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Composition for CEFRINE

Cefdinir(125 mg),Lactobacillus(20 mg)

food interaction for CEFRINE

alcohol interaction for CEFRINE

pregnancy interaction for CEFRINE

lactation interaction for CEFRINE

There is no data available. Please consult doctor before consuming the drug.
Cefrine 125mg/20mg tablet dt may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Human and animal studies are not available. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Cefdinir(125 mg)


Cefdinir is used to treat respiratory tract infections such as inflammation of tonsils (tonsillitis), throat (pharyngitis) or air passages (bronchitis), lung (pneumonia), sinus infection (sinusitis), ear infections (otitis media), and skin infections.

How it works

Cefdinir belongs to group of medicines called cephalosporin antibiotics. It kills the bacteria by interrupting the bacterial cell wall (outer coating of bacteria) formation. As a result, the bacterial cell wall is weakened and ruptured, thereby killing the bacteria.

Common side effects

Diarrhoea, Dizziness, Fatigue, Headache, Loss of appetite, Nausea, Stomach upset, Vomiting
Lactobacillus(20 mg)


Lactobacillus (Lactobacillus acidophilus, L. bulgaricus, L.casei, L. rhamnosus.)  is used in the following conditions:
  • Prevention and treatment of diarrhea caused by rotavirus infection in children, traveler’s diarrhea in adults and diarrhea associated with hospitalization, antibiotic treatments and cancer chemotherapy.
  • Irritable bowel syndrome, and ulcerative colitis.
  • As a combination with other medications in the treatment of Helicobacter pylori infections that cause stomach ulcers.
  • Infections of vagina caused by bacteria (bacterial vaginosis) or yeast.
  • Prevention and treatment of skin diseases in infants and children who are allergic to cow’s milk.
  • Prevention of lung infections in children aged between 1 to 6 years.
  • Treatment of high cholesterol, sugar intolerance.
  • Boost to immune system.

How it works

Lactobacillus is a family of useful bacteria found naturally in the mouth, intestine and vagina. Products containing lactobacillus are used as ‘probiotics’ that help restore the levels of these good bacteria. It provides health benefits by assisting break down of food and absorption of nutrients; also stimulating the body’s immune response. It also produces substances that suppress or kill harmful bacteria and creates an unfavorable environment for the growth of disease causing bacteria.

Common side effects

Flatulence, Abdominal bloating


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Expert advice for CEFRINE

  • Do not start or continue the cefdinir and consult your doctor if you have inflammation of large intestine (colitis) or kidney disease, or if you are pregnant, planning to become pregnant or breast feeding.
  • Take cefdinir 2 hours before or 2 hours after antacids or iron containing products or medicines.
  • Do not drive or operate any machinery because you may feel sleepy or dizzy while being treated with cefdinir. These effects may be worsen with alcohol, so avoid taking cefdinir and alcohol together.
  • Caution should be taken when giving cefdinir to the children younger than 6 months old or to patients with diabetes as it may affect the results for urine glucose or ketone tests.
  • Inform your doctor if you are taking BCG or live typhoid vaccine during cefdinir treatment, as cefdinir will decrease the effectiveness of these vaccines.

Frequently asked questions for CEFRINE


Q. Is cefdinir a penicillin or sulfa drug?
No, cefdinir is not a penicillin or sulfa drug. It is a cephalosporin antibiotic.
Q. Does cefdinir affect birth control?
Cefdinir can reduce effectiveness of birth control pills. Please consult your doctor before taking the drug.
Q. Does cefdinir cause constipation, red stool, or diarrhea?
Cefdinir may cause diarrhea or red stool but it is not known to cause constipation.
Q. Can I take cefdinir with Allegra (fexofenadine hydrochloride), Benadryl (diphenhydramine), Mucinex (guaifenesin), Nyquil (acetaminophen, dextromethorphan, doxylamine, and pseudoephedrine), Sudafed (dextromethorphan and phenylephrine), Tylenol (acetaminophen), hydrocodone, or ibuprofen?
Cefdinir is not reported to interact with Allegra, Benadryl, Nyquil, Sudafed, Tylenol, hydrocodone, or ibuprofen. Please follow the advice of the doctor regarding their simultaneous use.
Q. Does cefdinir treat strep or sore throat, urinary tract infection (UTI), bladder infection, or tooth infection?
Yes, you can take cefdinir in strep or sore throat; UTI, or bladder infection. Please consult your doctor for your medical condition before taking the drug.
Q. Is cefdinir gluten free?
Yes. Cefdinir is gluten free. However, please refer to package insert of the prescribed brand before use.
Q. Is cefdinir generic?
Yes, cefdinir is available as generic drug.
Q. Does cefdinir liquid need to be refrigerated?
Cefdinir needs to be stored at 15° to 30°C. It should not be frozen.
Q. Is cefdinir safe?
Cefdinir is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.


Q. Is lactobacillus/Lactobacillus acidophilus vegan/ dairy free?
Some products of lactobacillus/Lactobacillus acidophilus contain dairy products and may not be suitable for vegans. Please refer to package insert of the prescribed brand before use.
Q. Is lactobacillus good or bad/pathogenic?
Lactobacillus is a group of ‘good’ bacteria that provide several health benefits. It is not among the disease causing (pathogenic) bacteria.
Q. Is lactobacillus and Lactobacillus acidophilus same?
Lactobacillus acidophilus is a species of lactobacillus bacteria. Their role as a probiotic in the maintenance of good health is the same.
Q. Is lactobacillus gram negative?
Lactobacillus is a gram positive bacteria.
Q. Is lactobacillus motile?
Certain species or strains of lactobacillus are motile.
Q. Is Lactobacillus acidophilus good for yeast infections/can I take Lactobacillus acidophilus for yeast infections?
Yes. Lactobacillus has been regarded beneficial in the treatment of yeast infections of the vagina.
Q. Can I take Lactobacillus acidophilus for bad breath?
The benefits of Lactobacillus acidophilus in improving bad breath have not been established.
Q. How long can I take acidophilus for?
The duration of treatment with lactobacillus/Lactobacillus acidophilus depends upon the condition being treated and is decided by the doctor.
Q. Can you take lactobacillus with antibiotics?
Concomitant use of lactobacillus with antibiotics can lower its effectiveness. Products containing lactobacillus should be taken at least 2 hours before or after antibiotics.
Q. Does lactobacillus cause/produce gas?
Yes. Gas and bloating is a side effect of lactobacillus. In most cases these mild side effects subside with continued use.
Q. Does lactobacillus cause UTI?
Lactobacillus is not known to cause urinary tract infections (UTI).
Q. Does Lactobacillus casei contain casein?
Lactobacillus casei is one of the species of lactobacillus and is used a probiotic. Some products of lactobacillus contain dairy products and may contain casein. Please refer to package insert of the prescribed brand before use.
Q. Does lactobacillus create CO2/produce alcohol?
Yes. Lactobacillus may produce carbon dioxide gas and alcohol as a part of its normal cellular process (metabolism).
Q. Does Lactobacillus acidophilus need to be refrigerated?
Dairy based Lactobacillus acidophilus products may need refrigeration. Please refer to package insert of the prescribed brand for instructions.


Content on this page was last updated on 09 March, 2015, by Dr. Varun Gupta (MD Pharmacology)