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Composition for CLOPINATE M


food interaction for CLOPINATE M

alcohol interaction for CLOPINATE M

pregnancy interaction for CLOPINATE M

lactation interaction for CLOPINATE M

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Clopinate m cream may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Clopinate m cream is probably safe to use during breastfeeding. Please consult your doctor.




Clobetasol is used to treat itching, redness, dryness, swelling, and discomfort of various scalp and skin conditions, including immune-mediated skin disease with red scaly patches (psoriasis).

How it works

Clobetasol is a highly potent topical corticosteroid. It reduces the actions of chemicals in the body that cause inflammation.

Common side effects

Itchy bump, Application site irritation, Burning sensation, Itching


Miconazole is an imidazole (organic compound) antifungal agent used to treat fungal and associated bacterial super infections of the skin and nails Miconazole is also used for oral treatment and prevention of fungal infections of the mouth, throat and food pipe Miconazole is effectively used in vulvovaginal (vagina and external genital organs) candidiasis (thrush) and other yeast infection of the vagina. Further, Miconazole is also prescribed for napkin rash and inflammation of the folds of tissue surrounding the nails of toes or fingers (paronychia). 

How it works

Miconazole acts mainly by preventing the growth of fungi. It interacts with chemicals (cytochrome P-450) inside the fungus and prevents the synthesis of an essential component of fungal cell membrane (ergosterol); this results in increased cellular permeability causing leakage of cellular contents from fungal cell, ultimately preventing fungal growth. Miconazole possesses antifungal activity against dermatophytes and yeasts as well as antibacterial activity against certain gram-positive bacilli and cocci.

Common side effects

Abdominal pain, Burning sensation, Itching, Vaginal discharge, Vaginal irritation, Vaginal swelling, Fever


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Expert advice for CLOPINATE M

Always clean the skin before a fresh dressing is put on since the germs can cause infections under warm and moist conditions under dressings.
Make sure you wash your hands after use or wear disposable plastic gloves while applying the cream on someone. Cream should be used on skin externally only.
Treatment beyond 2- 4 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week.
If your skin problem does not improve in 2 to 4 weeks, talk to your doctor. Do not use in conditions such as
  • Acne
  • Fungal skin infections, eg. athlete's foot, ringworm, candida skin infections.
  • Severe flushing of skin on and around your nose (rosacea).
  • Spotty red rash around your mouth (perioral dermatitis).
  • Infected skin (unless the infection is being treated with an anti-infective medicine at the same time).
  • Itchy skin around the genitals or back passage.
  • Itchy skin which is not inflamed.
  • Nappy rash
  • Widespread plaque psoriasis.

Frequently asked questions for CLOPINATE M


Q. Is clobetasol propionate a steroid/ an antifungal/ OTC?
Clobetasol (also available as Cosvate cream, Cosvate G) is a potent topical corticosteroid used for the treatment of itching, redness, dryness, inflammation, and discomfort of various scalp and skin conditions. It is not an antifungal. It is available only by prescription given by your doctor.
Q. Is clobetasol propionate used for hair loss/ does clobetasol help hair growth?
Clobetasol is used for discomfort in various scalp and skin conditions; however not used for treatment of hair loss or hair growth. Always consult your doctor regarding its use.
Q. Does clobetasol propionate cause hair loss / thinning of skin?
Long-term use of steroids may damage your hair or skin. Always follow the advice of your doctor regarding its use.
Q. Is clobetasol propionate good for acne/ athlete's foot/ ringworm?
Clobetasol should not be used for conditions like acne, athlete’s foot or ringworm. Always consult your doctor regarding its use.


Q. Can miconazole/ Monistat be used for conditions for BV (bacterial vaginosis), ring worms, and urinary tract infections?
Yes, miconazole can be used for BV (bacterial vaginosis). It is used for treatment and prevention of fungal infections of the oral cavity, ring worms and superinfections due to gram-positive bacteria. Miconazole can be taken in rare fungal infections of the urinary tract.
Q. Does miconazole cause burning sensation? 
Yes, burning sensation on the skin and vaginal burning are common side effects of miconazole.
Q. Does miconazole cause dry skin? 
No, miconazole is not known to have the side effect to cause drying of skin. 
Q. Is miconazole safe for babies?
Yes, miconazole is safe for babies. It may be used in nappy rashes and oral fungal infections as advised by your doctor.
Q. Is miconazole a steroid?
No, miconazole is not a steroid. It is an imidazole (organic compound) and belongs to class of antifungal agents.
Q. Is miconazole same as ketoconazole?
Both miconazole and ketoconazole are antifungal medicines. However, they are prescribed for different type of fungal infections.
Q. Can I take miconazole with fluconazole? 
Taking two antifungal agents may have additive effect and have pronounced side effects. Patients should follow advice of the doctor regarding its use.
Q. Does miconazole work for yeast infections?
Yes, miconazole works for oral and vaginal yeast infections.
Q. Does miconazole expire?
Yes, antifungals like miconazole have an expiry date. Read instruction on the pack for the date of expiry.
Q. Is miconazole an OTC (over the counter)?
No, miconazole cannot be bought over the counter. It needs prescription of a qualified doctor.


Content on this page was last updated on 01 May, 2015, by Dr. Varun Gupta (MD Pharmacology)