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AMPHONEX 50MG INJECTION

Injection
MRP: Rs. 7609.52 for 1 vial(s) (1 injection each)
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Composition for AMPHONEX

Amphotericin B(50 mg)

food interaction for AMPHONEX

alcohol interaction for AMPHONEX

pregnancy interaction for AMPHONEX

lactation interaction for AMPHONEX

food
alcohol
pregnancy
lactation
It can be taken with or without food, but it is better to take Amphonex 50mg injection at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Amphonex 50mg injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
PROBABLY SAFE
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION for AMPHONEX

Amphotericin B(50 mg)

Uses

Amphonex 50mg injection is used in the treatment of serious fungal infections and kala-azar.

How it works

Amphonex 50mg injection belongs to class of medications called polyene antimycotics. It acts on the outer covering (cell membrane) of the fungus resulting in leakage of essential nutrients from within the cells, thereby killing them.

Common side effects

Increased glucose level in blood, Loss of appetite, Fever, Chills, Blurred vision, Nausea, Abnormal heart rhythm, Headache, Abnormal breathing, Fainting, Dizziness, Vomiting, Decreased potassium level in blood

SUBSTITUTES for AMPHONEX

17 Substitutes
Sorted By
RelevancePrice
  • PHOSOME 50 MG INJECTION
    (1 injection in vial)
    Cipla Ltd
    Rs. 4784.75/injection
    Injection
    Rs. 4784.75
    save 37% more per injection
  • SPOROTAR 50MG INJECTION
    (1 injection in vial)
    Emcure Pharmaceuticals Ltd
    Rs. 4336.30/injection
    Injection
    Rs. 4336.30
    save 43% more per injection
  • ENVOCIN 50MG INJECTION
    (1 injection in vial)
    Sun Pharmaceutical Industries Ltd
    Rs. 7900/injection
    Injection
    Rs. 7900
    pay 4% more per injection
  • AMPHOJECT 50MG INJECTION
    (1 injection in vial)
    Panacea Biotec Ltd
    Rs. 7142.86/injection
    Injection
    Rs. 7142.86
    save 6% more per injection
  • AMPHOTRET 50MG INJECTION
    (1 injection in vial)
    Bharat Serums & Vaccines Ltd
    Rs. 268/injection
    Injection
    Rs. 268
    save 96% more per injection

Top Physicians

  • Dr. Khoobsurat Najma
    MBBS
    4.9
  • Dr. M. K. Singh
    MBBS, MD
    4.8
  • Dr. Ashutosh Shukla
    MBBS, MD, Diploma, Fellowship
    4.6
  • Dr. R. S. Rawat
    MBBS, MD
    4.5
  • Dr. R. R. Dutta
    MBBS, MD
    4.4

Expert advice for AMPHONEX

  • Before you take amphotericin B, inform your doctor if you suffer from diabetes, liver/kidney problem or are on dialysis or have low potassium level in blood.
  • You should monitor your condition through regular laboratory evaluation of potassium, magnesium as well as renal, hepatic and hematopoietic function.
  • Take precautions as amphotericin B may reduce the ability to drive or operate machinery.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions for AMPHONEX

Amphotericin B

Q.Is amphotericin B an antibiotic?
Yes, amphotericin B is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)

Q.Is amphotericin B fungistatic or fungicidal?
Amphotericin B is fungicidal in nature, it acts by killing the fungus

Q.Is amphotericin B testing dose needed?
Yes, administration of amphotericin B is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity

Q.Is amphotericin B light sensitive?
Amphotericin B is not light sensitive

Q.How is amphotericin B administered?
Amphotericin B is either administered as intravenous injection or infusion by a registered medical professional only

Q.What is amphotericin B liposomal?
Liposomal amphotericin B is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of amphotericin B can substantially improves drug safety especially nephrotoxicity associated with the drug

Q.How does amphotericin B cause nephrotoxicity and hyperkalemia?
Amphotericin B can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.

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Content on this page was last updated on 11 September, 2015, by Dr. Varun Gupta (MD Pharmacology)