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04 Jul 2019 | 12:45 PM (IST)
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Apidra 100 IU Cartridge


Introduction of Apidra Solution for Injection

Apidra 100 IU Cartridge is a type of rapid-acting insulin used in the treatment of diabetes mellitus. It helps to control blood sugar level and prevents long-term complications. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines if prescribed by your doctor. It may cause hypoglycemia (low blood sugar level) as a side effect.

Uses of Apidra Solution for Injection

Apidra Solution for Injection side effects

  • Hypoglycemia (low blood sugar level)

How to use Apidra Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Apidra Solution for Injection works

Apidra 100 IU Cartridge is a fast-acting insulin, starts working within 10-20 minutes after injection. It works similar to insulin produced by the body. Insulin facilitates reuptake of glucose in muscle and fat cell and also block the release of glucose from the liver.

Apidra Solution for Injection related warnings

It is unsafe to consume alcohol with Apidra 100 IU Cartridge. Taking Insulin Glulisine with alcohol may affect blood glucose levels in patients with diabetes.
Apidra 100 IU Cartridge may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Apidra 100 IU Cartridge is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Apidra 100 IU Cartridge should be used with caution in patients with kidney disease. Dose adjustment of Apidra 100 IU Cartridge may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Apidra 100 IU Cartridge should be used with caution in patients with liver disease. Dose adjustment of Apidra 100 IU Cartridge may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised.

What if you miss a dose of Apidra Solution for Injection?

If you have missed a dose of Apidra 100 IU Cartridge, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Apidra 100 IU Cartridge
₹115.3/ml of Solution for Injection
save 40%

Expert Advice

  • Take it 15 minutes before a meal or within 20 minutes after starting a meal.
  • Hypoglycemia (low blood sugar level) is a common side effect. Monitor your blood sugar level regularly. 
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites.
  • Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator  (2°C–8°C).
  • Do not use if the preparation is no longer clear and colorless or if it contains particles.

Interaction with Drugs

Taking Apidra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Defmark, Zacdef, Ecodef
Brand(s): Stacort
Brand(s): Psycool, Proparise
Brand(s): Densol
Brand(s): Nudiglue-C
Brand(s): Digeplex T
Brand(s): Zencort-M, Welone, Rigapred
Brand(s): Leparox, Prx
Brand(s): Kopram, Ecit, Escnx

Patient Concerns

Questions Related to Apidra

Can you interpret and let me know c peptide result if that's normal. I am type 1 diabetic and I doubt this test
Dr. Ila Jain Khandelwal
Dear PATIENT you for sharing your reports with me. C Peptide levels are generally high in type 2 diabetes or insulin resistance while levels are generally low in type 1 diabetes. The values can also vary depending upon anti diabetic or insulin medicine if you are taking. Please consult a diabetologist for the exact interpretation.
I have type 2 diabetes. Need to know economic alternative for Jalra 50mg. Already following germe forte 2mg. Also need alternative for ivepred.
Dr. Sanjay Bhatt
Diabetes Specialist
Almost all alternatives of good company are of same priceYou need to change saltDiabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).
Do you have any questions related to Apidra 100 IU Cartridge?

User Feedback


Q. I am taking pioglitazone for diabetes. Can I take Apidra with it?

You have to be extra careful if you are taking both pioglitazone and glulisine. Pioglitazone can cause fluid retention in your body, especially when used in combination with insulin. You may develop symptoms and signs of heart failure or if you already have heart failure, it may get aggravated. Take the advice of your doctor.

Q. I started using Apidra recently and was told to not inject into the same spot over and over again. Why?

If you use the same spot repeatedly, your body reacts by creating changes in the fatty tissue just under the skin. It can either cause lipodystrophy or lipohypertrophy. In lipodystrophy, the fat tissue becomes thin and creates a pit under the skin. Whereas, in lipohypertrophy, a little extra fat tissue grows at the frequently used injection spot and creates a lump just under the skin. Either one of these will change the absorption time of insulin resulting in delayed action. Also, many people do not like the way these lumps and pittings look.

Q. What if I accidentally inject Apidra into a muscle?

You should learn to correctly inject insulin just beneath the skin, by pinching up some skin and fat. Injecting Apidra into a muscle would make its absorption even more rapid. As a result, the chance of having a serious episode of hypoglycemia or low blood sugar would increase.

Q. I have been taking metoprolol for high blood pressure for a long time. Do I need to be careful about anything if I have started glulisine now?

Yes, you need to be careful because symptoms of low blood sugar (hypoglycemia) like increased heart rate may not be noticed by you. Keep a regular check on your blood sugar and consult your doctor if the problem persists.

Q. Can Apidra be stopped once started?

It depends on whether you have type I diabetes mellitus (body does not produce insulin) or type II (body does not respond to insulin). With type I, insulin is the only treatment available, and you cannot stop it. With type II diabetes mellitus, you may be able to go off insulin if you can get your blood sugar under control with proper diet and exercise. Always consult the doctor in case you want to stop Apidra.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1251.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 733.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 721.
  4. Insulin glulisine. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2004 [revised Aug. 2008]. [Accessed 12 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
A licensed pharmacy from your nearest location will deliver Apidra 100IU Cartridge. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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3 ml in 1 cartridge
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