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Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Cosklot Plus 250 mg/250 mg Tablet

Prescription Required
Storage
Store at room temperature (10-30°C)

Introduction

Cosklot Plus 250 mg/250 mg Tablet is a combination medicine used in the treatment of bleeding. It works by preventing the breakdown of blood clots and controls excessive bleeding. It also increases the ability of platelets to stick together and form blood clots.

You can take Cosklot Plus 250 mg/250 mg Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor.  Take this medicine in the dose and duration advised by the doctor and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.

The most common side effects of this medicine include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle or joint) pain. It may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods.

Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine.

Uses of Cosklot Plus Tablet

Side effects of Cosklot Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cosklot Plus

  • Nausea
  • Stomach pain
  • Diarrhea
  • Headache
  • Nasal congestion (stuffy nose)
  • Sinus pain
  • Sinus inflammation
  • Rash
  • Tiredness
  • Musculoskeletal (bone, muscle or joint) pain
  • Anemia (low number of red blood cells)

How to use Cosklot Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cosklot Plus 250 mg/250 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Cosklot Plus Tablet works

Cosklot Plus 250 mg/250 mg Tablet is a combination of two medicines: Tranexamic Acid and Ethamsylate. Tranexamic Acid is an antifibrinolytic. It works by preventing the breakdown of blood clots and controls excessive bleeding. Ethamsylate is a hemostatic. It works by increasing the ability of platelets to stick together and form blood clots. It also helps control bleeding from tiny blood vessels (capillaries).

Safety Advice

Alcohol
UNSAFE
Cosklot Plus 250 mg/250 mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Cosklot Plus 250 mg/250 mg Tablet during pregnancy is not available. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Cosklot Plus 250 mg/250 mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Cosklot Plus 250 mg/250 mg Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Cosklot Plus 250 mg/250 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Cosklot Plus 250 mg/250 mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Cosklot Plus 250 mg/250 mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Cosklot Plus 250 mg/250 mg Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Fact Box

Habit Forming
No
Therapeutic Class
BLOOD RELATED

Patient Concerns

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Hello, I am taking encorate chrono 500(2). Which tablet shall I take when I feel headache. It would be great if you could give me a natural way to solve the problem.
Dr. Vikas Sharma
Neurology
Napra 250 mg dos
Prefer tablets for the headache
Dr. Vikas Sharma
Neurology
Napra 250 mg so s
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Do you have any questions related to Cosklot Plus 250 mg/250 mg Tablet ?

User Feedback


FAQs

Q. Can the use of Cosklot Plus 250 mg/250 mg Tablet cause diarrhea?

Yes, the use of Cosklot Plus 250 mg/250 mg Tablet can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists. Do not take any other medicine without consulting a doctor.

Q. Can I use oral contraceptives while using Cosklot Plus 250 mg/250 mg Tablet?

No, do not use oral contraceptives while using Cosklot Plus 250 mg/250 mg Tablet. Use of oral contraceptives along with this medicine increases the chance of serious complications.

Q. Will a higher than the recommended dose of Cosklot Plus 250 mg/250 mg Tablet be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.

Q. What are the instructions for storage and disposal of Cosklot Plus 250 mg/250 mg Tablet?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Tranexamic acid. Camberley, Surrey: Sandoz Limited; 2003 [revised 29 Aug. 2017]. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Garay PR, Chiavaroli C, Hannaert P. Therapeutic Efficacy and Mechanism of Action of Ethamsylate, a Long-Standing Hemostatic Agent. Am J Ther. 2006;13(3):236-47. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. Medscape. Tranexamic acid. [Accessed 10 Apr. 2019] (online) Available from:External Link
  4. Negrete R, Molina M, Gutierrez-Aceves J. Preoperative administration of ethamsylate: reduces blood loss associated with percutaneous nepholithotomy? A prospective randomized study. J Urol. 2009;181(4S):625. [Accessed 10 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

64, Dodda Banaswadi Main Rd, Annaiah Reddy Layout, Banswadi, Bengaluru, Karnataka 560043
Expires on or after: January, 2021

A licensed vendor partner from your nearest location will deliver Cosklot Plus 250 mg/250 mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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