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MRP: Rs. 43 for 1 strip(s) (10 tablets each)
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Composition for COLIBEST

Drotaverine(40 mg),Nimesulide(100 mg)

food interaction for COLIBEST

alcohol interaction for COLIBEST

pregnancy interaction for COLIBEST

lactation interaction for COLIBEST

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Colibest 40mg/100mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Drotaverine(40 mg)


Drotaverine is used to relieve spasm of smooth muscles in organs such as stomach and heart. It is used in the treatment of pain due to some condition such as ulcers of the intestine, irritable bowel syndrome, various diseases of intestines, pain due to gall stones and stones in the kidneys, pain due to various diseases of the liver and gall bladder, Drotaverine is also to treat certain types of headaches, for painful periods, and to relieve cervical spasm during labor.

How it works

Drotaverine belongs to a group of medicines called antispasmodics. Drotaverine decreases the tone of smooth muscles, reduces intestinal peristalsis and dilates blood vessels. It thereby acts as a direct relaxant of the smooth muscles of the gut and relieves painful contractions called as spasms.

Common side effects

Dizziness, Decreased blood pressure, Nausea, Vomiting
Nimesulide(100 mg)


Nimesulide is used to treat acute pain, osteoarthritis (pain and swelling of joints due to degeneration) and pain during periods.

How it works

Nimesulide belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs) which works by blocking the production of prostaglandins (a chemical associated with pain) thereby relieving pain and inflammation.

Common side effects

Nausea, Rash, Abnormal blood cell count, Anemia, Constipation, Diarrhoea, Dizziness, Shortness of breath, Gastritis, Hypersensitivity reaction, Increased blood pressure, Swelling, Increased sweating, Itching, Liver enzyme increased, Vomiting


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Expert advice for COLIBEST

  • Take drotaverine tablets 20 minutes before a meal to relieve or reduce post meal symptoms.
  • Consult your doctor before you start drotaverine if you are pregnant or plan to become pregnant.
  • Stop taking drotaverine and consult a doctor, if experience severe allergic reactions.
  • Due to possible side effects such as dizziness and vertigo resulting from hypotension, you should avoid driving or using machines.

Frequently asked questions for COLIBEST


Q.What is drotaverine used for/ What does drotaverine treat?
Drotaverine is used to treat spasm of smooth muscles in organs such as stomach and heart. Drotaverine is mainly used to relieve painful spasms associated with chronic gastroduodenitis (inflammation of the stomach and the duodenum of the small intestine), gastric and duodenal ulcers, irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen) and many more conditions of the stomach and intestine that are associated with painful spasm. It may also be used to relieve pain during menstruation (dysmenorrhea).


Q. Is Nimesulide an antibiotic?
No, Nimesulide is non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) which relieves acute pain in conditions like joint pain and period pain. However, it may be used with antibiotics to relieve pain associated with certain infections.
Q. Can I take Nimesulide with paracetamol or ibuprofen?
Nimesulide, paracetamol and ibuprofen are non-steroidal anti-inflammatory drugs (NSAIDs; pain-relieving drugs). Taking two NSAID drugs together is not advisable as it may increase the potential for gastric ulceration and bleeding.
Q. Does Nimesulide contain aspirin or sulphur?
No. Nimesulide is a non-steroidal anti-inflammatory drug (NSAIDs; pain-relieving drug) doesn’t contain aspirin or sulphur.
Q. Is Nimesulide safe?
Nimesulide is safe at prescribed dose and duration as advised by your doctor.


Content on this page was last updated on 04 July, 2014, by Dr. Varun Gupta (MD Pharmacology)