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Ampicillin(500 mg),Cloxacillin(NA)


Ampicillin(500 mg)


Ampicillin is used to treat bacterial infections such as lung infections, ear, skin, and urinary tract infections.

How it works

Required for blood to clot (thrombocytopenia), reduced oxygen carrying capacity of blood due to destruction of red blood cells (hemolytic anemia).Ampicillin belongs to a group of antibiotics called penicillin antibiotics. Ampicillin kills a wide range of infection-causing bacteria, It acts by stopping  the bacterial cell wall formation that is essential for bacterial growth and survival, thereby killing the bacteria.

Common side effects

anaemia., itching of skin, interstitial nephritis, inflammation of large intestine, Stevens-Johnson syndrome, skin rash, abnormal blood counts, urge to vomit, Diarrhea, redness of skin, and vomiting, and toxic epidermal necrolysis, hepatitis and abnormal liver function including yellowing of the skin and eyes



Cloxacillin is used to treat bacterial infections in the body affecting the ear, nose, throat, lungs (pneumonia), skin and skin structure infections, urinary bladder infection (cystitis), infection of the valves of the heart and  bone infections. It is also used to treat leprosy and to prevent infection during surgery.

How it works

Cloxacillin belongs to penicillin group of antibiotics. It kills the bacteria which are actively multiplying in the body, by inhibiting the formation of their cell wall.

Common side effects

bleeding, Nausea, hives, abdominal cramps, mild to severe allergic reactions consisting of shortness of breath, abdominal pain, vomiting, bruising, pink or dark urine, black and hairy tongue, unusual tiredness., itching or discharge from the vagina, yellowing of eyes or skin, diarrhea, rash, seizures, white patches on the tongue, sore tongue or mouth, swelling of lips/face/ tongue, gas


2 Substitutes
Sorted By
    (1 Injection in Vial)
    Veritaz Healthcare Ltd
    Rs. 14.43/Injection
    Rs. 14.43
    pay 808% more per Injection
    (1 Injection in Vial)
    Elder Pharamaceuticals Ltd
    Rs. 9.30/Injection
    Rs. 9.30
    pay 485% more per Injection

Expert advice

  • Do not take ampicillin with food or milk.
  • Do not start or continue the ampicillin suspension/capsule and consult your doctor if you are allergic (hypersensitive) to ampicillin, penicillin, cephalosporin, any other antibiotic of this class or any other ingredient of suspension/capsule.
  • Do not start or continue the ampicillin suspension/capsule and consult your doctor if you suffer from liver problems ar diabetes.

Frequently asked questions


Q. Is ampicillin/Megapen a prodrug?
No, ampicillin is not a prodrug.

Q. Does ampicillin cross placenta? Is ampicillin safe during pregnancy?
Ampicillin can cross placenta. There is no evidence of ampicillin causing harm during pregnancy. However, ampicillin should be given only if the potential benefit justifies the potential risk to the infant.

Q. Is ampicillin and amoxicillin the same? Is ampicillin the same as penicillin? Is ampicillin a cephalosporin? 
Ampicillin and amoxicillin belongs to the same group of penicillin antibiotics, but differ slightly in their uses. Ampicillin is not a cephalosporin.

Q. Is ampicillin light-sensitive?
Yes, ampicillin is light sensitive it should be kept away from sunlight.

Q. Can I take ampicillin for strep throat, tooth infection, sore throat, chlamydial and bacterial vaginitis? Does ampicillin cover anaerobes, listeria?
Ampicillin can be used to treat strep throat, tooth infection, sore throat, bacterial vaginitis, and infections caused by anaerobes and listeria. It is not typically used to treat chlamydia.

Q. Can I take ampicillin with food, milk or alcohol?
Ampicillin should be taken either 1 hour prior or 2 hours after eating food or taking milk. Ampicillin does not have significant interaction with alcohol, however it is advisable not to drink or limit the use of alcohol while you are taking antibiotics.

Q. Can I take ampicillin with Advil (ibuprofen), Tylenol (paracetamol) and Benadryl?
Ampicillin can be taken with paracetamol and Benadryl. Ampicillin when taken with ibuprofen may increase the effects of either drug.


Q. Is cloxacillin a penicillin/antibiotic? What does it treat?
Cloxacillin belongs to a class of medication called penicillin antibiotics. It does not contain penicillin but is structurally similar to it. It is is used to treat bacterial infections in the body affecting the ear, nose, throat, lungs (pneumonia), skin and skin structure infections, urinary bladder infection (cystitis), infection of the valves of the heart, bone infections, especially those caused by the resistant staphylococcus bacteria. It is also used to treat leprosy and lepra-reaction seen in leprosy, and to prevent infection during surgery.

Q. Is cloxacillin the same as amoxicillin?
Cloxacillin is not the same as amoxicillin, but they belong to the same class of medication called penicillin antibiotics.

Q. Is cloxacillin used for treating tonsillitis/ boils/acne/chlamydia/streptococcus infections?
Cloxacillin is not commonly used to treat tonsillitis/boils/acne/chlamydia. It may be used to treat streptococcus infections but is more commonly used for staphylococcus infections.

Q. Does cloxacillin use affect the pill?
Cloxacillin is known to reduce efficacy of the birth-control pill. Hence a second effective method of contraception should also be used to prevent unwanted pregnancies.

Q. Does cloxacillin cause weight gain or sleepiness? Does it affect menstruation?
These are no studies showing any relation between weight gain, sleepiness and cloxacillin use. It is not known to affect menstruation.

Q. Should cloxacillin be taken by pregnant or breast-feeding women?
Cloxacillin is unlikely to cause harm to the fetus. However, the safety of this drug has not been established in pregnant women. It should be used only after consultation with the doctor. Cloxacillin is secreted in breast milk. So it should be taken by women who are breast-feeding only as per the doctor’s instructions.

Q. Can I take Advil (ibuprofen)/ Tylenol (paracetamol) with cloxacillin?
There are no known interactions between cloxacillin and Advil (ibuprofen)/ Tylenol (paracetamol). But doctor’s advice should be followed about taking both the medications together.

Q. Is cloxacillin safe for G6PD?
Yes, cloxacillin can be safely used in patients who have deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD).

Q. Can I take cloxacillin with milk?
Cloxacillin should be taken at least 30 minutes before or 2 hours after consuming milk or food.

Q. Does cloxacillin expire?
Cloxacillin has an expiry date, beyond which it should not be consumed. Please refer to the pack or package insert for the expiry date.

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