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Composition for AZEFLO

Fluticasone(50 mcg),Azelastine(140 mcg)

food interaction for AZEFLO

alcohol interaction for AZEFLO

pregnancy interaction for AZEFLO

lactation interaction for AZEFLO

Avoid Azeflo 50 mcg/140 mcg spray with grapefruit juice.
Azeflo 50 mcg/140 mcg spray may cause excessive drowsiness and calmness with alcohol.
Azeflo 50 mcg/140 mcg spray may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Fluticasone(50 mcg)


Fluticasone is used to control symptoms of asthma, allergies of nose, throat or chest that cause symptoms of stuffy, runny or itchy nose, sneezing and watery, itchy or red eyes, skin problems like itchy rash (eczema), redness and itchiness (psoriasis), inflammation (dermatitis), prickly heat or insect bites in adults or dermatitis in children.

How it works

Fluticasone belongs to a class of drugs called glucocorticoids/steroids. It prevents the release of the substances in the body that cause inflammation and allergies.

Common side effects

Nausea, Nose bleed, Fever, Chest tightness, Cough, Headache, Hoarseness of voice, Nasal congestion, Sinus pain, Sneezing, Sore throat, Stomach upset, Vomiting, White spots in the mouth
Azelastine(140 mcg)


Azelastine is an antihistamine (antiallergic) medication used for the treatment of hay fever, and allergy symptoms including runny nose, sneezing, and itchy nose and eye allergies (allergic conjunctivitis). 

How it works

Azelastine belongs to the group of medicines called antihistamines. It acts by blocking a natural chemical (histamine) that is produced in the body during an allergic reaction.

Common side effects

Nausea, Pale red skin, Itchy rash, Cough, Drowsiness, Fatigue, Headache, Itching, Skin irritation, Tingling sensation, Nose bleed, Sneezing, Sore throat, Bitter taste

Common Dosage

Patients taking this medicines

  • 46%
    One Time A Day
  • 45%
    Two Times A Day
  • 7%
    Three Times A Day
  • 2%
    Four Times A Day


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Expert advice for AZEFLO

  • Do not use the medicine (inhaler or spray): If you are allergic to it or to any other content in the medicine. If you are pregnant, planning to become pregnant or breast-feeding a baby.
  • Inform your doctor before using the medicine if you have tuberculosis, other chest or lung infection, breathing problem, cold, liver disease or thin or brittle bones.
  • Do not use fluticasone inhalation to treat an asthma attack that has already begun.
  • Do not use fluticasone inhalation of you are allergic to milk proteins.
  • Do not use the fluticasone cream on areas where you have itchiness, redness, rashes, infection or acne on the skin.
  • Inform your doctor if you have breathing problems or tightness in the chest even after taking the medicine.

Frequently asked questions for AZEFLO


Q. Is fluticasone an antibiotic/steroid/anti-histaminic/anti-cholinergic drug?
Fluticasone is a steroid but not an antibiotic/anti-histaminic/anti-cholinerhic/decongestant drug. 
It is used to treat nasal congestion (decongestant) and other symptoms caused by allergies or conditions like asthma.

Q. Does it contain sulfa?
 It does not contain sulfa.
Q. Is fluticasone available over the counter?
No. Fluticasone is a prescription drug. It is not available over the counter.
Q. Is Fluticasone the same as Nasonex/Flonase?
Fluticasone is also available in the branded form as Flonase nasal spray. 

Q. Does it contain acetaminophen?
However, Nasonex consists of another drug called Mometasone also used for treating nasal allergies. Acetaaminofen is a different medication.
Q. What is used for?
Fluticasone (in the form of inhaler) is used to treat symptoms of asthma and nasal inflammation such as coughing, wheezing, blocked nose, runny nose.

Q. Is fluticasone used for cold?
 It is also used as topical cream to treat various skin allergies and infections. It is not used for common cold.
Q. Can I take fluticasone with Benadryl/Sudafed/Zyrtec/ Afrin/Allegra/Mucinex?
Yes. Fluticasone may be taken with Benadryl (diphenhydramine)/Sudafed (pseudoephedrine)/Zyrtec (cetrizine)/ Afrin (oxymetazoline)/Allegra (fexofenadine)/Mucinex (guaifenesin) if prescribed by your doctor.
Q. Does fluticasone propionate cause weight gain/drowsiness/ wakefulness?
Fluticasone may cause weight gain since it is a steroid drug. It may cause drowsiness or wakefulness. If you experience any such symptoms, please consult your doctor.
Q. Is fluticasone addictive?
No. Fluticasone is not an addictive or a controlled/banned substance.
Q. Dose fluticasone cause nose bleeds?
Yes. The most common and expected side-effect of fluticasone nasal spray/inhaler is nose bleeding. If your bleeding is more or does not stop, please consult your doctor.
Q. Can I take fluticasone if I have high blood pressure?
It is advisable to consult your doctor before taking fluticasone if you have high blood pressure.


Q. Is azelastine/Duonase/ a steroid/anticholinergic/corticosteroid/antihistamine/decongestant?
It is an antihistaminic drug.

Q. Is azelastine over the counter/OTC?
No, it is available with doctor’s prescription only.

Q. Is azelastine addictive?
No, it is not addictive. Patients should follow the advice of the doctor regarding its use.

Q. Is azelastine the same as Flonase?
No, azelastine is a different drug. Flonase contains the drug fluticasone.

Q. Can I take Benadryl/Zyrtec/Claritin with azelastine?
Taking other medicines may alter the effects of azelastine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.

Q. Does azelastine/azelastine Hcl work?
It works at the prescribed dose for suggested disease condition. Patients should follow the advice of the doctor regarding its use.

Q. Does azelastine cause drowsiness/nose bleeds/weight gain/raise blood pressure/make you tired/sleepy?
Azelastine causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects.


Content on this page was last updated on 14 June, 2014, by Dr. Varun Gupta (MD Pharmacology)