINONE(MERCK)

Progesterone Topical


Is progesterone a steroid?
Progesterone is a steroidal hormone naturally produced by the body and essential for the maintenance of a healthy uterus


Is estrogen and progesterone the same?
No. Estrogen and progesterone are two different steroidal hormones that work together for the development and maintenance of the female reproductive system


Is progesterone an androgen / diuretic / probiotic?
Progesterone belongs to a class of medications called as progestins (female hormones) and is different from androgens (predominantly male hormones). It is not a diuretic or probiotic

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Is utrogestan bioidentical/ natural progesterone / containing HCG?
Yes. Utrogestan is a trade name for hormone progesterone. It is structurally and functionally identical to the progesterone hormone naturally produced by the body and therefore bioidentical. It is sometimes referred to as natural progesterone, although it is synthesized in laboratories. It does not contain human chorionic gonadotropin (HCG) hormone


Is utrogestan same as cycloset?
No. Utrogestan and cycloset contain different active drugs. Utrogestan is a trade name for hormone progesterone. Cycloset is a trade name for active drug bromocriptine


Does progesterone/susten/susten400/susten100/utrogestan delay or stop period?
Susten and utrogestan are trade names for hormone progesterone. Progesterone can delay or stop periods for as long as it is taken. Your periods will return within a few days of stopping


Does progesterone increase breast size / cause acne/ sleepiness?
Progesterone has a side effect of causing breast tenderness, discomfort and increase in breast size. Acne is also a common side effect of taking progesterone. You may experience sleepiness and dizziness for few hours after taking progesterone


Can I take progesterone without a uterus?
Progesterone is not needed in women without a uterus or those who have undergone hysterectomy (surgery to remove the uterus)


Can I take progesterone with levothyroxine/synthroid/ tamoxifen/clomid?
There are no known drug interactions between progesterone when taken with synthroid (active drug- levothyroxine) or tamoxifen or clomid (active drug- clomiphene). However, inform your doctor about all medications currently taken before starting and while on progesterone


Can I just take progesterone without estrogen?
Yes. Your doctor may prescribe medicines that contain only progesterone.


Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)