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Comvac 4 HB Injection


Product introduction

Comvac 4 HB Injection is a combination medicine used to prevent diphtheria, tetanus, pertussis and chronic hepatitis B virus (HBV) infection. It helps in developing immunity by initiating a mild infection. It helps the immune system to produce antibodies (proteins) to protect against any future infections.

Comvac 4 HB Injection should be injected by a doctor or healthcare professional. It is given via muscle in the anterolateral region of the thigh of infants and young children.  You should not take it if you have any known allergy from this injection.  Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.

The most common side effects include redness at the injection site, tenderness, irritability, vomiting, loss of appetite and fever. If any of these side effects or any other symptoms which you think are because of this medicine persist for a longer duration, please inform your doctor.


Benefits of Comvac 4 HB Injection

In Prevention of Chronic hepatitis B virus (HBV) infection

Hepatitis B is an infection of the liver caused by the Hepatitis B virus (HBV). When the infection moves into a long-lasting stage, it is called chronic hepatitis B virus infection. It can spread from person to person through blood, semen or other body fluids. Hepatitis B can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. Comvac 4 HB Injection is given to prevent hepatitis B infection. It is recommended for all infants and children of 6 weeks through 6 years of age. Hoever, it is advisable to consult your doctor for complete information regarding vaccination schedules.

In Prevention of Tetanus

Tetanus is a serious bacterial infection that affects the nervous system and causes muscles throughout the body to become stiff and tighten. Comvac 4 HB Injection helps prevent tetanus infection. It helps the immune system to produce antibodies to fight against tetanus infection. However, it does not provide lifelong protection. Children need to get a booster shot at 11 or 12 years of age. Adults need a booster shot every 10 years after that. It is advisable to consult your doctor for complete information regarding vaccination schedules.

In Prevention of Pertussis

Pertussis (often called whooping cough) is an infection of the airways that can occur at any age but mostly affects infants and young children. The infection causes uncontrollable coughing that can make it difficult to breathe. Comvac 4 HB Injection gives protection from pertussis. Infants and children need a dose of the vaccine starting at 2 months through 6 years. However, it is advisable to consult your doctor for complete information regarding vaccination schedules.

In Prevention of Diphtheria

Diphtheria is a bacterial infection that causes pain and swelling in the throat. This might cause difficulty in breathing. It might also damage the heart, kidneys and nerves. Comvac 4 HB Injection gives protection against diphtheria. It is recommended to get your child vaccinated against diphtheria starting at 6 weeks through 6 years. It is advisable to consult your doctor for complete information regarding vaccination schedules.

Side effects of Comvac 4 HB Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Comvac 4 HB

  • Injection site reactions (pain, swelling, redness)
  • Headache
  • Body ache
  • Muscle weakness
  • Tiredness
  • Joint pain
  • Feeling of discomfort

How to use Comvac 4 HB Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Comvac 4 HB Injection works

Comvac 4 HB Injection is a combination of four medicines. Diphtheria Toxoid, Tetanus Toxoid, Pertussis Toxoid, and Hepatitis B Vaccine (rDNA) are vaccines (inactivated microorganisms) that are formulated together to develop immunity by initiating a mild infection. This type of infection does not cause illness but stimulates the body's immune system to produce antibodies (proteins) to protect against any future infections. Aluminium Hydroxide is an adjuvant that helps to potentiate the action of the vaccine in the body by increasing its uptake. This is how it works to prevent various viral and bacterial infections.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Comvac 4 HB Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Comvac 4 HB Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Comvac 4 HB Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Comvac 4 HB Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Comvac 4 HB Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Comvac 4 HB Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Comvac 4 HB Injection helps to protect your child against diphtheria, tetanus, pertussis (whooping cough), and Hepatitis caused by Hepatitis-B virus.
  • Comvac 4 HB Injection should not be given to infants or children with fever or other evidence of acute illness or infection.
  • It is important to tell your doctor, if there is a personal or family history of central nervous system  disease or convulsions.
  • Comvac 4 HB Injection should not be given to children over six years of age or to adults.
  • Please tell your doctor if your child is taking or has recently taken any other medicines, including medicines obtained without a prescription.

Fact Box

Habit Forming
No
Therapeutic Class
VACCINES

Patient concerns

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Which types of vaccinations are mandatory for a child Which vaccinations are important for a child.
Dr. Gopal Bansilal Samdani
Paediatrics
Diphtheria/Tetanus/Pertussis (DTaP) -- Five-Dose Series. 2-4 months: Hepatitis A (Hep A) -- Two-Dose Series. 12-23 months: Hepatitis B (Hep B) Birth: H. influenzae type b (Hib) -- Three-Dose Series. 2-4 months: Influenza. Measles/Mumps/Rubella (MMR) -- Two-Dose Series. Pneumococcal (PCV) Chickenpox (Varicella)
Is Pentaxim injection is available and if not can we give any alternative ? Pls suggest.
Dr. Pranav Gupta
Paediatrics
Pentaxim has been withdrawn. However, you could still find some old stock. Alternatives are any DTwP vaccines. Easy 4, Comvac 4, Quadrovax, etc. A shot of IPV will be needed with each one of them
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. COMVAC 4-Hb. Bharat Biotech. [Accessed 12 Sep. 2019] (online) Available from:External Link
  2. Diphtheria, Tetanus, Pertussis Whole Cell and Recombinant Hepatitis B Vaccines [Package Insert]. Shameerpet, Hyderabad: Bharat Biotech International Limited. [Accessed 19 Oct. 2023] (online) Available from: External Link

Marketer details

Name: Bharat Biotech
Address: Genome Valley Shameerpet, Hyderabad – 500 078 Telagana INDIA
Country of origin: India

121
Inclusive of all taxes
MRP125  3% OFF
1.0 ml in 1 vial
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