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Last updated on:
16 Jul 2019 | 05:04 PM (IST)
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Combutol 200 Tablet

Prescription Required
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Overview

Uses of Combutol Tablet

Combutol Tablet side effects

Common
  • Visual impairment
  • Color blindness

How to use Combutol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combutol 200 Tablet is to be taken with food.

How Combutol Tablet works

Combutol 200 Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Combutol Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Combutol 200 Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Combutol 200 Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Combutol 200 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Combutol 200 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combutol 200 Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Combutol 200 Tablet should be used with caution in patients with liver disease. Dose adjustment of Combutol 200 Tablet may be needed. Please consult your doctor.

What if you miss a dose of Combutol Tablet?

If you miss a dose of Combutol 200 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Combutol 200 Tablet
₹1/Tablet
Themibutol 200mg Tablet
Themis Medicare Ltd
₹1.08/Tablet
8% costlier
ALBUTOL 200MG TABLET
Alkem Laboratories Ltd
₹0.39/Tablet
save 61%
₹0.94/Tablet
save 6%
₹0.73/Tablet
save 27%
₹0.83/Tablet
save 17%

Expert Advice

  • Combutol 200 Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
  • It has to be taken for several months in order for it work properly (usually 6 months).
  • Take it with food to avoid stomach upset.
  • It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
  • Avoid consuming alcohol while taking this medication.
  • Do not stop taking Combutol 200 Tablet even if you start to feel better. Stopping early can  can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Interaction with Drugs

Taking Combutol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Magflux, Magasip
MINOR
Brand(s): Sodamax, Sobinix, Sobimed
MINOR

Patient Concerns

Questions Related to Combutol

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Sgot 42.8, sgpt 47.10. Taking recin 300, combutol 800, cifrocin 5 mg
Dr. Sunil Sekhri
Diabetes Specialist
Since you are taking medication of tuberculosis increase in Liver enzymes does happen. If you develop jaundice then change of medications might be required
Sir,I'm a tb patient ,doctor give me medicine,but i don't know how i take this medicine ,before meal or after meal please help meThis is my medicineSolonex 300 mg R cin 600mg Pyzina 1500mg combutol 1000mg Pyridoxin 40mg
Dr. Pushkar Mani
Diabetes Specialist
That u have to ask ur and also u visit dots centre for tuberculosis tratment
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Do you have any questions related to Combutol 200 Tablet?

User Feedback


FAQs

Q. My child vomited after taking Combutol. What should be done?

If your child vomited within 30 minutes of taking Combutol, give the same dose again. If vomiting occurred 30 minutes after taking Combutol, you need not repeat the dose. If your child vomits again after taking Combutol, consult your doctor.

Q. For how long does Combutol stay in your system?

Combutol stays for about 24 hours in your system. This duration varies from person to person and maybe different for patients with kidney problems.

Q. Will Combutol work if I have developed tuberculosis for the second time?

Yes, it will work if you had taken proper treatment and got cured when you developed tuberculosis for the first time. If you have any doubt, ask your doctor.

Q. Is it necessary to take so many TB drugs simultaneously? Is there no single medicine which can provide a cure for tuberculosis?

Yes, it is important that you take all the prescribed TB drugs together for the recommended duration, else you will not be cured. A single drug is not prescribed to treat TB because it may increase the risk of developing multi-drug resistant tuberculosis, which is very difficult to treat.

Q. What is drug resistance? Can I become resistant to Combutol?

Sometimes it happens that bacteria gets modified in your body and stops reacting to the medicine. As a result, the medicine stops working. This is called drug resistance. Drug resistance is uncommon if Combutol is used in combination with other TB drugs.

Q. Can Combutol treatment be taken for more than two months?

Yes, Combutol can be continued for more than 2 months, depending on your condition and as per your doctor’s advice. If after 2 months, your investigations show that the TB bacteria are still active, you may have to take Combutol for 1 more month. In case you are resistant to other TB drugs, you may have to take Combutol and other TB drugs (for which you are not drug resistant) for longer than 2 months.

Q. What are the warning signals which should prompt me to stop taking Combutol?

You should consult your doctor and consider stopping the medicine immediately if you develop any vision problems like blurred vision, color blindness or any kidney problems like decreased amount of urine and swelling of your legs and feet. You may even develop liver troubles like nausea, vomiting and yellowish color of skin and eyes. Beware of all these symptoms and consult your doctor immediately.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1558-559.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 826-27.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 506.
  4. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 01 Apr. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:External Link
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