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MBA, MD Pharmacology
Last updated
29 Nov 2023 | 06:56 PM (IST)

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Aprepep 125mg Capsule

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Aprepep 125mg Capsule is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.

Aprepep 125mg Capsule is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Aprepep Capsule

  • Nausea and vomiting due to chemotherapy

Benefits of Aprepep Capsule

In Nausea and vomiting due to chemotherapy

Aprepep 125mg Capsule blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). Take it as prescribed by the doctor to get maximum benefit.

Side effects of Aprepep Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aprepep

  • Headache
  • Dizziness
  • Hiccup
  • Loss of appetite
  • Fatigue
  • Constipation
  • Diarrhea

How to use Aprepep Capsule

Take this medicine in the dose and duration as advised by your doctor. Aprepep 125mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Aprepep Capsule works

Aprepep 125mg Capsule is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aprepep 125mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Aprepep 125mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Aprepep 125mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Aprepep 125mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Aprepep 125mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Aprepep 125mg Capsule is recommended.
Liver
SAFE IF PRESCRIBED
Aprepep 125mg Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aprepep 125mg Capsule may not be needed in these patients. Please consult your doctor.

What if you forget to take Aprepep Capsule?

If you miss a dose of Aprepep 125mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Aprepep 125mg Capsule helps prevent nausea and vomiting caused by certain chemotherapy medicines.
  • It will not help if you already have nausea and vomiting.
  • Do not use it continuously for a long time.
  • It is recommended to take Aprepep 125mg Capsule 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
  • It may damage sperms and may harm the baby if used during pregnancy or breastfeeding.

Fact Box

Chemical Class
Phenylmorpholine Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
NK1 Antagonists

Interaction with drugs

Taking Aprepep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Alestol, Astelong, Astem
Life-threatening
Brand(s): Azep, Arzep, Optihist AZ
Life-threatening
Brand(s): Antep, C Lep, Ametol
Life-threatening
Brand(s): Dofcet
Life-threatening

Patient concerns

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NAUSEA AND VOMITING DUE TO COLD
Dr. Sunil Sekhri
Diabetology
Tab Domstal 1 tab Stat and keep yourself warm
Vomiting, nausea neck pain backside
Dr. Vijay Verma
ENT
Neck pain may be due to nausea NAD vomiting Visit physician for the same
arrow

User feedback


FAQs

Q. What are Aprepep 125mg Capsule capsules/ what is Aprepep 125mg Capsule used for?

Aprepep 125mg Capsule is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery

Q. How does Aprepep 125mg Capsule work?

Aprepep 125mg Capsule is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
  2. Aprepitant. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

1152
Inclusive of all taxes
MRP1188  3% OFF
3.0 capsules in 1 strip
SOLD OUT
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