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Ramipril(5 mg)


Ramipril is mainly used to control high blood pressure (hypertension). It is used to treat heart failure, to improve survival after heart attack and to prevent stroke. Ramipril is also used to treat various kidney diseases.

How it works

Ramipril belongs to a class of drugs called ACE inhibitors (angiotensin converting enzyme inhibitors), Ramipril inhibits the chemical ACE (angiotensin converting enzyme). As a result, there is relaxation of blood vessels leading to a fall in blood pressure which makes it easier for the heart to pump blood.

Common side effects

Common: Headaches, decrease in blood pressure, fainting, insufficient blood supply to the muscles of the heart causing a sensation of pressure, indigestion, inflammation of air passages, breathlessness, , abnormal blood counts, vomiting, disturbances in digestion, non-productive cough, muscle pain, rashes, inflammation of the air-cavities around nose, urge to vomit, abdominal discomfort, loose motions, inflammation of the gastrointestinal tract, or pain in chest, blood potassium, unusual tiredness, dizziness, chest pain, excessive fall in blood pressure with change of position, squeezing, involuntary contraction of muscle or group of muscles, muscle cramp/ sudden

Hydrochlorothiazide(12.5 mg)


Hydrochlorothiazide is used to treat high blood pressure (hypertension). It also treats fluid retention (edema) due to congestive heart failure or cirrhosis of liver or kidney disorder.

How it works

Hydrochlorothiazide belongs to class of medications called thiazide diuretics. It acts by eliminating the fluid and salts from the body. It works on the kidneys to produce more urine which removes extra water and certain salts from the body which in turn lowers blood pressure and swelling.

Common side effects

decrease in blood cell count, hypersensitivity reactions., kidney failure, Electrolyte imbalance, glucose, nausea, presence of glucose in urine, inflammation of the pancreas, vomiting, increase in cholesterol, kidney dysfunction, stomach irritation, constipation, diarrhea, dizziness, fever, or uric acid levels.severe skin allergies, muscle cramps, jaundice


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Expert advice

  • Do not take ramipril with any other product containing aliskiren if you are diabetic or have kidney problems.
  • Do not take ramipril if you have narrowing of one or both arteries that carry blood to kidneys causing reduced blood flow to the kidneys (bilateral renal artery stenosis or renal artery stenosis in a single functioning kidney), abnormally low or unstable blood pressure.
  • Do not consume if you are undergoing dialysis or any blood filtration technique as ramipril may cause sudden and severe reactions. 
  • Discontinue ramipril and consult your doctor if you suffer from cough or swelling of eyes and lips (angioedema).
  • Before taking ramipril, consult your doctor if you are suffering from severe increase in blood pressure, have worsening of symptoms of pre-existing heart failure (decompensated heart failure).

Frequently asked questions


Q. Is ramipril a diuretic?
No, ramipril is not a diuretic It belongs to a class of drugs called ACE inhibitors (angiotensin converting enzyme inhibitors), mainly used to reduce high blood pressure.

Q. Is ramipril safe?
Ramipril is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q. Is ramipril or cardace a calcium channel blocker/alpha blocker/ beta blocker?
No, ramipril or cardace is an ACE inhibitor and shows no known effects on calcium channels or alpha receptors or beta receptors.

Q. Is ramipril a nitrate or a statin?
Ramipril is neither a nitrate nor a statin. It is an ACE inhibitor used to treat high blood pressure.

Q. What are Cardace / Ramistar/Hopace used for?
Cardace, Ramistar, Hopace are all trade names for the active drug ramipril. Ramipril is an ACE inhibitor used to treat high blood pressure.

Q. Can I take ramipril with simvastatin/amlodipine/ Viagra/naproxen/prednisolone/ metformin/ Sudafed (pseudoephedrine-decongestant preparation)?
There are no known serious drug interactions between ramipril when taken with simvastatin/ amlodipine/ Viagra/naproxen/prednisolone/ metformin/Sudafed. However, consult your doctor about all medications currently taken before starting and while on ramipril.

Q. Can I take ramipril with ibuprofen?
Ibuprofen can be taken with ramipril, however, it is known that ibuprofen and other NSAIDs may reduce the antihypertensive effects of ramipril. Consult your doctor about any medications currently taken before starting and while on ramipril.

Q. Can I take ramipril with food or orange juice?
Ramipril can be taken before, with or after food or juice, because food intake does not modify its effects.

Q. Does ramipril cause coughing?
Yes, non-productive tickling cough, is one of the common side effects or ramipril.

Q. Does ramipril cause frequent urination?
No, ramipril has no known effect on increasing the frequency of urination. It may rarely increase the urine output but not affect the frequency of urination.

Q. Does ramipril cause itching?
Yes, ramipril may cause itching of skin. It is not very commonly observed.

Q. Does ramipril cause an increase in potassium levels in the blood?
Yes, increased potassium levels is one a common side effects of ramipril.

Q. Does ramipril cause depression?
Yes, ramipril may cause depression; however, it is not very commonly observed.

Q. Does ramipril thin the blood?
No. ramipril has no known effect on blood thinning.

Q. Is ramipril available in India?
Yes, ramipril is available in India with more than 100 brand names.


Q. Hydrochlorothiazide is a diuretic,which increases the excretion of urine?
Patients should follow the advice of the doctor regarding its use.

Q. Is hydrochlorothiazide a statin/ opiate?
No.It is the derivative of chlorothiazide.

Q. Is hydrochlorothiazide bad for your kidneys?
No.Hydrochlorthiazide is a safe drug at prescribed dose by your doctor. Consult your doctor if you have kidney disease and follow the advice of the doctor regarding its use.

Q. Can I take hydrochlorothiazide with lisinopril/ ibuprofen/ synthroid/ aspirin/ potassium/ phentermine/ losartan/ naproxen/ magnesium/ vitamins?
Taking other medicines may alter the effects of hydrochlorothiazide. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.

Q. Does hydrochlorothiazide cause diabetes/ erectile dysfunction/ weight loss/ gout/ constipation/tinnitus/ potassium loss?
Hydrochlorothiazide causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects.

Q. Does hydrochlorothiazide have sulfa in it?
Yes.Hydrochlorothiazide has sulfa and it is chemically known as 6-chloro- 3, 4-dihydro-2 H-1, 2, 4-benzothiadiazine-7-sulfonamide 1, 1-dioxide.

Q. Does hydrochlorothiazide clean your system?
No.Hydrochlorothiazide reduces extra fluid in the body.

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