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Amphonex 50mg Injection
Prescription Required
Overview
Introduction
Amphonex 50mg Injection is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills fungi by destroying the fungal cell membrane.
Amphonex 50mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood
It may lead to a few common side effects like headache, nausea and vomiting. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.
Amphonex 50mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood
It may lead to a few common side effects like headache, nausea and vomiting. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.
Uses of Amphonex Injection
Side effects of Amphonex Injection
Common
- Headache
- Vomiting
- Nausea
- Stomach cramp
- Fever
- Anemia (low number of red blood cells)
- Heartburn
- Rapid breathing
How to use Amphonex Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Amphonex Injection works
Amphonex 50mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
Safety Advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amphonex 50mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Amphonex 50mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
CONSULT YOUR DOCTOR
Amphonex 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amphonex 50mg Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amphonex 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Amphonex 50mg Injection is recommended.
However, inform your doctor if you have any underlying kidney disease.
However, inform your doctor if you have any underlying kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Amphonex 50mg Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Amphonex Injection?
If you miss a dose of Amphonex 50mg Injection, please consult your doctor.
Alternate Brands
For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips
- It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
- Amphonex 50mg Injection can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
- Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
- Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Interaction with Drugs
Taking Amphonex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec, Virol
SERIOUS
Brand(s): Adesera, Adheb, Adfovir
SERIOUS
Brand(s): Mikasun, Vizocin, Amricin
SERIOUS
Brand(s): Densol
SERIOUS
Patient Concerns
Do you have any questions related to Amphonex 50mg Injection ?
User Feedback
What are you using Amphonex Injection for?
Severe fungal*
100%
*Severe fungal infections
How much was the improvement?
Poor
92%
Average
8%
What were the side-effects while using Amphonex 50mg Injection?
Headache
100%
How do you take Amphonex Injection?
With food
100%
Please rate Amphonex 50mg Injection on price
Not Expensive
100%
FAQs
Q. Is Amphonex fungistatic or fungicidal?
Amphonex is fungicidal in nature, it acts by killing the fungus
Q. Is Amphonex light sensitive?
Amphonex is not light sensitive
Q. What is Amphonex liposomal?
Liposomal Amphonex is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphonex can substantially improves drug safety especially nephrotoxicity associated with the drug
Q. Is Amphonex an antibiotic?
Yes, Amphonex is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)
Q. Is Amphonex testing dose needed?
Yes, administration of Amphonex is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity
Q. How is Amphonex administered?
Amphonex is either administered as intravenous injection or infusion by a registered medical professional only
Q. How does Amphonex cause nephrotoxicity and hyperkalemia?
Amphonex can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.
Related Products
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
- Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1424.
- Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1571-75.
- Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 836-38.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 68-69.
- Medsacpe. Amphotericin. [Accessed 29 Mar. 2019] (online) Available from:
- Amphotericin B. San Dimas, California: Gilead Sciences, Inc.; 2000. [Accessed 04 Feb. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5):4-6. [Accessed 29 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
Manufacturer/Marketer Address
17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
A licensed pharmacy from your nearest location will deliver Amphonex 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹3229.66
MRP₹4037.07 Get 20% OFF
1 Injection in 1 vial
1 Vial
Not returnable Read policy
Additional offers
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