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Composition for CEFTRIMAX

Ceftriaxone(250 mg),Sulbactam(125 mg)

food interaction for CEFTRIMAX

alcohol interaction for CEFTRIMAX

pregnancy interaction for CEFTRIMAX

lactation interaction for CEFTRIMAX

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Ceftrimax 250mg/125mg injection is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Ceftriaxone(250 mg)


Ceftriaxone is used to treat bacterial infections of the brain respiratory tract ear abdomen abdominal wall, urinary tract and kidney, bones, joints, and skin or soft tissues. It is also used in the management of fever with low white blood cells (neutropenia), surgical site infections, joint pain caused by parasite ticks (Lyme disease), typhoid, paratyphoid and sexually transmitted infections (gonorrhea, syphilis).

How it works

Ceftriaxone belongs to group of medicines called cephalosporin antibiotics. It kills the bacteria by interrupting the bacterial cell wall (outer coating of bacteria) formation. As a result, the bacterial cell wall is weakened and ruptured, thereby killing the bacteria.

Common side effects

Vomiting, Nausea, Allergy, Flushing, Application site burning, Application site pain, Application site warmth, Chest pain, Dizziness, Diarrhoea, Skin rash, Fever, Headache, Heartburn, Black and bloody stools, Stomach cramp, Stomach pain, Bloating
Sulbactam(125 mg)


Sulbactam is used in combination with other antibiotics for treating certain bacterial infections. It is used to treat intraabdominal, gynecological, skin or soft tissue, and surgal infections, especially those developed in the hospital.

How it works

Sulbactam belongs to group of medicines called betalactamase Inhibitor with very weak action against bacteria.  Beta-lactamase inhibitors are available only in fixed combinations with specific penicillins (beta-lactam antibiotics) such as amoxicillin, ampicillin, piperacillin, and ticarcillin. It works by preventing destruction of beta-lactam antibiotics from chemicals released from bacteria and extends their spectrum of activity.

Common side effects

Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing


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Expert advice for CEFTRIMAX

  • It is given as a drip (intravenous infusion) or as an injection directly into a vein or into a muscle. It is made up by the doctor, or nurse using water for injections or a suitable infusion fluid.
  • Do not drive because you may feel sleepy or dizzy while being treated with ceftriaxone.
  • Tell your doctor if you are taking, have recently taken or might take any other medicines. This includes medicines you can obtain without a prescription. 
  • Do not start or continue the ceftriaxone and consult your doctor if you have a liver or   kidney disease.
  • Do not take this drug and consult your doctor  if you are pregnant or planning to become pregnant or breastfeeding.

Frequently asked questions for CEFTRIMAX


Q. Is ceftriaxone a form of penicillin drug?
No, ceftriaxone is not a penicillin drug.

Q. Is it bactericidal or bacteristatic?
 It is a cephalosporin antibiotic. It is bactericidal drug.
Q. Is ceftriaxone safe in liver disease?
Yes, ceftriaxone is safe in liver disease. Please consult your doctor for your medical condition before taking the drug.
Q. Is ceftriaxone compatible with potassium or potassium chloride?
Yes, ceftriaxone is compatible with potassium or potassium chloride when taken together.
Q.Is ceftriaxone the same as cephalexin, Monocef-o, Monocef 200, Monocef tablet, Cefakind, or Cefakind 250?
No, all are different cephalosporin antibiotics. Monocef-o, Monocef 200, or Monocef tablet contain cefpodoxmine, and Cefakind, or Cefakind 250 contain cefuroxime.
Q. What organisms does ceftriaxone cover?
Ceftriaxone is active against pseudomonas, staphylococcus, and klebsiella bacteria. It has no activity against chlamydia, methicillin-resistant Staphylococcus aureus (mrsa), and mycoplasma.


Q. Is sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor.
Q. What is sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins.
Q. Is sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.


Content on this page was last updated on 07 July, 2015, by Dr. Varun Gupta (MD Pharmacology)