Medicine Overview of Amphotin Lip Injection
Amphotin Lip 50 mg Injection is used in the treatment of severe fungal infections and kala-azar
Side Effects of Amphotin Lip are Headache, Injection site pain, Vomiting, Nausea, Stomach cramp, Fever, Anemia (low number of red blood cells), Heartburn, Rapid breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Amphotin Lip 50 mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
In Depth Information on Amphotin Lip Injection
- Before you take amphotericin B, inform your doctor if you suffer from diabetes, liver/kidney problem or are on dialysis or have low potassium level in blood.
- You should monitor your condition through regular laboratory evaluation of potassium, magnesium as well as renal, hepatic and hematopoietic function.
- Take precautions as amphotericin B may reduce the ability to drive or operate machinery.
- Tell your doctor if you are or planning to become pregnant or are breastfeeding.
Amphotin Lip Injection related warnings
Interaction with alcohol is unknown. Please consult your doctor.
Amphotin Lip 50 mg Injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Amphotin Lip 50 mg Injection is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Amphotin Lip 50 mg Injection may cause side effects which could affect your ability to drive.
Amphotin Lip 50 mg Injection is safe to use in patients with kidney disease. No dose adjustment of Amphotin Lip 50 mg Injection is recommended.
However, inform your doctor if you have any underlying kidney disease.
There is limited information available on the use of Amphotin Lip 50 mg Injection in patients with liver disease. Please consult your doctor.
If you miss a dose of Amphotin Lip 50 mg Injection, please consult your doctor.
Frequently asked questions about Amphotin Lip Injection
Q. Is Amphotin Lip fungistatic or fungicidal?
Amphotin Lip is fungicidal in nature, it acts by killing the fungus
Q. Is Amphotin Lip light sensitive?
Amphotin Lip is not light sensitive
Q. What is Amphotin Lip liposomal?
Liposomal Amphotin Lip is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphotin Lip can substantially improves drug safety especially nephrotoxicity associated with the drug
Q. Is Amphotin Lip an antibiotic?
Yes, Amphotin Lip is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)
Q. Is Amphotin Lip testing dose needed?
Yes, administration of Amphotin Lip is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity
Q. How is Amphotin Lip administered?
Amphotin Lip is either administered as intravenous injection or infusion by a registered medical professional only
Q. How does Amphotin Lip cause nephrotoxicity and hyperkalemia?
Amphotin Lip can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.
Severely interacts with other drugs like
Taking Amphotin Lip with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Deflazacort: Ducort, Defmark
Medicines with composition Amikacin: Mikasun, Vizocin, Amricin
Medicines with composition Itraconazole: Itraspan, Itzo, Canzit, Cositra
Medicines with composition Tobramycin: Bactob
Medicines with composition Prednisolone: Ranisol
Medicines with composition Gentamicin: Begenta, Indogenta
Medicines with composition Fluconazole: Fungis
Medicines with composition Ketoconazole: Ketozoe, Ketazol
Medicines with composition Budesonide: Budojet
Medicines with composition Methylprednisolone: Zencort-M
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